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Ondansetron for Nausea/Vomiting, Postoperative User Reviews

Rating: 7.3

Ondansetron has an average rating of 7.3 out of 10 from a total of 16 reviews for the treatment of nausea/vomiting, postoperative. 75% of reviewers reported a positive experience, while 25% reported a negative experience.

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Reviews for Ondansetron

Commonly mentioned side effects
  • gwa...
  • Taken for less than 1 month
  • February 6, 2020

Ondansetron "So I was prescribed Zofran when I got my wisdom teeth out! Worked like a charm! I also have had this huge fear of vomiting, so bad that I’ll work myself up and become so anxious that I feel like I’ll vomit. This little tablet helps a bunch!"

10 / 10
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22 Report
  • rit...
  • Taken for less than 1 month
  • April 30, 2014

Ondansetron "Was given Zofran for nausea in the recovery room before going to the same-day surgery unit prior to release. Ended up with nausea, dizziness, vomiting, and shivering. After the second vomiting episode, I was given Phenergan and was able to be released in another couple of hours."

1 / 10
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14 Report
  • Ood...
  • Taken for 2 to 5 years
  • November 30, 2015

Ondansetron "I've been given Zofran pre-op and post-op for all ten surgeries, including my hysterectomy, since I always have nausea and vomiting before/after surgery. I've even gotten Zofran during ER visits for migraines, gallstones, and ovarian cyst ruptures. This is my go-to antiemetic, and I even have the ODT in my nightstand in case I ever get too nauseous. Amazing drug!"

10 / 10
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12 Report

Frequently asked questions

  • Anonymous
  • November 4, 2009

Ondansetron "Best anti-nausea medication available. Very effective for those undergoing chemotherapy. Also good for conditions when you are nauseous and require a narcotic analgesic - nausea will still subside. If you are allergic to other nausea medications such as Compazine and/or Reglan, like I am (severe panic attacks), Zofran is your safest bet (only side effect I have occasionally noticed is a slight headache). The only real downfall is the price of the orally disintegrating tablet because there is no generic. The non-ODT tablet does have a generic and is also very effective, but if you need relief FAST, ODT is the best way to go."

10 / 10
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15 Report
  • Mcr...
  • Taken for 1 to 6 months
  • June 14, 2019

Ondansetron "I had a gastric plication done (like gastric bypass) and woke up after surgery profusely throwing up to the point they had to sedate me again to put the anti-nausea stickers behind my ears to keep me from vomiting as soon as I woke up again. Well, they gave me the Zofran to take at home, so I would take them every 4 hours before the last dose ran out and didn't feel nauseous ever again. Really great stuff."

9 / 10
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6 Report

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  • Rup...
  • June 16, 2014

"I began taking this medication after I had a very complicated, invasive surgery due to a ruptured appendix left to leak for three days, peritonitis, etc. For the nausea that accompanied surgery and the condition itself; it worked wonders, kept me from vomiting, and kept the nausea entirely at bay. I recovered well and stopped the medication a week after surgery; however, about 3 weeks post-op, I began experiencing constant nausea and pain, without a known cause, which made my life absolutely miserable constantly. I couldn't eat or drink without nausea and feeling like I was about to vomit, couldn't function normally, lost several pounds, and felt like crap constantly. Then, my surgeon prescribed this medicine, and life was okay. :)"

9 / 10
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10 Report
  • 3be...
  • November 16, 2020

Ondansetron "I had a horrible reaction to the anesthesia after surgery and was given Zofran for the nausea. I am now three weeks taking it, and it has been a lifesaver for me. It works really fast, and the only side effect I have is hard stools."

