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Requip and Vomiting: What Users Say

Vomiting: mentioned by 15 users (12.3%)

Based on user experiences from 122 Requip reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

nausea 18.9%
vomiting 12.3%
drowsiness 5.7%
tiredness 4.9%
insomnia 3.3%
swelling 3.3%
depression 2.5%
dizziness 2.5%
headaches 2.5%
nightmares 2.5%

Reviews for Requip

Commonly mentioned side effects
  • Sta...
  • Taken for 5 to 10 years
  • July 10, 2016

For Restless Legs Syndrome "I have had severe refractory full body RLS for 10 years. My symptoms are 24/7 without medication. I was prescribed Requip, and it was one of the worst nights of my life! I was terribly nauseous and vomited all night. But even worse than that was the fact that it made my RLS much worse. I had the same results with Mirapex. My doctor tried me on several other meds. None of them worked, and some made the RLS worse like the Requip and Mirapex did. I ended up hurting my shoulder pretty badly, and my doctor prescribed Tramadol. Lo and behold, once it got into my system, the RLS was gone! I've been taking the Tramadol every 6 hours for 9 years now and am still symptom-free and doing great!"

1 / 10
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101 Report
  • Jan...
  • Taken for 2 to 5 years
  • March 22, 2015

For Restless Legs Syndrome "I started Requip 1 mg at bedtime. It worked great for 3-4 months. My Dr. increased the dosage so I now take 3 mg at bedtime. Again, it worked great for a few months, and then the symptoms reappeared. The Requip is better than nothing, but I was up pacing the floors when I should have been sleeping. My husband suggested acupuncture, and that has made a huge difference. I take the Requip 3 mg with 3 saltines to prevent nausea and vomiting. I have an acupuncture treatment every 2 weeks, and no problems when I go to bed."

6 / 10
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76 Report
  • bla...
  • February 21, 2015

For Restless Legs Syndrome "Let me first start by saying that Requip did work very well to control my restless legs syndrome. (I have terrible, uncontrollable leg movement/pain.) However, the side effects of the higher dosage made me very sick. Approximately one hour before bedtime, I had taken the pill. I began to feel extremely nauseous, with excruciating stomach cramps, chills, and my head started spinning. I could barely make it to the bathroom, where I immediately threw up. I found relief soon thereafter from the side effects. I continued having a mild stomach ache about 4 hours later. Requip should definitely be taken in a smaller dosage at first. Then move up gradually when you feel that the dosage isn't covering all your pains. I take Requip daily and have for 10 years for my RLS. Feel better!"

10 / 10
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Frequently asked questions

  • Sne...
  • December 25, 2015

For Restless Legs Syndrome "Have been taking Requip for 6 months. You have to be careful not to exceed the recommended dosage and keep it as low as possible. It will or won't work for you, don't get impatient and take more shortly after the first dose. I am lucky in that I do not get the vomiting/stomach issues. But you can almost time it to the minute. I start to cough, my nose feels like it is swollen inside and no air can get through. Draining into the throat makes the cough much worse. 2 1/2 to 3 hours later, all better. Higher doses (2 mg) make it much worse. However, it still beats RLS without a doubt!!"

10 / 10
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  • Anonymous
  • Taken for 5 to 10 years
  • July 8, 2012

For Restless Legs Syndrome "I began taking Requip when it first came on the market for restless legs syndrome. My symptoms got better for about 6 months, then slowly got worse. As the dosage increased, so did the symptoms. What began as nightly leg twitching/aches got so bad I began having anxiety attacks at night. It was very common for me to have an anxiety attack and end up getting up on the computer until about 3 a.m. until I couldn't keep my head up anymore (getting up at 5 a.m. for work, I was a walking zombie). Also, as the dosage increased, I began having symptoms while sitting at my desk at work and also experienced nightly vomiting/dry heaving. I became suicidal. After 6 years, I switched to Mirapex. After 5 years, I'm on minimal dosage with incredible results. I feel human again!"

2 / 10
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58 Report

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  • Ste...
  • Taken for 2 to 5 years
  • December 3, 2014

For Restless Legs Syndrome "I've had an extreme case; it starts in my legs and finds its way to the arms and everywhere else. I've spent more nights than I care to remember screaming into my pillow. Requip completely quiets the syndrome - 100%. But... then I spend the next two hours wishing I hadn't taken it due to the endless projectile vomiting. I cannot take it, as I had developed hypophosphatemia from the vomiting. (I now take Klonopin 1 mg at bedtime, and it prevents RLS extremely well.)"

