Metoclopramide for Migraine User Reviews (Page 3)

• K8T...
• December 8, 2017

Metoclopramide "I had a severe migraine for several days. Norco and Fioricet weren't even touching the pain. Finally, I gave in and went into the ER. They gave me what they called a cocktail including Reglan and Benadryl. Nothing that was actually intended for pain, but I was willing to try anything, so I didn't comment. That was the day I experienced my first ever panic attack. I couldn't vocalize what was wrong, I was hot, thrashing, and grasping at my IV, my heart was racing, and I thought I was actually dying. It sounds so dramatic, but there really aren't words to describe the feeling of the moment that you believe your life is ending. Those of you who suffer from panic attacks, you have my respect and sympathy. Traumatized from Reglan. Never again!"

• csw...
• October 20, 2014

Metoclopramide "The first time I ended up in the ER for a migraine was 10/5/14. It started at 11 AM while I was at work and only progressed throughout the day. I wasn't able to eat, and when I finally did, I threw it up within minutes. I took 1650 mg of Tylenol between 11 AM and 10 PM, applied heat to my neck (which usually helps me), took a hot shower, and laid in a dark room... NOTHING helped that I tried. It brought me to tears, and I couldn't get comfortable or fall asleep... it felt worse while lying down. I called my mom at 10:45 PM and asked her to take me to the ER. I was given Toradol, Benadryl, and Reglan, and I felt no pain and was asleep within minutes... I slept the majority of the following day, but it helped!!!!"

• Anonymous
• Taken for less than 1 month
• January 6, 2017

Metoclopramide "I went to the hospital for a bad migraine that at the time lasted 3 days. The worst I've ever had. They gave me a cocktail of Reglan and Benadryl through my IV. Within a minute, my chest felt like it was burning. I couldn't breathe, my blood pressure skyrocketed. They administered the Benadryl and still no help. My chest felt heavy, and I thought I was going to die. I couldn't move, talk, or anything. They put oxygen on my face and called the doctor in to see me. He then administered Valium STAT, then I began to calm down. They said that the nurse administered the Reglan too fast, causing the side effects. After about 4 hours in the ER, they sent me home. At least I left with the migraine gone! But never again will I allow Reglan to be administered to me!"

• Ebb...
• Taken for less than 1 month
• April 21, 2018

Metoclopramide "I will never in my life allow this to be administered to me ever again in life. On 04/20/2018, I went to the ER for a severe migraine. The RN gave me a cocktail of Toradol and then the Reglan. About 30 seconds later, the nurse walked out, and I began to experience a strong, intense feeling of fear, anxiousness, and anxiety. I wanted to rip the IV out of my arm and run all the way home. I never want to feel like that again... NEVER!!"

• Anonymous
• December 1, 2015

Metoclopramide "Lord! This was like a death experience for me. I am scarred for life. I have been feeling sick for about 4 days in which I acquired a sore throat, earache, stiff neck, super swollen lymph nodes, fever, and the worst headache ever. After the initial test that ruled out negative for meningitis, mono, and strep throat, they decided to give me a cocktail of Reglan and Benadryl through my IV. Within seconds, I felt a burning sensation as well as sleepy, so I thought I would be okay. Boy! Was I wrong. My heart was racing at 150 bpm. I lost my voice, was super jittery, and felt like I was going to die. The nurse told me to relax, she looked worried. I wanted to pull my IV off. I told her to get it off, and she insisted that she would give me Toradol to help calm me. :("

• Anonymous
• April 7, 2014

Metoclopramide "Went to the ER on Saturday, got Reglan, Benadryl, and Toprol, along with a bag of saline. Yummy combination, knocked out my migraine and me. Slept for an hour in the hospital, then another 4 at home. I'm still wiped out, but after a doozy of a migraine, I am exhausted for at least 5 days post. Almost like a hangover."

• Nel...
• March 18, 2016

"I thought I was the only one this anxiety attack happened to. I went to the ER for a migraine. I was given Benadryl, Reglan, and Toradol. I felt a burning feeling, then a sudden high. Next thing you know, my heart started racing. I was so scared. I was shaking from being extremely cold. When I called the nurse, he looked at me as if I was crazy. I prayed myself to sleep. Horrible experience."

• Anonymous
• October 9, 2010

Metoclopramide "I was just given Reglan this morning at the ER but don't think they combined it with anything but saline. Usually, I get the physically 'hyper' feeling but with mind exhaustion with Dramamine or Benadryl. Those medicines make me feel like all my muscles need to be repeatedly stretched and like they are itchy on the inside. Luckily, I did not get this feeling at all today with just the intravenous Reglan. Even managed to sleep through half the drip. Only bad thing was that it was really cold going into my arm... my whole arm felt numb. Also, don't know if it is common or not, but was starving 6 hours later and ate more in 1 sitting than I ever before (I'm sure I will regret that tomorrow)."

