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User Reviews for Maprotiline

Maprotiline has an average rating of 9.4 out of 10 from a total of 17 ratings on 93% of those users who reviewed Maprotiline reported a positive effect, while 7% reported a negative effect.

Condition Avg. Rating Reviews Compare
10 reviews 78 medications
Major Depressive Disorder  
4 reviews 47 medications
Panic Disorder  Off-label
3 reviews 19 medications
Summary of Maprotiline reviews 9.4 17 reviews

Reviews may be moderated or edited before publication to correct grammar and spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest in the medication will not be published. As reviews and ratings are subjective and self-reported, this information should not be used as the basis for any statistical analysis or scientific studies.

Reviews for Maprotiline

Waiting · Taken for 10 years or more October 21, 2020

For Major Depressive Disorder: “Maprotiline is the only anti-depressant that is rated a 10 for major depression, yet it has been taken off the market. Has anyone found anything comparable to it? I haven't. Are you able to get it in Canada now?”

10 / 10
sue August 31, 2020

For Depression: “I've been taking maprotiline for 26 yrs. Everything was going great until Mylan stopped making it. My body was so use to it cannot stop taking it. I keep calling Mylan been getting the run around. I've started getting it overseas, Turkey is where its made. It hasn't worked as good. This has really been hard on me. I hope Mylan gets a heart and start making it again.”

Frustrated · Taken for 10 years or more June 15, 2020

For Depression: “Still calling the manufacturer to see when maprotiline will become available again! Was told May then June and now August. Not sure why it is so difficult to make. Trying my fifth antidepressant and nothing works as well with the least side effects as maprotiline.”

10 / 10
elkay January 7, 2011

Ludiomil (maprotiline) for Panic Disorder: “I have been on maprotiline for over 20 years to treat my panic disorder. It was the only medication that worked and I tried just about all of them ( tricyclic antidepressants, MAO inhibitors, Prozac, Wellbutrin). Hands down, this medication had the least side effects, and the best coverage. I have been living a full life, panic free.”

9 / 10
Ran · Taken for 10 years or more November 11, 2019

For Major Depressive Disorder: “I’m 45 years old and have been on this Rx - ludiomil then it’s generic Maprotiline since age 9. It just recently became unavailable in the US and the fears I’m having about no longer being able to be stable were debilitating until learning I can get Ludiomil from an online pharmacy in Canada. This Rx is a lifeline for me. Anyone concerned about going off it needs to contact them. I’m going to stockpile as much as I can incase it becomes no longer available via Canada so I’ll have enough to safely transition to another drug.”

10 / 10
Dottie122 February 3, 2014

Ludiomil (maprotiline) for Depression: “I had been on Ludiomil for over 30 yrs and they discontinued it. I went on the generic maprotiline and now there going to stop it to. I'm beside myself. I have about another month and I will be out. This medicine saved my life, I can't believe they could just stop making it for those of us on it. They say it is not addictive, but let me tell you I have tried several times to get off of it and I get all the same symptoms I had over 30 years ago on top of the withdrawal symptom I'm going to get. Life is about to go bad again. The doctor and I talked he says he won't mix maprotiline with any other medicine and I'll have to be off it for 2 weeks and before starting another medicine. This will put me into a severe depression. Nothing else works.”

Anonymous · Taken for 10 years or more July 23, 2019

For Depression: “maprotiline has been extremely effective for me for over 35 years. I have had difficulty getting it for the last 12 months and now just learned the name brand Ludiomil is still available through Canadian Pharmacies”

10 / 10
balticwolf · Taken for 1 to 6 months February 10, 2017

Ludiomil (maprotiline) for Depression: “I tried Ludiomil over thirty years ago when I was severely depressed. Of all the different antidepressants that had been prescribed for me (amitriptyline, doxepin nortriptyline, desipramine, trazadone, etc.) Ludiomil was definitely the most effective of the ones I tried. Unfortunately, it like Remeron (which I tried years later) raised my liver enzymes and I was told by my physician (I was seeing a psychiatrist at the time) to discontinue using it. But I was lucky: just before I was scheduled to undergo electro-shock therapy to cure my intractable depression, I learned that I was allergic to the milk protein and after removing it from my diet I never again had the deep melancholy I had experienced before.”

Souled on it · Taken for 10 years or more May 19, 2015

For Depression: “I have been taking maprotiline for over 35 years and I am still taking it (there seemed to be a shortage for a while about 2 years ago but Walgreens still carries it). I started having panic attacks with the onset of my allergy to dust mites when I was a teenager. In my 20's, I went into a deep depression and couldn't sleep for 3 months. I started taking maprotiline and 3 improvements occurred: 1) My depression subsided and then went away. 2) My panic attacks stopped. 3) The almost daily sneezing episodes associated with my allergy subsided, and now, they occur maybe twice and month. My runny sinuses also dried up considerably. I twice tried taking myself off of the medication--it didn't work. All problems returned after about 10 days.”

9 / 10
has bimor · Taken for 1 to 6 months January 21, 2015

For Panic Disorder: “Effective medication for panic disorder and for highly somatisation patients also very helpful for insomnia. I suggested maprotiline for patient with no response to SSRis or tricyclic antidepressants.”

10 / 10
Pookie December 6, 2019

For Depression: “I have been taking this drug maprotiline for depression for 30 years and I feel very safe taking it and no real side effects. Problem is it is back ordered and I had a hard time finding any of it except for Canada. The manufacturers says it will come back in February or May. I am not sure that will happen. My question did anyone transfer to a different drug and what was its name and how are they feeling. I am very upset that they will not continue to make maprotoline.”

10 / 10
Bobc · Taken for 10 years or more January 24, 2020

For Depression: “I have been using Maprotoline for many years. I’ve tried every antidepressant and it is the only one that works. I too am having trouble getting it and I’m very concerned. I’ve seen that some people are getting this from Canadian Pharmacies. Can anyone share the names of any such pharmacies? Help! ”

10 / 10
Map User February 27, 2009

For Depression: “I've been using Maprotiline for ten years. I think it's the best antidepressant out there but since it's not new it's not being prescribed.”

10 / 10
Nachobev · Taken for 6 months to 1 year July 13, 2015

Ludiomil (maprotiline) for Major Depressive Disorder: “I was pleased with the results of this medication. Eventually i was able to discontinue taking this medicine after 8 months.”

10 / 10
Pookie · Taken for 10 years or more May 12, 2020

For Depression: “Just wondering if anyone has found a place that has maprotilene. I was getting from Canada but it came from Turkey and now it cannot be mailed from there because of the virus.”

10 / 10
beckysis1 January 31, 2020

For Major Depressive Disorder: “Filed complaint with Mylan Laboratories for discontinuation of Ludiomil ( maprotiline). I was on it for 30 years, and now am in severe withdrawals. Can’t find it anywhere. Looking in Canada. ”

10 / 10
Has bn · Taken for 1 to 6 months January 13, 2016

For Panic Disorder: “Helps me to sleep better but no good for panic attacks and only side effects hypotension”

3 / 10

This information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare practitioners.