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Letrozole and Muscle Pain: What Users Say (Page 2)

Brand names: Femara

Reviews for Letrozole

Commonly mentioned side effects
  • Mic...
  • February 7, 2017

For Breast Cancer "Stage 3 breast cancer. Double mastectomy, chemo, radiation. Started letrozole about 5 months ago. Severe joint and muscle pain, especially in shoulders, arms, and hands. 20 lb weight gain. Seriously hate this medication but afraid to go off it because supposedly it reduces my recurrence rate. I'm trying acupuncture for the joint pains."

1 / 10
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31 Report
  • can...
  • Taken for 1 to 2 years
  • February 27, 2018

For Breast Cancer, Adjuvant "In 2015, I was diagnosed with stage 2A right breast cancer. I had a mastectomy and reconstruction, as well as a full hysterectomy. This is my second year on Letrozole (scheduled for 5), and my symptoms have just started. Mild headaches, back and neck pain, muscle aches, weight gain, and hair loss. The latest is nausea, which I hate! I have high blood pressure, and it has been going up alarmingly. That's really the main concern that I have since heart disease and strokes run in my family. For the first year, I had no side effects, but now it seems like every one of them is converging at the same time. I'm wondering what I'll experience next, but I've decided to remain on the medication and will try to mitigate the symptoms as best I can. I'm 48 and have had a wonderful life, but I'm living for my family, and especially my new grandchild. So, I'll suffer, but it's worth it to stick around for as long as I can."

5 / 10
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25 Report
  • Ini...
  • Taken for 2 to 5 years
  • July 24, 2021

Letrozole for Breast Cancer "Took Femara for 2 years+. Just saw my oncologist recently, and she asked about the joint pain. It has been awful, my joint and muscle pain is excruciating sometimes. I am a young 61 who felt 85. No more snow skiing. Could barely get out of bed many days. My oncologist suggested I take a week off of it, and if it improved the pain, she would prescribe Aromasin. Sure enough, pain all gone, and now I have been on Aromasin a week. Fingers crossed!"

4 / 10
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9 Report

Frequently asked questions

  • Anonymous
  • July 27, 2022

For Female Infertility "I was prescribed letrozole 5 mg x 5 days on cycle day 3-7. I began feeling ill on the 3rd day of taking the medication. I had really bad muscle/bone/joint aches, headaches, hot flashes, abdominal pains, lack of appetite, dry mouth, cough, dizziness, nausea, and fever. I called the pharmacy to ask about side effects and was told to complete the 5-day regimen since I only had 1 dose left. No sinus symptoms or sore throat, but I went to get COVID and flu tested and was negative. Blood work showed elevated liver enzymes. No signs of infection. Still having headaches and now stomatitis. Every day I am feeling a little better. I read side effects can take 7-10 days to subside. I am on day 6 and still don't feel like myself. Praying I do end up pregnant after experiencing almost every side effect possible. I did have an increase in follicle sizes from the medication."

3 / 10
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7 Report
  • Ano...
  • Taken for less than 1 month
  • November 12, 2019

For Female Infertility "I just started taking letrozole for help getting pregnant. I'm on 7.5 mg on Day 3 and 2.5 mg on Day 4. I had to decrease the dose due to the side effects. I have joint, muscle, and bone pain, tender breasts, fatigue, and headache. It's a good thing that I am not working at this time. I am wondering whether or not to continue the course."

5 / 10
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14 Report
  • Flo...
  • Taken for 1 to 6 months
  • March 20, 2016

For Breast Cancer "Stiff fingers and legs, joint pain, swollen fingers and toes, hip pain, hot flashes, night sweats, and weight gain."

6 / 10
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47 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.