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Metoclopramide for Migraine User Reviews (Page 4)

Brand names: Reglan, Gimoti, Maxolon

Reviews for Metoclopramide

Commonly mentioned side effects
  • Kit...
  • November 5, 2016

Metoclopramide "I as well had a severe migraine that was 2 days old. Went to ER and she said, let's try Reglan and Benadryl. I said do whatever. Within 20 seconds of the IV, I literally froze. My heart was beating insanely, my brain was doing 100, and my body froze. I couldn't move if someone pointed a gun at me. I tripped out so bad. She tried talking to me and I didn't even answer. So she said the lights would turn off and get some sleep. I finally could move my fingers to text my then boyfriend, please come lol. I was pregnant years after, and with that came migraines. Went to my doctor and she said, let's try Reglan... I stopped her and said like hell! She just did Benadryl and Tylenol 3 pills. Good lord. That drug is for the devil, I'm sure."

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  • Red...
  • Taken for less than 1 month
  • April 30, 2014

Metoclopramide "Had a migraine for three days that escalated and went to the ER. They gave me Reglan with saline. Not only did it do NOTHING for my headache, it put my Restless Leg Syndrome into overdrive, affecting my entire body, but wouldn't prescribe anything for that. They attempted to flush it out with more saline to no avail. They eventually gave me Fioricet, and that at least helped, though didn't stop the migraine."

2 / 10
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  • Mar...
  • July 26, 2019

Metoclopramide "About a year and a half ago now, I had just had a tooth extracted that was causing a severe headache. I made the mistake of going to the ER. I was administered Benadryl and Reglan and had a horrible reaction with my heart racing. The ER tried to imply that me describing the negative effects of the drug was an 'anxiety attack' rather than side effects from the drug."

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  • Anonymous
  • June 5, 2019

Metoclopramide "OMG, worst medicine mixture ever!!! I’ve had this terrible stuff 2 times. The first time, I went to the ER for an awful migraine, and they gave me Compazine, Reglan, and Benadryl, and immediately I started feeling very tired but restless and anxious at the same time. I wanted to sleep, but I couldn’t because I felt like I just wanted to run out of there and just go home! It’s the worst anxious feeling I’ve ever experienced. So, the next time I had a migraine, they wanted to give me that, and I thought, well, maybe it was just a bad reaction last time or something, but NOPE! I had the same feeling, and they wanted to do an MRI on me because of other neurological symptoms I came in with, but since I was feeling so awful, I just told them, nope, I want to be discharged. I’m definitely going to tell them next time those medications I cannot tolerate, and I refuse them."

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  • Nan...
  • March 13, 2016

"I've never written any reviews on the internet before, but after my experience in the ER last night, I googled the effect of Reglan and Benadryl on headaches just to see how others react, and I feel better that many reacted like me, so I'm not crazy. So they gave me Reglan and Benadryl IV push. I was just ready for relief. Little did I know everything started moving so fast, I was scared for my life. My husband was in the waiting room with our sons, but I started texting him to come back, but I couldn't even compose a text. The door was shut, and the lights were dim, and I had the worst anxiety attack. I've never felt like that in my life. Called for hubby, begged him to ask the doc to let me go... which he did. Eventually, I felt better at home."

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  • Sop...
  • January 8, 2016

"I'm 18 and had a lumbar puncture done on 12/29. I've had a severe migraine ever since, so on Tuesday, Children's Hospital told my mom to take me to the ER. Once there, they gave me this, and let me tell you, from someone who suffers from terrible panic attacks, this was genuinely one of the worst ones I've ever had. Ten minutes in, I started feeling restless and started moving and moving because I literally wanted to rip the IV out of my arm and run out. I got up and I started sobbing, and I felt like I was going to die. I really wanted to just rip the IV out, and I was terrified that I was going to. Mom had to call a nurse, and they gave me Benadryl, and that knocked me out. A day later, though, my severe migraine is back. Not worth it, guys. Nope."

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  • Ada...
  • November 12, 2016

Metoclopramide "I was given a cocktail of Reglan and Benadryl for a migraine at the ER. Within no time, the migraine was gone, but a few minutes later, I got an awful panic attack. I thought I was going to die. I wanted to rip the IV out of my arm. When this happened, my boyfriend got the doctor, and she said this happens to about 50% of people. Since I'm so small, they started with only a half dose of Benadryl to make me sleep, but after I couldn't sleep because of the side effects from Reglan, they gave me the other half dose. I am lucky to have had my boyfriend there to get a nurse and calm me, and I'm lucky they could give me more Benadryl. I will not take this medicine again. If you have to take Reglan, bring someone to help you, but I suggest not taking this at all."

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  • Che...
  • January 8, 2017

Metoclopramide "Visited the ER due to an intense migraine lasting 7 days with 4 impacted wisdom teeth coming in. Face swollen, migraine, and intense anxiety went to a different hospital and was hoping for something that worked, but got the Reglan/Benedryl cocktail which made me freak out like an idiot, and I cried for anxiety meds when a new doctor came in and denied me anything else and called me a pill popper, although the only meds I'm taking are for my teeth pain (antibiotic and a steroid) and also continued to be rude while still having an outrageous migraine. Home now... hours later... with a migraine still......"