9 / 10
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4 Report
  • Sza...
  • November 28, 2011

"I had surgery, and the postoperative narcotics made me very nauseous, and I had to throw up. A full dose (8 mg) of ondansetron helped but did not fully resolve the problem. Then I got Phenergan, and all the nausea was finally gone. I think, for me, Phenergan is a better anti-nausea medication, but while ondansetron (Zofran) barely made me sleepy, Phenergan made me very sleepy. I actually think, if you are at home or in a hospital, it is much better to take Phenergan as it seems to help more and also gives you a good sleep. If you need to go to work or school, you should take Zofran."

8 / 10
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6 Report
  • Gma...
  • Taken for less than 1 month
  • May 18, 2018

"I had dental surgery, was given one dose of ondansetron. Had an extremely bad reaction. Experienced nausea, vomiting, dry heaving, muscle twitches, seizures, couldn't open my eyes but could still hear. Three days could not eat and took sips of cola as advised by my local EMT (yes, they called 911 on me as I did feel like I was dying). Had trouble with my eyes adjusting while trying to focus, my vision would snap in and out. Now, with all that said, I have taken ondansetron several times before with no problem. You just never know."

1 / 10
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2 Report
  • Col...
  • Taken for less than 1 month
  • June 20, 2012

"Was taking the pain medicine Tylox after ACL repair and broken femur. Although the Tylox helped tremendously with the pain, I would get a nauseous feeling and vomit even when I ate before taking Tylox. The doctor gave me a prescription for ondansetron, and it worked beautifully. I take it 10-15 minutes before I eat and take the Tylox 10-15 minutes after I eat... no more nausea! Yay."

9 / 10
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2 Report
  • Man...
  • Taken for 1 to 6 months
  • August 26, 2018

"This medicine is a wonder drug. I have ulcerative colitis and an ulcer. I recently had a gastric bypass, and that's when all the problems started. I couldn't eat. I'd throw up everything. Even limiting things to one small bite every 5 minutes was too much. The doctor prescribed me Zofran and said to take it as soon as I felt the 'pressure' letting me know I was liable to throw up. With this surgery, you have to get your protein and calories in every day, or you will not lose weight. I plateaued for a while, but after getting on the Zofran and taking it 'as needed,' I've lost 78 lbs in 6 months, and eating is getting easier. I don't know how I would have survived this without the Zofran enabling me to keep my protein levels up."

10 / 10
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1 Report
  • Med...
  • Taken for 1 to 6 months
  • August 4, 2021

"Think some reviews are suspicious since the CDC wanted Phenergan, which was 10 times the medication Zofran is. The headaches are severe, and nausea/vomiting hits without warning. I tried but could not tolerate the pain and misery. Phenergan was by far superior and boosted mood because it was such a good medication and better than Zofran or any so-called antidepressant. I can't believe Zofran has replaced other medications in hospice comfort packs."

1 / 10
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1 Report
  • Bre...
  • Taken for less than 1 month
  • April 23, 2022

Ondansetron "I was prescribed this drug a few weeks back when I had an upper respiratory infection. The coughing fits got so bad they would make me throw up, and I had post-nasal drip, and the mucus made me feel sick to my stomach constantly. My Dr. gave me this to try because I couldn't really eat anything, and it works like a charm. 30 minutes after taking the ODT, I'm able to eat with no issues. I still have some left over from my URI, and I keep it on hand just in case. It's wonderful to have. I didn't have any side effects besides a slight headache, but it was completely worth it to finally be able to stomach some food and not have to get up 4 or 5 times a night feeling like I had to throw up."

9 / 10
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0 Report
  • Anonymous
  • November 8, 2009

Ondansetron "Very bad side effects: increased nausea and vomiting, trouble breathing, blurred vision, eyes would not focus, excessive dizziness."

1 / 10
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21 Report
  • pin...
  • Taken for less than 1 month
  • January 8, 2014

Ondansetron "Zofran worked wonders after my operation. Significantly decreased my nausea. It's a great medication in my eyes."

10 / 10
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7 Report
  • Ale...
  • Taken for less than 1 month
  • October 14, 2022

Ondansetron "Very efficient for postoperative vomiting. A life saver."

10 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.