Ocrevus for Multiple Sclerosis User Reviews (Page 3)

• John
• Taken for 1 to 6 months
• October 15, 2022

"Garbage ! 1 month after the first infusion I got about 100 moles and warts all over my body and more are appearing every day now. A few weeks later I got more MS attacks which left my toes and mouth numb."

• Sally
• Taken for 2 to 5 years
• November 13, 2020

"I have had MS for 18 years. Ocrevus is my third drug. Been on it for 3 years. Thought I was doing well until my neurologist stopped it. I’m the second person in his practice that has suffered a perforated bowel needing a colostomy. Hopefully, my surgery after 3 months can reverse the situation and I will no longer need the bag. It’s awful. There is no other reason for that to have happened to me. This drug causes serious infections. After knowing this, has this drug caused some of my other unusual health problems? Thought it was working for me, now I’m not so sure the side effects are worth it. Others in his practice have experienced odd situations. He is no longer treating his patients with this drug. BEWARE!!!"

• Rosita
• Taken for 1 to 6 months
• May 9, 2023

"This is the first time on Ocrevus and I am experiencing lots of side effects, such as neuropathy in hands & feet, neuropathic pain in back of head, & flushing. These side effects all happening in the time between the first two half doses, and there after. I am not sure if this is the right medicine for me"

• DRB
• Taken for 1 to 2 years
• August 24, 2019

"After using Rituximab, which really worked well for my multiple sclerosis (MS), my specialist put me on this medication Ocrevus, explaining it was really almost the same thing. Unfortunately, even though I have not had new lesions on this drug, I feel worse. After the first infusion, I was ill for three weeks. The second, one and a half. Third, ditto. My muscle aches and cramps are back, I have next to no energy, and terrible headaches. My next infusion should be in February next year, but I'm going to see if I could go back to Mabthera (Rituximab)."

• Ronnie
• May 23, 2019

"Been a year, falling more, have anxiety, nerve pain in legs, burning in calves and feet. Numb area in rectum. Gone from cane to walker. Upsetting, doctor wants another year. May be much worse. Only doing one more, and if no change, done. Feel upset and sad. Gilenya pill was better..."

• Lulu
• Taken for 6 months to 1 year
• February 26, 2019

"First treatment, my fatigue was horrible, didn't feel like getting out of bed. Told the doctor I wasn't sure I could deal with another infusion, he convinced me the second one would be better. Wrong! After the second one, both of my legs are very weak, not just one, and I can no longer drive and take care of my children. It has taken the most special time with my kids away."

• Ann
• Taken for 2 to 5 years
• November 20, 2019

"My sister has been on this a few years, and it hasn’t helped. She is worse than when she started and will soon need a wheelchair. I think I will discuss with her doctor at the next appointment. She has been on Copaxone and then Gilenya but was taken off both for various reasons. She is always very dizzy, and her cognition has gone from bad to worse."

• Kim
• Taken for 1 to 2 years
• June 11, 2022

"Started March 2020. Did great on tysabri w severe weight gain, hair loss, gum pain, teeth dental issues, edema, thyroid nodules growing like crazy, extreme fatigue, had to take medical leave from work, can’t sleep, rashes, hard red flaky spots on skin, sweating, rib pain under breast unbearable they injected me w cortisone, I can’t work out, heavy breathing, legs feel heavy with little activity. Liver enlarged, trace blood in urine, kidney stones for the 1st time w/ 2 surgeries 5 months later more stones. No one recognizes me, skin is dry, nails brittle, red itchy eyes, joint pain, severe anxiety, headaches, heart palpitations, abdomen distention, random bruising especially on feet. Feet very hot & swollen, hands swell, constipated, nose bleeds dizzy. I have lost my entire quality of life, I was so active. Test come back “normal” but drastically not normal compared to bc I started. Poison."

• MSer
• Taken for 1 to 2 years
• April 9, 2021

"Ocrevus did not work well for me at all. After the third full infusion, I spent months in bed, vitals all over the place, pulse between 37 to 127, laying flat and with activity. SATing 70-80's with activity. Fatigue, weakness, dizzy, lightheaded, fainting, brain fog, and MS hug that felt like my ribs were cracking. Paralysis a week after infusion. In all fairness, it was a different type of drug for me. I do better with MS meds like Copaxone, Gilenya, and Tecfidera."

• K Mar...
• March 25, 2020

"I have RRMS, 37-year-old F. I have been on Ocrevus for 2 years now. Prior to this, I was on Betaseron and Tecfidera. This is by far the best medicine for me. It’s helped me. I take it every 5 months because I was crashing before I reached the 6-month period. It’s FDA approved that you can take it every 5 months if you are having that problem. It helps keep my leg pain, blurred vision, and fatigue at bay. Of course, I take medicine for those problems, but the combination of it all is a plus. What I don’t like is the infusion, at first, it’s hard on your body. The first treatment was horrible. The premeds help before treatment, which is Tylenol, steroids, IV Benadryl, and a toroidal shot. That combination 30 minutes before treatment works well. After the first treatment, it gets easier. Overall, it works for me, and I love it. I pray it works for others."

