Skip to main content

Omeprazole for GERD User Reviews (Page 2)

Brand names: Prilosec, Prilosec OTC, Omesec

Omeprazole has an average rating of 4.7 out of 10 from a total of 254 reviews for the treatment of GERD. 32% of reviewers reported a positive experience, while 51% reported a negative experience.

Reviews for Omeprazole

  • liqui...
  • Taken for 1 to 6 months
  • December 11, 2019

"I never had acid reflux in my life. Was given omeprazole while in the hospital for 3 days. Heart related issue. Dr wrote me prescription out for it. I have no clue why. When I tried to stop taking it. I had acid reflux really bad. So I continued to take it. Lost 30 pounds in a month. Started to have muscle spasms, head aches, complete unwellness and lost a lot of muscle mass. I was finally able to get off omeprazole. Started to gain weight back and I look healthy. This is a very bad drug from a nutritional stand point. Will never take it again."

1 / 10
Was this helpful?YesNo
80 Report
  • H-A
  • March 29, 2023

"It ruined my life. I don't even have the strength to narrate what it did to me. but it surely ruined my life. The panic attacks and anxiety. I had to be given anti-depressants only to find that this medication caused all this. I feel like crying when I think of it."

1 / 10
Was this helpful?YesNo
28 Report
  • Chux
  • Taken for less than 1 month
  • February 17, 2021

"Took omeprazole for one week, felt dizzy and decided to stop. Two weeks later I had to retake it again and that was a huge mistake I made. This medication left me feeling very very dizzy, couldn't walk on my own, gave me eye pain and weakness of the body. It took me two weeks with so many blood tonics and fluid to get back on my feet. This medication is awaful. Please no one should use it"

1 / 10
Was this helpful?YesNo
61 Report

Frequently asked questions

  • Jim
  • Taken for less than 1 month
  • September 20, 2021

"I really never comment on websites such as these, as I’ve been fairly healthy for all of my life. I was recently diagnosed with GERD and was told to take a 40 mg pill of omeprazole daily. I implore you all to exhaust all options before taking this pill. I am only on Day 1, and I have had anxiety and sentiments of hopelessness. Even as someone who is generally very happy and calm, I now cannot watch a TV series without getting anxiety after taking this medication. I will be halting its consumption and hoping that the side effects disappear soon."

1 / 10
Was this helpful?YesNo
52 Report
  • Mooge
  • Taken for less than 1 month
  • November 16, 2019

"I started taking this medicine four days ago. It makes my whole system feel suppressed. Shortness of breath, I feel dizzy, tired and like I am going to pass out. I have pressure on both sides of my head and a headache plus palpitations, it’s a really horrible drug. I can not wait for it to leave my system. I feel so ill."

1 / 10
Was this helpful?YesNo
75 Report

Are you taking this medicine?

  • Aano
  • April 30, 2020

"I had GERD in Sept and my doctor prescribed this drug. I got anxiety for 2 months non stop after I stopped the drug. I didn’t know what caused my anxiety. I took it again in March and my anxiety came back never going back to this drug again!"

Was this helpful?YesNo
68 Report
  • janes
  • Taken for 2 to 5 years
  • August 26, 2013

Prilosec (omeprazole) "A great medicine. I'm on 40 mg daily due to the feeling of my food being stuck in my throat. It was so bad at one time that I purposely made myself vomit for relief. After having my esophagus looked at - and finding out I also have a small hiatal hernia, doctor said my "flapper" doesn't close, or stay closed. So here I am religiously taking this medicine and mostly loving life. If you miss a day you will again feel miserable. I will say that over the years I have experienced "breakthrough" reflux at one time or another but never for a second day. Very happy."

10 / 10
Was this helpful?YesNo
140 Report

More FAQ

  • Robert...
  • Taken for 5 to 10 years
  • December 6, 2019

"I have been sick since about 2011 and it rapidly got worse until as of late I wasn't even barely able to leave my bed. After throwing up blood I wound up in the emergency room 2 days ago. A nurse came up to me and said hey between you and me are you sure it isn't your stomach meds (Prilosec) causing this? So I got home later that night and looked up the side effects and sure enough, severe bloating, dizziness, loss of consiousness, hallucinations were on the side effects list. So I figured I'd skip my meds for 2 days. My gut is now half the size it was, most of the pain is gone and I think I am going to scream at the doctor at my next appointment for letting this happen to me for so long. I am starting to think that doctors are not here to help."