• No ...
• June 17, 2016

Metoclopramide "Had a myelogram on a Friday. By Sunday, I had the worst headache in my life! Tried to get through the pain, but by Monday morning, I was told to go to the ER. I told them I had a spinal headache, not my typical migraine. They gave me IV fentanyl, which calmed it for 20 minutes. They then gave me the 'cocktail' of Benadryl, Reglan, and Toradol. Within minutes, I was shaking violently and couldn't control it. It made me so nauseated. I thought I was going to either have a seizure or a heart attack! It didn't give me any relief at all-not even sleepy. After several unsuccessful pages to anesthesia for a blood patch, I said I had enough and wanted out of there (after more than 6 hours in the ER)."

• Mah...
• March 31, 2015

Metoclopramide "I don't have a history of migraine, but I had severe headache for 3 days, so I went to the ER. After doing some scans, they gave me Benadryl, Toradol, and Reglan by IV. As soon as Reglan was injected, I had a severe reaction to it within seconds, and I couldn't move, I couldn't talk, I was literally paralyzed. I could hear people talking, but I wasn't able to respond, and my heart rate went to 150 bpm. It was the worst feeling ever. They had to give me an antidote to reverse the effects, but it still took almost 3 hours for me to actually speak again. After that day, I personally do not like Reglan and how dangerous the side effects can be."

• Kal...
• May 22, 2021

Metoclopramide "I suffer from hemiplegic migraines and had a very bad attack yesterday late morning. I went to the hospital where I was given an IV push of Benadryl, Toradol, and Reglan. As soon as she started the IV and walked out of the room, I had a horrible feeling come over my whole body. My legs felt like they were on fire, and I felt as if I was going crazy. I tried to relax and shake it off, but the feeling wouldn’t go away, and I became dizzy and almost delusional. I called my wife to tell her what was going on, and she told me to hit the call button, so I called the nurse back in and told her how I was feeling, and she said the Reglan has that effect on some people. She pushed Ativan to counteract it. It was a scary feeling."

• Jad...
• March 6, 2017

"I'm an ER nurse. We use a cocktail of 20 mg metoclopramide with 25 mg diphenhydramine. That's 2 vials of Reglan and 1/2 vial of Benadryl in a 250 mL NS bag. Reglan is the primary medication in this cocktail, Benadryl is given to reduce the side effect known as akathisia. Both Reglan and Benadryl cause drowsiness, hence, only half a dose is given. 250 mL saline bags are used so we can control the rate of flow of the medication (to infuse slow over 20 minutes, we don't use an IV pump with these medications). Ketorolac is optional. If not given correctly, in most cases infused as a bolus/wide open. This is where the problem occurs. I would say it has a success rate of 80%. I've seen akathisia just twice, I give it cautiously every time."

• Kat...
• Taken for less than 1 month
• September 5, 2017

Metoclopramide "Do not take this medicine. One-time IV dose. Causes nervous system damage. First Parkinson's side effects, then anxiety after five months not gone. Possible sensitivity to other medications. Horribly traumatic. Couldn't work."

• Qui...
• September 22, 2017

Metoclopramide "Given IV with Toradol & Benadryl. My headache went away almost immediately. Soon after that, I started shivering and trembling. I dismissed it, thinking I was just cold because of the hospital temperature & the IV fluids. I also had to pee so bad that I unhooked it myself because I could not wait for the nurse to come in and help me. I was so restless and anxious that I drove home, knowing the nurse told me to call a ride, but it's like I couldn't control the urge to just make it home and go to bed. I didn't realize that all of those symptoms were side effects of the medicine until I got home & started to tremble more & was unable to sleep. Since then, I've been having panic attacks & anxiety, muscle stiffness & twitches. DO NOT TAKE."

• Kam...
• Taken for less than 1 month
• June 22, 2019

Metoclopramide "OMG, where do I begin? Was in the emergency room for severe migraine and nausea. They gave me this drug through my IV. Never again. I began to sweat, I started cursing and screaming, I was so anxious and delirious. It was a terrible experience. I feel like I needed to just run out of the hospital. Do not recommend."

• Jc1...
• Taken for less than 1 month
• April 26, 2020

"I went to the ER with a hypertensive crisis. Once they got my BP stable, my severe headache was still very persistent, so the doctor prescribed metoclopramide and Benadryl. Unlike many others here, I had absolutely no anxiety to the Reglan. My headache was alleviated within 15 minutes, and within a few hours, I was able to go home."

• Anonymous
• August 21, 2009

Metoclopramide "Like the other anonymous user, I went to the ER with a migraine. I received this medicine and Benadryl (Diphenhydramine) intravenously. The side effects were intolerable. Within minutes of injection, a combination of agitation, nervousness, and anxiety overwhelmed my already throbbing head. I felt trapped, as if there was no escaping the discomfort of the side effects. I gave this a 3/10 because it still prevented me from throwing up after I already had several times. It works, but I won't ever use it again. I know it wasn't the Benadryl, as I have taken it since without incident."