• Jessie...
• Taken for 2 to 5 years
• March 25, 2021

"I have PPMS and have been on Ocrevus for 2 years. I was previously on Copaxone but still had lesions develop while on it, and I absolutely hated the shots every other day. I always got a large welt and severe itching. Before that, I was on Aubagio, which made me feel awful. I do get some mild reactions with the Ocrevus infusions, like headache, itchy throat and ears, and rapid heartbeat, which usually lasts until the next day. I also get immediately sleepy from the Benadryl but then cannot sleep for a few days from the steroids. I am also constantly fatigued and have developed some skin lesions. However, it is all worth it to have my last 2 MRIs show no new lesions. This is the first treatment that I have been on that has done that. When I was first diagnosed, my doctor said I would probably be in a wheelchair in 10 years. Well, it’s been 7, and although I use a walker for balance reasons, I have had no further progression for the last 2 years on Ocrevus, which is what it is all about!"

• RBano
• Taken for 2 to 5 years
• September 25, 2020

"After beating my head against a brick wall with the drug company and my neurologist about the consistent weight gain from the Solumedrol that is a prerequisite for Ocrevus, I’m ceasing it. It’s just NOT worth spending a boring 7 hours in an infusion center. No progression of MS is fine, but the cytokine response was very unpleasant also, along with feeling absolutely drained for a month post-infusion. I still have symptoms that required treatment. All my life my blood pressure has been low, but on Ocrevus it’s now high enough to require treatment. I’m afraid the drug reps do way too good a job of marketing this awful substance."

• Mickey
• Taken for less than 1 month
• January 25, 2022

"It has been 5 years since ONE Ocrevus infusion for RRM …still not back to pre infusion status. Immediately after first infusion was in a severe TIA confused state. Went from walking w/ a cane to a wheelchair immediately after Ocrevus. Worst experience of my life. In last five years have been back to see my neurologist once. Absolutely LOST TOTAL FAITH in pharmaceutical Russian roulette called MS immune modulating treatments. Expensive, risky, not what they tell you. Didn’t work. Harmed me. No one cared. They only want to hear positive reports. It is all about the money. My experience has been treated with indifference. Good luck to all/"

• DM18
• March 7, 2020

"I am so happy that I came here because I needed to hear from someone who understood. 4 infusions, approximately 3 weeks ago. I have never felt worse in my life. Sudden aches out of nowhere. My mobility is not much better, not being able to control my bladder, and I am going every 20 minutes. Praying to God this time you make it without an accident. The 1/2 infusion, I felt great and thought, great, let’s pray this is the one. Not having the energy to do anything but Netflix, and Netflix, lol. I will be refusing that next dose and pray this is something that will wear off."

• MomBook
• Taken for less than 1 month
• April 3, 2019

"I had 2 half doses of Ocrevus, and I am now in my multiple sclerosis worse than I have been in 20 years. I am 69 and have had MS for going on 31 years. I had been on Copaxone for 20 years, and for over 15 years, it worked very well for me. Then I started going slowly downhill, so I switched to Ocrevus. I was due for my full dose 2 days ago, but I put a hold on it. I see my neuro tomorrow, and I will tell him I do NOT want it again. I have been off Copaxone close to a year, so I may ask to try it again. Between the Copaxone and starting Ocrevus, I had to wait because I was getting a shingles shot, and then I had to wait again because they kept sending the Ocrevus to the wrong hospital, so it has been a roller ride trying to get it. Now I just want Copaxone again. It was so much easier and no side effects."

• Erica
• Taken for 1 to 2 years
• January 12, 2022

"I have been on ocrevus nearly 2 years. Just had brain MRI. Shows new and larger lesions. It never helped with any of my MS symptoms (fatigue, pain, horrible insomnia, twitching, poor balance, anxiety, trouble with concentration, bad memory). If anything these symptoms have gotten worse.. And now it shows my MS has only progressed since taking Ocrevus. Extremely disappointed with this treatment."

• Phil
• Taken for 1 to 2 years
• February 9, 2022

"Funny how a number of positive reviews, question the bad ones out right. Sort of reads like a promotional campaign. Ocravus is garbage! It’s complete crap!! I don’t understand for the life of me how this stuff was approved. I was diagnosed in 2014. I was put on Aubagio and I was very steady for four years. By 2018 I started developing a limp. Caught up in all the promotional lies, I thought this garbage would fix my limp…. From 2018 until 2020 I did four infusions. The biggest mistake. I got worse in every aspect. Now I fully understand wtf MS is, and Ocravus was the driving force. I stopped taking it in 2020. I spent all of 2021 on nothing as I now use a scooter and can’t walk anymore. I’m trying to lower my EDS score through physical therapy, so that I could be eligible for Mayzent. Oh how I wish Mayzent was my next move from Aubagio. Sadly was not approved in 2018 in Canada."