1 / 10
Was this helpful?YesNo
72 Report
  • Mike
  • Taken for less than 1 month
  • September 21, 2019

"I am so glad I did some research and found these reviews. I literally never comment or leave reviews on anything, but decided to leave one on here. I literally just switched to Omperazole because my new insurance company doesn’t cover Lansoprozale. Have been on it for 5 days and have been experiencing terrible anxiety everyday on it and has resulted in me getting very little sleep. I even experienced something I have never experienced in my life, which was a panic attack that woke me up. Since it has been such a short time on this drug I didn’t even think of the drug being the reason for these symptoms so I thank you all for posting. I am going to stop tomorrow and see if my anxiety goes away."

Was this helpful?YesNo
71 Report
  • S alan
  • Taken for 2 to 5 years
  • January 19, 2021

"Been on this medication for a good 2 years or more. If you get any joint or tendon pain then quit this med immediately. One day both my thumbs had a lot of pain. Then about 3 months later a cascade of pain in my right shoulder, right elbow, lower back and left hip. I could barely get out of bed and impossible to even put on my socks. Seen 3 specialists but because of myopic vision they could only think arthritis . Finally I put 2 and 2 together and just quit the Omeprazole within two days started feeling better. But the damage was done as 3 tendons in my shoulder were severely damaged and my hip still has pain. Everything else went away. No faith in doctors but thanks to the internet and sites like this we will get by. It is an effective med but the side effects are very damaging."

10 / 10
Was this helpful?YesNo
54 Report
  • Daisy...
  • Taken for less than 1 month
  • January 19, 2020

"I had taken Omeprazole years ago for acid reflux and had no side effects. I recently started taking it again (20mg) and I’m on day 4. Something changed. My anxiety is very bad. Like bad! I’m out of it, feeling like I’m not in the real world. I’m dizzy and my body aches. Horrible headaches too! And I’m extremely depressed. I’m going to stop taking it tomorrow and hopefully I start to feel better this week. Hopefully don’t have withdraws or anything. Couldn’t be more worse than this anyways. I’m going to give it a 3 just because it worked years ago for me with no side effects."

3 / 10
Was this helpful?YesNo
66 Report
  • Nat
  • Taken for less than 1 month
  • September 5, 2019

"I am 26 and have dealt with heart burn and acid reflux for many years. Unfortunately, my mom deals with it too. I have been on this medication for two weeks. My heartburn is gone but I now have some horrible side effects. Dizziness, nausea, muscle pain, vertigo, blurred vision, anxiety/paranoia and more. I had a full blown panic attack, where I felt drunk. I still feel terribly anxious a day later. I don’t recommend this at all. I have decided to stop taking it and will be discussing more natural options with my doctor. I much would rather have had heartburn then experience these awful side effects."

1 / 10
Was this helpful?YesNo
69 Report
  • Jaisa
  • Taken for 5 to 10 years
  • February 11, 2020

"I've been on Omeprazole going on 10 years . No one ever mentioned anemia or any of the other problems that can come from this medication. I've been trying to get off this med for close to a year. Went down from 40mg to 20 mg not too bad. Now trying to get off 20MG. For the last week I've had chills, headaches, diarrhea, extreme heartburn anxiety, body aches exhaustion and depression. This is awful it helped reflux but at quite a price. B12. MAGNESIUM, FERRETIN SHOULD ALL BE MONITORED WHILE ON THIS MED. I had a hysterectomy and gallbladder removed in the last 5 years and wonder if those surgeries could have been avoided."

