Prometrium for Perimenopausal Symptoms User Reviews

• Mis...
• Taken for 1 to 6 months
• July 12, 2018

"I’m 46, perimenopausal, regular periods. I had very bad PMS and sore breasts for 2 weeks before period, and a serious inability to lose weight. I started this 3 months ago and I’m down 8 pounds, sleeping better and PMS is way better although it took the full 3 months for it to start helping. Now weighing 140 pounds at 5’7. I was very worried about weight gain on this, but it was opposite for me! I take 100mg at bedtime and stop it for 7 days during my period. I also started on Estro support (DIM) to lower estrogen as well. That also made a huge difference! Get your hormones tested so you know exactly what’s going on in your body!"

• Dan...
• Taken for less than 1 month
• May 2, 2020

"After 8 days on this medication, I was having full-blown panic attacks. I was on 200 mg daily. This is a horrible side effect, just want people to know about. It may not do that to everyone, but if you have ever had anxiety in the past, be careful on your dosage."

• kbe...
• November 12, 2010

"Taking it at 100 mg. Didn't like the dizzy feeling. Started taking it at night, much better, but I feel it building up in my system over time. I wish I could take half or 3/4 as much, but it is not available in those doses. I have absorption issues, and the liquid form is great except I can't cut it in half. I do like what it does for my thinking, digestion, emotions, etc., but over time, irritability, heavy dreaming, pregnant-like feeling build up. I am a small woman, about 110 lbs, 5 feet, and wish smaller doses were available. A little bit goes a long way."

• Bea...
• December 23, 2016

"I'm 42 years old and perimenopause has taken over my life. My estrogen dominance was so bad that for 8 whole days before I even started my period, I was almost bedridden. My breasts were so sore, it was as if they were engorged, and I, at times, felt a low-grade fever coming on. I have a 21-day cycle. I have one week a month that I felt pretty OK... Only one week a month!! Went to the OBGYN and begged for help. I'm now on day 5 of Prometrium. So far, my head is clear, no boob pain, I'm awake not tired, not hungry either. I do have some uterine cramps every afternoon for some reason. I can't wait to see how my whole cycle will be. So far so good, very happy."

• SL2...
• Taken for less than 1 month
• June 12, 2022

"I tried taking 100 mg of Prometrium daily for 3 days after entering menopause at age 51. I have not had a period in almost 1 year. It is awful stuff. It immediately gave me a horrible dull headache, a sense of depression, and a feeling of malaise. I'll stick with natural remedies for hot flashes, which Prometrium also made worse, frankly. It is also worth noting that I have never taken birth control or any other hormone supplements."

• Ste...
• Taken for 1 to 6 months
• August 2, 2020

"I started taking 200 mg day 14-28 of my cycle. My doctor had me combine it with a progesterone cream. My breasts became bigger and much more tender. I began steadily gaining weight, up 7 lbs now. I am going to go off the Prometrium and go back to the cream only and see if the sore breasts and weight gain subside. The cream worked well for me in the past, not sure why my doctor felt I needed both the cream and the pill. I do feel progesterone is wonderful for reducing mood swings and food cravings. That issue is all but abolished when I'm on the progesterones, I just am obviously not a fan of the weight gain. So if the goal of the medicine is to increase progesterone levels and decrease mood swings, it is effective."

• San...
• Taken for 1 to 2 years
• April 21, 2025

"The effect of Prometrium for perimenopausal symptoms alongside application of Estrogel is as intended. I am a shift worker who had to get clarification from a second doctor as to when to take on a 24/7 rotating roster. My biggest problem is swallowing the capsule, I have never had problems swallowing anything, but the capsule more often than not is hard to swallow and seems to make its way back up my esophagus, causing discomfort. I now have to take it well before bedtime and drink up to 2 liters of water to avoid the feeling of this well into the night. After Googling this problem, I have found many posts describing the same problem."

• Fem...
• Taken for less than 1 month
• October 2, 2020

"I developed severe tinnitus, and after 1 week, couldn't take generic progesterone for Prometrium anymore."

• Anonymous
• May 18, 2011

"I take this medicine in conjunction with applications of Divigel."