Niraparib for Fallopian Tube Cancer User Reviews

• Mar...
• Taken for 1 to 2 years
• February 9, 2019

"I have been on Zejula since May 2017. I was put on Zejula after a recurrence of Stage 4 fallopian tube cancer. I started with 300 mg but experienced severe platelet issues after five weeks. The dose was reduced to 200 mg, but again had platelet problems after four months. I have been on 100 mg since November 2017 and have had no significant issues. I sometimes experience minor joint pain and fatigue. My CA-125 remains at 8-9. I continue with all my daily activities, including water aerobics, walks (4-6 miles), and a busy family and social life. For now, Zejula is effective and without significant side effects."

• Mar...
• Taken for 1 to 6 months
• July 2, 2020

"I was diagnosed with stage III-A fallopian tube serous carcinoma in 2018. After debulking surgery and chemo, I started taking 300 mg Zejula in January this year. Was debilitating until exhausted, and my platelets and WBC became very low after a month. Took a month off, then started taking 100 mg a day. Pulse rate high but controlled, occasionally very tired. My CA-125, which was initially 29, is now 3.2. Couldn't be happier or more relieved. Thrilled that I am able to take this promising drug!"

• BAa...
• Taken for 1 to 2 years
• November 16, 2018

"I have been on this drug now for a year after chemo as a participant in a clinical trial. I started out at 300 mg, then dropped to 200 mg after 6 months and now steady at 100 mg. I am not a large person, so they tell me that one of the findings in the test is to now dose by weight. When I first started, I took the drug in the morning and had nausea, so I started taking it before bedtime, which solved that issue. The biggest side effect for me has been WBC drop at a higher dose, so now just waiting to see if I can remain stable with WBC on the 100 mg. I am BRCA neg and CA 125 stays around 4. I am thankful there are clinical trials out there to try and keenly understand that each person differs in drug reactions."

• cre...
• Taken for 1 to 2 years
• October 5, 2018

"I was diagnosed with stage 4 fallopian and peritoneal cancer (BRCA1 positive) with an initial CA125 of 3490. After chemo, I was in remission for 2 years and then had more chemo for a recurrence. Afterwards, I went on Zejula and have been taking it for about 16 months. The initial dose of 300 mg per day gradually caused numerous side effects including fatigue, weakness, sleeplessness, increased blood pressure, back pain, and then finally I had to have a blood transfusion and go off the drug for a month. I resumed at 100 mg per day and all the side effects disappeared except the sleeplessness and blood pressure, and even those side effects were less severe. For the last 6 months, I have been on a dose of 100 mg just 3 times per week. We moved to Canada and Zejula is not available here, so I have been stretching out my supply. Throughout the 16 months, my CA125 has remained steady in the 7 - 8 range. I will soon be changing to Lynparza, which is available in Canada."