2 / 10
Was this helpful?YesNo
64 Report
  • Stacy
  • January 31, 2015

Prilosec (omeprazole) "Doc prescribed this for me but I didn't think it would help, since my main symptoms of shortness of breath and chest tightness and rarely heartburn. Left it in the cabinet for months until recurring stomach pains landed me in the ER. All blood tests, urine tests, and ultrasounds came back normal and once again my doc suggested the Prilosec. Finally caved. I kid you not, within the first day my stomach pains disappeared. I had the best nights sleep the first few days that I could remember, realizing it was actually heartburn waking me up (I contributed my early wakings to anxiety or poor sleep habits). Absolutely no side effects. I can eat whatever I want. I feel like a new person after one week. Hoping this lasts once my 14 days are up!"

10 / 10
Was this helpful?YesNo
113 Report
  • Myra
  • Taken for less than 1 month
  • February 9, 2020

"I had a bad bout of reflux and the doctor prescribed 40 mg daily. I felt relief but about 2 weeks later I had blood in my urine. I went to the doctor right away because I was freaked out. I told them that I red blood in urine was a side effect but I had to do an ultrasound to check my kidneys and bladder as well as doing urinalysis. Thankfully all tests came back ok and the doctor told me to stop the omeprazole. No more blood! I also has increased anxiety and thought it was just nervousness because I was sick. Now after reading these posts I think it was the drug."

6 / 10
Was this helpful?YesNo
59 Report
  • Iano
  • October 31, 2019

"Omeprazole is the worst pill. I took it for 3 weeks, I stopped taking it 2 weeks ago and the side effects still remain (arm and leg pain,dizziness, insomnia, depression,vision problems..) Do not take it!!!!!!"

1 / 10
Was this helpful?YesNo
61 Report
  • TTT
  • Taken for less than 1 month
  • September 25, 2021

"Worst experience, only been 8 days and I feel breathless all day! I’ve had so many panic attacks which I think because of the breathlessness it has made me constantly anxious about it then causing panic attack, I have the worst headache, and my eyes just feel strange, only on 20 mg in morning! And I’m stopping it straight away! I’m sure it works well for some but it’s a no from me! My doctor told me to up it to 40mg as it’s just my GERD but I know it’s not!!"

1 / 10
Was this helpful?YesNo
40 Report
  • wooly...
  • Taken for less than 1 month
  • February 21, 2020

"I had chest pains thought I'd pulled a muscle so took ibuprofen which gave me terrible indigestion, I went to the doctors he gave me omeprazole, it worked wonders for about 3 days then I started feeling sick, my body felt like it was shocking, I was cold couldn't sleep and I had terrible brain fog, I stopped taking it for 2 days but heartburn was awful so I started taking it again. I was prescribed 20mg twice a day so I thought I would just take one tablet in the morning, I was ok the first day but by the second all the horrible symptoms were back. I've been bake to the GP and he has given me Cimetidine instead this was great for the first day but by day 2 felt so I'll again. These meds are awful."

2 / 10
Was this helpful?YesNo
57 Report
  • Corey
  • Taken for 1 to 6 months
  • April 18, 2023

"Well, where do I start? I was experiencing a squeezing pain in the center of my chest and heart palpitations, and I was going to the hospital nearly every day. It was so bad that the pain felt suicidal like my heart was being squeezed. The doctors said it was probably acid reflux, which I thought was absolute nonsense because there was no real proof I had acid reflux. I'm 100% positive that acid reflux wouldn't cause this feeling I had in my chest. It felt more like it was heart-related. Anyhow, they prescribed me omeprazole, and I started taking it every day. After about a week, I felt like I was going to drop dead. Like no joke, I would wake up, and the feeling in my chest was unbearable like my heart was going to stop. I would wake up with a mouth full of spit, almost stopping me from breathing. I would have crazy chest pains, my heart would suddenly start beating very strangely, and I felt like any day could be my last day alive. The omeprazole also depleted my iron and vitamin D, making me anemic. It's poison."

1 / 10
Was this helpful?YesNo
20 Report
  • john...
  • Taken for 1 to 6 months
  • August 8, 2014

Prilosec (omeprazole) "This medicine saved my life. I was in pain and miserable. Tried all the OTC stuff Zantac, Pepcid, Previced, and many others with no success. Then I tried omeprazole and within day's I was better. Great medicine. Would definitely recommend."