5 / 10
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43 Report
  • Sho...
  • January 21, 2015

For Restless Legs Syndrome "My restless legs syndrome has become really annoying in the past few months. I was on Gabapentin, which seemed to help, but it started to become less effective, so the Dr. switched to Requip. On my first night, I felt sick and had flu-like symptoms. The next day, I took it early and immediately felt sick and started to throw up and felt chills and then felt hot. This medicine did absolutely nothing for me besides make me sick."

1 / 10
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44 Report
  • Drm...
  • Taken for 1 to 2 years
  • February 15, 2015

For Restless Legs Syndrome "It works great for Restless Legs Syndrome. I can finally sleep at night. I'm 41, and the first time I experienced RLS, I was 8. I could just do without the side effects. I'm on 2 mg, and I think if it was upped, my side effects would worsen. I feel sick to my stomach. I vomit at times. I've had hallucinations. It makes me feel like my blood sugar is dropping, but it's not. Just makes my body not feel right. Thinking about finding something else without these side effects."

8 / 10
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34 Report
  • kas...
  • March 17, 2009

For Restless Legs Syndrome "After taking Mirapex for about a year, then developing horrible nausea and vomiting, my doctor switched me to Requip 0.5 mg at bedtime. This time, the relief from RLS only lasted about a week. After that, the nausea and vomiting returned with a vengeance, and I had to discontinue the medication immediately."

2 / 10
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  • Anonymous
  • May 22, 2011

For Restless Legs Syndrome "Has anyone noticed that Requip XL has more side effects than regular Requip? My doctor has been giving me samples of Requip XL to take instead of my regular Requip (insurance will not pay for Requip XL). I take 6 mg per day and have taken it for many years. My dosage has been as much as 12 mg, but I have reduced the dosage to get down to 6 mg. I still have breakthrough restless legs even when I take my medicine on schedule, and sometimes when I do not take my medicine on time, I will have restless legs for hours after I take my dose. I am having severe nausea, vomiting, sweats, flushing, hot flashes, dizziness, tiredness, etc."

9 / 10
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25 Report
  • Nic...
  • December 5, 2015

For Restless Legs Syndrome "I was taking amitriptyline for years, but started losing memory, then I started losing time. With Alzheimer's strong in family history, I had to make a change to my medication. I tried Horizant, 300 mg for a while, then bumped up the mg to 600/night. It still wasn't helping. My legs got worse and worse. I was taking Benadryl just to sleep, and sometimes even that didn't work. Fed up with crying and writhing in pain, I called my doctor who put me back on Requip. 3 mg to start. It was terrible! Incredible nausea, vomiting, sweats, syncope.... worst night of my life! I thought I was going to die! Luckily, my fiancé is a medical assistant, otherwise, I probably wouldn't be able to write this."

1 / 10
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27 Report
  • Tho...
  • January 1, 2011

For Restless Legs Syndrome "It took over 5 years before I was able to find out what I had in my legs, and behold, it was Restless Legs Syndrome. They gave me Requip, and it was great for about a month or so, no pain when I sat down, which was when I always felt the pain. But like some other users, I would wake up and dry vomit, or vomit, depends on how long it was since my last meal. It was not worth the morning sessions, so I stopped taking it. I hope this works for other people, but I am waiting for a better option. I would like to point out also my legs didn't hurt after I threw up, but it just was not worth it."

5 / 10
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24 Report
  • Rls...
  • July 2, 2015

For Restless Legs Syndrome "The very first night I started Requip, I vomited violently all night."

1 / 10
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23 Report
  • Anonymous
  • April 3, 2009

For Periodic Limb Movement Disorder "This medication caused me severe nausea and vomiting."

1 / 10
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26 Report
  • Jai...
  • Taken for 1 to 6 months
  • July 26, 2015

For Periodic Limb Movement Disorder "I was given this med for RLS/PLM. This medication kept me up most of the night with a bucket to vomit into. Hummm.... Which to choose, RLS/PLM vs. severe nausea/vomiting?"

1 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.