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  • RAC...
  • Taken for less than 1 month
  • November 19, 2022

Metoclopramide "Reglan caused me to experience major anxiety and panic attacks within minutes of receiving it via IV. Made me feel like I was dying. The anxiety attacks took a few months to subside. Horrible drug, wouldn't recommend to anyone."

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  • R G...
  • Taken for less than 1 month
  • June 11, 2016

"Horrible. Went into the ER for a 2-week-long headache. Never saw a doctor the entire time I was there, but 3 nurses and a PA. One of the 3 different nurses came in to finally administer the 'cocktail' from hell. Now I told them I suffer from anxiety, yet I was told it would only cause a warm sensation of being flushed. Well.... that's bulls**t. After the first medication, Benadryl was administered, I felt it cold going into my arm. Then the second, Reglan, which was shoved in my IV rather fast. The nurse asked me ... how are you feeling? I'm um um ok.... and BAM it hit me! I felt a burning sensation across my chest... my eyes bugged out... my heart was beating out of my chest... I turned pale... I wanted to rip out my IV and run. And after she did... I ran out."

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  • Anonymous
  • July 16, 2017

Metoclopramide "I've been to the ER for migraines too many times to count and have been given every kind of drug that can be given. I woke up this morning with a horrific migraine and vomiting, and off I went. They gave me the Reglan/Benadryl combo, and within less than a minute, the pain was gone. I COULD NOT BELIEVE IT! I've never had anything work so well and so fast. I went home and slept for four hours afterwards. I'm so glad they decided to try this with me."

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  • Mar...
  • Taken for less than 1 month
  • June 11, 2019

Metoclopramide "6/10/19 I received the migraine cocktail for the first time. The doctor was very careful to push the Reglan slowly into the IV. At first, I felt fine, but once she left the room, I got hot, sweaty, and anxious. I had full-body tremors, sweat through my clothes, and felt like I needed to rip the IV out and run. My severe migraine is gone, but I would recommend not trying this medication if you already have anxiety or if you’re sensitive to medications."

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  • Anonymous
  • August 11, 2018

"The reason so many of these reviews are negative, with reports of anxiety, is because the Reglan wasn’t mixed into an IV fluid bag and instead pushed. The nurses in all those ERs should have known not to push IV Reglan. Always ask to check drug interactions with a care provider that can’t clearly state the possible side effects. Also, they should just know."

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  • Mom...
  • Taken for less than 1 month
  • October 24, 2015

Metoclopramide "Reglan, given in a small dose in her IV, takes my 16-year-old daughter's migraine away. She is a chronic sufferer and has been for many years. She has been hospitalized for migraines. In an hour, she is back to normal but sleepy from Reglan, Toradol, and another anti-nausea med. I'm going to see if she can take Reglan at home in pill form to save a trip to the ER."

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  • Ted...
  • January 23, 2017

Metoclopramide "I went to the ER with a migraine I had had for about 4 days. I was given this medication. I was in so much pain. I was so anxious. I told them I was still in pain. My blood pressure was going up and down. I will never let them give this to me again. I was there 6 hours and left with no relief. I felt like I was tortured. Reglan and Benadryl."

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  • Anonymous
  • May 8, 2017

Metoclopramide "Jim. I've had migraines for over 60 years. Currently, they are frequent but not debilitating as in the past. I'm an anomaly, having migraines at my age (77). My doctor prescribed Reglan pills with 6 hours between doses. Sometimes it helps, sometimes not. It's not my go-to med, but I use it because I don't want the others sometimes. I suspect high doses given quickly can cause problems some have. Maybe my doctor, a stroke specialist who also has migraines, may be better informed than those prescribing high-dose quick injections. There are emergency rooms in my area that I wouldn't let someone take me, even with a heart attack. Remember, 50% of docs were in the bottom half of the class. You don't know where your doc was."

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  • Sam...
  • February 27, 2019

Metoclopramide "I was in the ER last night for a severe migraine attack. The doctor asked what I normally get, and that's Toradol, Zofran, and steroids through IV. They came in with this Toradol, Reglan, Benadryl mix. Literally, 2 minutes after the meds were administered, I felt the need to jump out of the bed and just go home. I was burning up inside, restless, and still had the headache. So when I see other people posting almost the exact same thing, I totally get it. The National Headache Society did a study, Benadryl is actually one of the drugs NOT recommended to treat migraines. I was told Reglan treated the 'pain.' Nope, it actually just controls the nausea by getting your stomach to empty/process the contents faster. I had the same migraine when I woke up. Now the Toradol I know helped, it usually does to some degree. But getting a steroid shot/injection is usually what keeps the migraine from returning. Personally, I just don't think the doctor had a lot of knowledge regarding the treatment of migraines."

