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Treximet User Reviews & Ratings (Page 3)

Treximet has an average rating of 9.1 out of 10 from a total of 92 reviews on Drugs.com. 91% of reviewers reported a positive experience, while 4% reported a negative experience.

Reviews for Treximet

Commonly mentioned side effects
  • Anonymous
  • January 18, 2012

For Migraine "I have suffered from severe migraines since I was about 13 years old and have tried every over-the-counter and prescribed medicine under the sun. NOTHING has worked like Treximet! This is truly a miracle. Within 30 minutes of taking it, my headache was completely gone, and no rebound headache! The only side effect I had was that I was very tired for about 5-6 hours after that. It is very expensive, but it is so worth the money."

10 / 10
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  • Anonymous
  • April 25, 2011

For Migraine "I get migraines-about 20 migraines a year and maybe 7 more that feel deadly: blurry vision, severe body tension, diarrhea, vomiting, feeling like I'm paralyzed, sobbing, etc. I've had them for over 15 years. I've been on many medicines with no improvement. My father gets migraines too, and when he had some success with Treximet, I tried it. Now, rather than hours of pain that occasionally brought suicidal thoughts, I have pain for 30 minutes, and then suddenly it's gone. I sit up against a wall, completely still for another 30 minutes before I feel confident that it's gone. There's no migraine hangover, and I'm fine to go to work again the next day. My only side effect has been dry mouth. Thank you, Treximet."

10 / 10
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  • Anonymous
  • April 16, 2012

For Migraine "Thank goodness for this medicine. Migraines are new to me. I tried Relpax before this one, and it did very little for me, even after taking two doses. I took this with my most recent headache, and it worked like a miracle. I didn't realize how bad I felt until I took this and started to feel better."

10 / 10
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Frequently asked questions

  • Anonymous
  • July 25, 2010

For Migraine "I typically take a DHE injection to treat my migraines. The downside is that it takes a couple of hours to rid me of the pain, and the symptoms during this cycle are horrible: nausea, nasal congestion, a very drugged, but not sleepy feeling. Treximet is great, it works within 30 minutes to an hour. Does not require sleep or other maintenance. Downside for me is that within 24 hours, the migraine is back!"

9 / 10
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  • Ste...
  • Taken for 5 to 10 years
  • October 13, 2017

For Migraine "I feel extremely nauseous and dizzy for about half an hour after taking these, but migraines make me feel nauseous anyway, so it's a small price to pay for getting rid of the pain. While the nausea and hot flashes persist, I like to think that the Treximet and the migraine are duking it out for superiority in my brain."

9 / 10
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  • Tip...
  • June 1, 2017

For Migraine "This was absolutely horrible. I had a migraine at work, and luckily, I work for a doctor's office. I took one pill since that's all that's in the sample. About 10 minutes later, I was sweating, my face was blood red, I was very, very nauseated, I felt weird, and I was dizzy. I ended up having to leave work and go lay down. Here we are, 12 hours later, and I still have a migraine. I am glad to hear it works for most, but I'd never take it again."

1 / 10
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  • Pat...
  • Taken for 5 to 10 years
  • February 28, 2018

For Migraine "I have used Treximet for about 5 years to treat my migraines. Best drug ever for relief. Works for me in about 10-15 minutes. I have tried Relpax and Imetrex with no relief. So glad you can get Treximet in generic now, even though I have good insurance. Outrageous cost without insurance."

10 / 10
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  • cna...
  • October 1, 2009

For Migraine "I am 30 and have had migraines since I was 14. My head has always hurt (to the touch) the day after a migraine. I did not experience that after taking Treximet, nor did I have any side effects. I absolutely love this medicine."

10 / 10
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  • Bor...
  • January 30, 2009

For Migraine "I've been battling migraines for more than a decade. Been through everything from aromatherapy to muscle relaxers to antidepressants, and so far, this has worked the best. Had a migraine last night and took a dose - in 20 minutes, I could breathe again. Started to get another one several hours later and took another dose, and it worked. Good drug that does what it says it will do."

8 / 10
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  • Anonymous
  • February 3, 2010

For Migraine "This is the best migraine medicine I have tried. It has been the only migraine medication to work on my migraines and with an immediate result. It works most of the time, but not always. Restated, I have never had a migraine medication work."

9 / 10
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  • Kim...
  • February 9, 2011

For Migraine "I love this medicine. It works! I too couldn't get it for a while because of how expensive it was. I was actually notified by Blue Cross that if I did a three-month trial of having my doctor write a script for the medications of Treximet separately (Imitrex pills and Naproxen pills) and see how those two separate medicines worked for my migraines, then if I still didn't get satisfactory results from these two medicines separately, then they would pay for the Treximet pills. I did the trial for three months, and I didn't get the instant results like the Treximet pills, also bad heartburn from the Naproxen. So I had my doctor report back to Blue Cross after the trial three-month period that I wasn't getting the results I wanted, and they started covering it."

10 / 10
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  • Anonymous
  • April 19, 2011

For Migraine "Treximet is the only medicine that I have tried so far that will get rid of my headaches. I get 7-10 migraines a month, and they can last for days. I have found that with Treximet, I at least get a 12-24 hour break in my headache clusters. My muscles do feel funny (heavy and weak) after I take it, but that is the only side effect I have noticed. My only contention is that my insurance only covers 63 pills/180 days, and that I can go through more than that."