• NuJ...
• November 10, 2015

Metoclopramide "I've had a headache for a little over a month, followed by nausea. However, yesterday there was some pressure with it, so I went to the ER. At the ER, I was told that I would receive a migraine cocktail, which was Benadryl, Reglan, and IV fluids. Not knowing what to expect, I accepted. As soon as I was given the medicine through my IV, I immediately began to feel jittery. My legs started shaking, it felt like something was crawling on me, and then I got extremely sleepy. I kept falling asleep, but every time I woke up, I had some serious anxiety. I never want to experience that feeling again. And what do you know, today my head is starting to hurt again."

• Bea...
• Taken for less than 1 month
• June 26, 2022

Metoclopramide "I'm not kidding when I tell you this medication made me feel a way I never want to feel again. I have since listed this medication as an allergy because I refuse to go through what this medication put me through. I was losing it inside the ER after being given this. Could not sit still and wanted to rip my IV out. I would have rather felt a migraine/nausea than be given this. Would not wish this medication on my worst enemy. Very jittery and uneasy throughout your body. Please be advised."

• Mac...
• April 12, 2013

"I too received a Reglan (metoclopramide) with Benadryl IV when treated in the ER. I was warned that this medication would make me extremely drowsy, and it did. I also have to say I felt an extreme restlessness almost as instantly as I felt the medication reach my veins. I remember my husband holding my hand and rubbing my back and telling me to settle down because I became antsy. I was thrashing a little and tossing and turning in the bed. I think we experience this because the medication comes on so strongly, and your first instinct is to try to fight how you're feeling, and it gives you extreme fatigue, which I believe gives a false sensation of dizziness and that you're falling, which I believe is what causes the anxiousness and restlessness."

• Bla...
• Taken for 5 to 10 years
• May 4, 2015

Metoclopramide "I was diagnosed with 'Chronic Migraine Disease' 18 yrs. ago. I have tried too many medications to list. Almost all of which have not worked for me. About 9 yrs. ago, during a trip to the emergency for a migraine, I had the worst nausea. I was given Reglan for the first time. Not only did it stop the nausea, it calmed my migraine down! I wasn't even given any Dilaudid. I couldn't believe it! I was later prescribed Reglan along with Maxalt. This combo worked the best for me. However, my doctor quit using Maxalt. So, while searching for new meds, my doctor gave me a prescription of Reglan to at least help with the nausea. Not only did it help with that, but if caught early enough, it would stop my migraines. I love Reglan!"

• Anonymous
• April 4, 2017

Metoclopramide "I'm surprised to see all of the negative comments about the Reglan, Benadryl, Toradol combo. It's been a lifesaver for me! When I've gotten a terrible migraine that I couldn't shake, this was the only combo that could help me. I never experienced any bad side effects like the ones people have mentioned. I've been given it several times while at the hospital, and it has always gotten rid of my migraines without really any negative side effects. The only thing is that it makes me really sleepy."

• AAa...
• Taken for less than 1 month
• June 11, 2017

Metoclopramide "Went to the ER for high blood pressure and was having a bad headache as well. Was given Reglan cocktail and afterwards I have had the worst anxiety ever. I wanted to rip the IV out of my arm and run out of there. I will never let them give me those meds again."

• Kit...
• October 27, 2019

Metoclopramide "I went to the E.D. 2 nights ago for a massive headache, the worst headache I have ever had in my life, and I was miserable and dry heaving. When I finally got pulled back, they gave me the 'headache cocktail' with Reglan, Benadryl, and Toradol. The nurse started taking the blood pressure in the same arm as my IV. While it was squeezing my arm, it was shooting pain in my arm. The fluids were painful in my arm, and I kept begging for them to take them out. I had a massive panic attack and couldn't keep my legs still. I started feeling like I needed to get out of my own skin, and my clothes were strangling me. I started begging for them to let me leave because I HAD TO go. It took about 30-45 min for me to actually calm down. My headache went away, but I freaked out both my mom and my boyfriend. It was one of the worst experiences of my life. While I was leaving, the doctor was like, 'Oh, yeah, one of the medicines can wind you up and give you anxiety like that.' Thanks, glad you tell me this now."

• Lay...
• November 30, 2016

"I went to the ER with a terrible migraine. No warning of side effects, and while I was anticipating relief from the migraine, the complete opposite and possibly even worse happened. It started with a little fidgeting and not being able to get comfortable in the hospital bed, and then I went from 0 to 60 as far as a freak-out. I have never felt like that before in my life, and it was quite possibly the worst feeling ever. I was alone in the hospital because my husband had to be home with the kids, and it was so frightening. I wanted to crawl out of my skin, my heart was racing, and I was clawing at my face, and I had uncontrollable full-body movements. I wanted it to stop, and all I kept asking for was help and for someone to make it stop. NEVER AGAIN!"