• Fullt...
• March 24, 2022

"I was diagnosed with RRMS in 2015, 2 years later put on filgolamod ,was on that for 3 years with no new lesion but symptoms progressively worsening , re diagnosed with shadow MS and put on Octrevus. I had first 6 month infusion and greatly regret it . Before this treatment I could walk unaided, ride my horse and mow my lawn, now I can drag my feet for 15 meters at a time with crutches if lucky. I can't control my hands to cook any more and consider it a great achievement to make it to the toilet without wetting myself. I just did the 1 full 6 month treatment and now have been re diagnosed with SPMS, I am now just hoping that without this stuff in my system that I could possible hopefully get back to how I was before I took Octrevus."

• Silver...
• Taken for less than 1 month
• April 1, 2020

"I was diagnosed as an MS patient on Jan 24, 2020. I took cortisone injections for five days. Today, on April 1, 2020, I took my first infusion from Ocrevus. I was extremely worried after reading the reviews. However, it worked perfectly for me. I did not feel any of the side effects that were mentioned by the reviewers nor the ones mentioned online. My doctor has decided to divide the first infusion into two sessions. I will take the second infusion after two weeks. I will share my experience after having the second infusion."

• Beth
• Taken for 6 months to 1 year
• May 2, 2020

"Properly diagnosed PPMS last Sept. Had first Ocrevus two (split) treatments in November. Had MRI before first full dose, which showed new lesions on the brain. Infusion was 2 weeks ago and feel so fatigued, but will see what the next MRI shows. I’m going to keep persevering with the Ocrevus - this fatigue may be short term. I have not noticed any other difference, except I’m not tingling as much. I’m in Australia and it doesn’t cost anything."

• Daddy...
• Taken for 2 to 5 years
• June 7, 2020

"I work in the porn industry and I have MS, as soon as I started getting the infusions I immediately starting feeling signs of Erectile Dysfunction and now I can't control my bladder, I guess my porn career is over with because of this drug."

• Anonymous
• Taken for 6 months to 1 year
• April 24, 2021

"I was diagnosed on August, 2020, with PPMS at the age of 51. Ocrevus is every 6 months. I had half infusions on 9/16/20 and 9/30/20 respectively and my first full infusion on 3/29. No infusion reactions at anytime. I'm curious to know what all reviewers with negative comments chose to do? Get Ocrevus or not? I have seen no new lesions on MRI but feel my symptoms are much worse and I'm curious what everyone who responded negatively chose to do?"

• DTT
• Taken for 1 to 2 years
• December 10, 2019

"I just took my 4th dose of Ocrevus. I have had PPMS for 20 years now. I have done chemo/steroid treatments (those worked best for me) and many of the injections. I also used CellCept for a number of years but was prone to infection while on it. The first three infusions did nothing, but they didn't hurt either. Having PPMS and nothing happening is a good thing. However, this last infusion, anxiety and depression hit me like a ton of bricks. I hope it wears off because I take enough meds without adding antidepressants to it."

• Anonymous
• July 26, 2021

"My boyfriend was diagnosed in 2002, was on Rebif for a few yrs until he was switched from RRMS to SPMS and back then nothing else for him, when Ocrevus came out everyone raved about it. Thom had been without meds for 10 yrs so he was pretty anxious to start, especially with all the positive reviews. The first halves he started to experience more leg pain, after his 1st full dose he became so weak he was bedridden, could not roll over in bed, could not hold himself up in a chair, I would strap him in, all of his symptoms went into overdrive. His doctor and everyone from Ocrevus groups said give it time, he was on this poison for 2.5 yrs, along with all of his symptoms worse and the weakness he had hair loss, extremely dry flaky skin, skin lesions, bacteria infection in his nose, extreme constipation. It's been 19 months since his last infusion and thank God he is 95% back to his baseline.. All these doctors are calling it progression but in actuality it's this poison."

• Carlo...
• Taken for 1 to 2 years
• October 20, 2020

"Please read this if you are thinking of stopping your Ocrevus treatment. First half infusion (pre Covid): slight fatigue after it, had to work from home for a few days and sleep A LOT. Second half infusion: horrible side effects: off work for 10 days as a result. Spent my birthday in bed :( I told myself I would never use this drug ever again. Was not possible to switch so did not have any other choice than stick to it. First full dose infusion (about 10 months later due to COVID): I went to the hospital reluctantly, expecting the worst again... BUT to my surprise, I did not need any time off work after the infusion, I have felt more tired for sure, but nothing unbearable. So give it another try if you are hesitant. My MRI shows no new lesions and some have shrunken..."