10 / 10
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  • Ahh...
  • September 18, 2016

For Migraine "Yes, the migraine went away. It's the side effects. Appetite immediately went down the drain, irritable, most of all itchy. Itchy all over like crawling skin. Even worse, the itching focused on my manhood, if you catch the drift. Losing my mind... I don't recommend it."

4 / 10
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  • Bea...
  • August 1, 2011

For Migraine "Amazing - gets rid of a full-blown migraine in 30 minutes. I call it my miracle pill. I do experience drowsiness and a bit of tightness around my shoulder area, but when it passes (within 30-40 minutes), the migraine is GONE."

10 / 10
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  • Aut...
  • Taken for 5 to 10 years
  • January 25, 2020

For Migraine "This medication is a lifesaver. It is the only medication that works for my migraines, and I’ve tried tons, including Botox. Love this med. I have not experienced any side effects from this medication."

10 / 10
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  • Anonymous
  • August 26, 2011

For Migraine "Expensive for 9 pills, but highly effective. Gets rid of a migraine in 1 hour and doesn't make you drowsy. I would say there is an added heaviness to your brain and muscles (you feel a little slow), and you can't exercise right after you take it or it will give you palpitations. I haven't noticed any other side effects, and compared with having a migraine, Treximet gets me back to normal in 3 hours (side effects are gone in 3 hours)."

10 / 10
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  • Rod...
  • Taken for 5 to 10 years
  • November 3, 2018

For Migraine "Treximet is my wonder drug. I’ve suffered from migraines my whole life, and this is the only drug that offers fast relief, and I can get back to my day without much issue. Side effects are minimal, but I do feel a little “jittery” after I take it. I use a mail order service to get Treximet, and it is a huge cost saver!"

10 / 10
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  • Fem...
  • January 14, 2012

For Migraine "On average, I get 4-6 migraines a month, and this is by far the best migraine medication I have tried! Within 10-20 minutes, the migraine is completely gone after taking just 1 pill. I turned to a prescription strength after OTC medication, heat/cold packs, sleep, etc. stopped working. So far, I haven't had a recurring migraine either, which usually happens to me after taking over-the-counter medicines."

10 / 10
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  • cha...
  • October 26, 2011

For Migraine "This is the best by far. The pain is gone in 45 minutes to 1 hour usually. Unfortunately, my insurance doesn't cover it, and it's about $30 a pill, so unless I can get a coupon or samples, I have to take Imitrex, which is hit or miss for me and makes me feel funky for hours after. I haven't noticed any side effects from Treximet."

9 / 10
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  • Hea...
  • Taken for 10 years or more
  • March 12, 2022

For Migraine "Tried multiple meds for migraines throughout the years, and this remains the best. Cost was too much, and my Dr. started prescribing Sumatriptan and OTC Naproxen. I take one of each, which equates to about 1/2 a Treximet because a full dose gave me some uncomfortable side effects, granted, they were better than the migraines. Super cheap and works exactly like Treximet. I absolutely don’t understand why more Drs don’t do this, it’s the same ingredients, and you can almost get the milligrams the same. Starting Eletriptan for the first time to see if I can get them under control a little more, I also have gotten some relief with dry needling."

10 / 10
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  • Aud...
  • January 7, 2011

"This medicine zapped the migraine away quickly. I felt 'up.' Slept lightly with crazy dreams. Ten hours later, I had a bad 'coming down' experience. Paranoid, heart racing, bad trip, dry mouth, and initial tingling minor. This medicine did work, but I didn't like the negative side effects it had on me. You may not have any side effects. Be aware of your body's reaction."

8 / 10
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  • Anonymous
  • February 24, 2011

"Treximet works great! I know others say it does not work after the migraine starts, but for me, it does. I have chronic migraines and have to take an anti-depressant drug to control it daily. However, if I do get a migraine, Treximet knocks it completely out in about 20 to 30 mins. I love this product, but like most people, I find it very expensive but worth it. I may try taking half a pill to see if I can make it go further."

10 / 10
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  • Mig...
  • Taken for 6 months to 1 year
  • January 31, 2013

For Migraine "I took 1 Treximet pill in January of 2012 and a 1/2 the following day. My migraines almost faded away for the last year. Throughout 2012, I still had small achy headaches, but nothing like before I put Treximet in my system. It is now a year later, and I had my first migraine last week. I still have the same prescription from last year, so I don't have to buy any more. I cut my caffeine to almost nothing and got lots of natural sunlight. My headaches are fading out, but I am going to take my yearly pill. I think this pill is worth every penny. Take this pill and find something to keep you busy."

10 / 10
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  • Anonymous
  • June 28, 2009

For Migraine "I take it for my stress migraines. Gets rid of my headache but causes my jaw to feel tight."

9 / 10
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  • Daw...
  • Taken for 1 to 2 years
  • December 7, 2013

For Migraine "Best headache medicine I've ever taken. The only one that takes care of a migraine well enough that I can still function. It's expensive, but worth every penny."

10 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.