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  • Boo...
  • January 8, 2018

Metoclopramide "Twice now I've been given the 'cocktail' in the ER for migraines. The first time, I was ready to get the hell out of the hospital as soon as the headache was gone, I was so ready to go. Yesterday, I flipped out SO badly! I was screaming, begging for someone to help me, that I was losing my mind. My mom had to climb onto the bed and hold me while I freaked out. They finally gave me some Atarax to calm me down. Atarax in itself is a whole new story."

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  • ast...
  • Taken for less than 1 month
  • March 27, 2023

Metoclopramide "Went into the ER for a migraine that was bothering me and had me leave school early. They didn’t explain much about the drug, but they gave it to me anyway with a combination of Benadryl. It was the worst experience I’ve ever had in my life. I was feeling anxious a few minutes after taking it, but I wasn’t expecting it to become the most horrifying and insufferable experience in my life. I felt like I was coming out of my skin and wanted to rip the IV out and the skin off my body. I had a panic attack that lasted a long time and couldn’t stop freaking out. I remember looking at the nurse and asking her, “What did you do to me?” as extreme paranoia and panic flooded through my mind. A doctor came by and offered Ativan to help. I couldn’t trust them and declined a few times, even though I am really into pharmacology and knew it would help, but my paranoia made me feel like they would give me something else and kill me. I ended up taking it, and it helped."

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  • Mig...
  • Taken for less than 1 month
  • September 10, 2017

Metoclopramide "Went to the hospital last night for flu-like symptoms. While I was there, I experienced a sudden migraine. When I told the Dr., he decided to treat me with a cocktail outside of my usual. He gave me Reglan, Toradol, and Benadryl. As soon as the nurse began to push the meds in my IV, I felt the worst burning sensation ever! After all 3 meds were in, I began to feel closed in, constricted, and overall worse. The nurse ran and got the Dr., and this is when he decided to reveal that the Reglan can make you feel very anxious. He said it should go away in 10 mins or so, and it did, but I will never allow them to give me this medication again. I literally tried to rip the IV out of my arm because of it."

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  • SMJ...
  • Taken for less than 1 month
  • March 1, 2016

"About 2 weeks ago, I had a migraine that lasted for about 3 days until I finally went to the ER. When I was seen, the doctor gave me a mix of Reglan and Benadryl in an IV, and boy, was that the biggest mistake of my life. At first, I felt silly and sleepy and even laughed a little. Then the next thing I know, my eyes are wide because my heart starts racing like crazy! I already suffer from anxiety, I wish she would have mentioned the side effects before she injected me with the meds. I would have never taken it via IV. I thought I was gonna die! I called the doctor back in and she told me to just calm down. My heart rate finally calmed, but then I started shaking. Then came sleep. I woke up and felt a little better. It made me feel depressed a few days later. Traumatized forever."

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  • Tha...
  • Taken for less than 1 month
  • November 11, 2019

"A few years ago, I had a migraine for 8 days straight. Worst migraine ever. It was blinding, nauseating, painful even at the slightest movement or sound. Went to the urgent care and was given a dose of the combo of Reglan and Benadryl. Worked so many wonders. So thankful for the Reglan. No bad side effects, and the migraine was soon gone."

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  • Gen...
  • Taken for less than 1 month
  • July 26, 2019

Metoclopramide "Doctor prescribed this for migraines. Immediately after taking the first pill within an hour, I jumped out of bed and was restless, shakes, had severe anxiety, trembles, and felt like I was going to die. This lasted days - I told my next doctor this, and she then told me that some people do have this reaction. I will NEVER take this again and do not recommend it."

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  • Bey...
  • Taken for less than 1 month
  • February 23, 2023

Metoclopramide "I went to the ER for a migraine that was lasting several weeks. They gave me Tylenol and Reglan (after having told them of my history of anxiety). Within minutes of the Reglan, I started to have the worst panic attack of my life. I couldn't keep my legs still, my whole body kept jerking, I wanted to rip out my IV and run, I was crying loudly, and I was pulling on my hair. My husband said I looked like the Exorcist. The ER doctor said that can happen if the nurse pushes the meds too quick, but the nurse denied doing that. They gave me a half dose of Benadryl, which did nothing, followed by another half dose. About an hour later, I was exhausted, no longer freaking out, but still occasionally twitching. Never again. I list it as a med allergy now. My anxiety is still increased 7 months later, and I don't know if this is to blame."

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  • Nos...
  • Taken for less than 1 month
  • August 19, 2019

Metoclopramide "My son has hemiplegic migraines. We just had our 3rd ER visit. First time getting Reglan in the cocktail. He began shaking uncontrollably with chills and had almost muscle spasm jerks. We had no warning of possible side effects, so obviously he was scared, increasing the side effects. The nurse said it is a mild, common, allergic reaction to the drug. He was treated with an additional IV dose of Benadryl and began to settle fairly quickly. Know that this reaction is a side effect."

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.

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