10 / 10
Was this helpful?YesNo
104 Report
  • danbos
  • Taken for 6 months to 1 year
  • March 8, 2023

"I've been taking this wretched drug for nearly a year now and only just realized it's causing all these insane side effects that have sent me to the ER multiple times. Since taking this drug I've had horrific pains in my shoulder and left side chest (6 occasions attended AE due to thinking it was a heart attack or something), tinnitus and general ear infection/problems in both ears randomly, nausea and dizziness on occasion, liver pain/disease which is getting worse despite doing everything to make it better, itchiness on my scalp and back, pain in my ribs and sides, stiff neck, increased nervousness and anxiety, memory isn't as sharp anymore, constant feeling of impending doom and a multitude of other horrible side effects. Having been reading all these comments on various forums recently due to a particularly bad few weeks of pain and misery, it's clear that Omeprazole has had a big part to play in ruining my life this last year."

1 / 10
Was this helpful?YesNo
21 Report
  • Laney
  • Taken for 10 years or more
  • December 6, 2019

"I was on pain medicine for a kidney stone which caused severe stomach problems So MD put me on Omeprazole for 10 years. Had severe pain in my ribs. Went to the doctor continuously and he never suspected the medicine. 6 months after I stopped the medicine the pain in my ribs disappeared. Had severe pain in my shoulders and hips for 10 years. Was endlessly tired. The doctor never suspected the medicine. I went to him for years because of the fatigue. Another doctor finally diagnosed the side effect of B12 deficiency caused by omeprazole. Now have osteoporosis and have had three broken bones in the past three years. Omeprazole caused me to have strong sugar cravings because I wasn’t getting enough nutrients to my body. I now have numbness and tingling in my hands and feet and may have lupus"

1 / 10
Was this helpful?YesNo
57 Report
  • Ben
  • October 22, 2021

"I was diagnosed with acid reflux. I took 20 mg a day for 8 months. It worked fine, though I had a constant dull ache in my stomach. I decided to go off of it and I had the worst acid reflux I have ever had. I could not eat for weeks and lost 25 pounds. I completely changed my diet to low acid, got rid of all sugar and caffeine. A month later I slowly started getting better. It is now about a month since I stopped. My stomach is better, though still aches. I do not have much acid. I do have lots of wind passing. My doctor did endoscopy. Normal. He wants an MRI for pancreatic cancer. He did not believe me when I said that I thought the weight loss was from hyperacidity as a result of going off omeprazole (I read about this everywhere as a common side effect of cold turkey stopping) and recommended that I go back on Omeprazole! I am so glad I am off this stuff and returning to semblance of normality. Shocked that doctors are not concerned about this drug."

1 / 10
Was this helpful?YesNo
36 Report
  • Jacqual
  • Taken for 1 to 6 months
  • September 19, 2021

"Was put on 20mg of this for about 2 1/2 months after experiencing intense daily heartburn and acid reflux. I had taken it before for only a week and it helped so Dr prescribed it again. I have never felt what has been happening to me before. I stopped in May and it is now the end of September. Anxiety, shortness of breath, joint pain, brain fog and inability to focus my thoughts. Feeling unable to control my thoughts. Nausea, discomfort, fear, and hopelessness. When I first stopped, symptoms would be gone for a few days then back. Around August, I would go weeks without symptoms but about a week before my period, they would start coming back. Began seeing a functional medicine dr who provided me with vitamin D, trace mineral supplement and iron which I started taking in August. So afraid this is going to happen for the rest of my life and I am a single mother. Any other woman experience a uptick in their symptoms around their period? This is terrifying way to feel."

1 / 10
Was this helpful?YesNo
36 Report
  • DJano
  • Taken for less than 1 month
  • August 10, 2021

"I’ve never had anxiety or depression in my life. I started omeprazole after my dr. diagnosed me with GERD and it is the biggest mistake I never knew I could make. This drug should be illegal and I cannot stress enough to not use this. I’m currently off of it and trying to get my body back to a state of normality with it being a struggle that I shouldn’t have to face."

1 / 10
Was this helpful?YesNo
37 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.