Semglee User Reviews & Ratings
Semglee has an average rating of 3.7 out of 10 from a total of 13 reviews on Drugs.com. 15% of reviewers reported a positive experience, while 62% reported a negative experience.
Condition | Avg. Rating | Reviews | Compare |
---|---|---|---|
Type 2 Diabetes | 11 reviews for Type 2 Diabetes | 159 medications | |
Diabetes, Type 1 | 2 reviews for Diabetes, Type 1 | 78 medications |
Reviews for Semglee
- Anonymous
- Taken for 6 months to 1 year
- May 12, 2023
For Diabetes, Type 1 "Was switched from Lantus to Semglee. Severe rash, itching all over body. Injection sites burn with rash and sores. I hate this stuff. Take it off the shelves. Going back to Lantus. Insurance companies should be held liable for making people change to this junk."
- Meh...
- Taken for less than 1 month
- June 5, 2025
For Type 2 Diabetes "Injection site felt irritated. Blurred vision, feeling all the time dizzy and sleepy. All the time tiredness, and the worst part, I just started using it like days ago. That's not what I was expecting shifting to insulin from metformin."
Frequently asked questions
- Biosimilars vs Biologics: What are they and how do they compare?
- What biosimilars have been approved in the United States?
- How and where should I inject insulin?
- When is the best time to take Toujeo?
- Anonymous
- Taken for 1 to 6 months
- November 8, 2022
For Type 2 Diabetes "I had awful side effects from Tresiba, so my doctor prescribed Novolog. My insurance refused to cover it, so I am now on Semglee. My blood glucose level has been better, however, it feels like I am injecting alcohol every time I use it. The burn is horrible."
- JM...
- Taken for less than 1 month
- May 23, 2024
For Type 2 Diabetes "I was put on Lantus because of Prednisone. It was an easy transition from Metformin. I was switched immediately to Semglee. It works well but burns at the injection site when injected. I see others have had similar experiences. I didn't have this problem with Lantus."
- Phi...
- Taken for less than 1 month
- June 24, 2023
For Type 2 Diabetes "I am able to control my blood sugar without medication. I went into the hospital for pneumonia, and they feed you food that is NOT good for diabetics, so naturally, my blood sugar went up. They gave me insulin and long-acting insulin. OMG, I never felt so bad as I do after I take Semglee: terrible headache, palpitations, and overall weakness. I’d rather not eat sugar or carbs like I usually do. I can’t take Semglee; no thanks!"
- Jan...
- Taken for 1 to 6 months
- April 6, 2024
For Type 2 Diabetes "Semglee has lowered my blood sugar and is very effective. It has taken me a bit to figure it out. I gained weight initially on Lantus 10 years ago - then - in 2019 I had to switch to Basaglar, then Tresiba, then Levemir due to insurance changes. I did 37 units of Levemir on a calorie restriction diet with higher protein, moderate fats, and carbs. It was working and I lost about 14 pounds. Then, because of insurance, I had to switch to Semglee 3 months ago at the same 37 units as I had with Levemir. I was gaining a pound a day! It was awful. I finally brought it down to 28 units slowly - which was the exact same threshold for me gaining on Lantus! They are so similar that way. I stopped gaining and it was very effective at controlling my sugar and I slowly dropped the weight I gained in about 5 weeks. Now I am at 24 units and it is getting almost too good at controlling my sugar, and I had a whopping hypo today after forgetting to eat. I am going to take it down to 22 units and see how it goes."
More FAQ
- How long can Toujeo stay out of the refrigerator?
- What are the different types of insulin?
- Soliqua vs Lantus: What’s the difference between them?
- Can Toujeo be given twice a day?
- Anonymous
- January 25, 2021
For Type 2 Diabetes "Since taking Semglee from September 2020, I've put on 2 stone and look nine months pregnant, huge tummy and very high sugar. Would not recommend anyone to take it, awful stuff, waste of money, cheapest on the market. I can see why."
- sun...
- Taken for 1 to 6 months
- October 6, 2022
For Type 2 Diabetes "I found out Lantus wasn't covered by my insurance about June 2022, and Semglee was a replacement, although the copay assistance card made the copay $0. I finally started taking it after using up some Lantus, and after a week, I have some hives and itching. Also, I'm unusually tired when I'm not doing anything versus when I wasn't taking it. I'm going to see if I can increase my Trulicity and get off Semglee totally."
- Ras...
- Taken for 6 months to 1 year
- June 27, 2022
For Type 2 Diabetes "I’ve been using Semglee for at least 6 months now since insurance said no to Lantus! I’ve had no bad experiences with this insulin. I’ve used 3 others, and though not my preferred, it works with no ill side effects, least not for me."
- car...
- Taken for 6 months to 1 year
- March 16, 2023
For Type 2 Diabetes "I have been feeling worse since I started taking Semglee. It caused my ankles, foot, lower legs to swell, I felt dizzy and had itching."
- had...
- April 25, 2023
For Type 2 Diabetes "Semglee put me in the hospital, via an ambulance. I had flushing of my face, a rapid heartbeat, headache, nausea, blurry eyesight, felt ready to pass out, and generally feeling bad all over."
- BMD...
- Taken for 1 to 6 months
- August 20, 2022
For Type 2 Diabetes "Been using Semglee for 1 month so far. Put on 5 pounds and had 3 pens fail so far, the plunger breaks, and you can’t use the rest of the injections."
See also:
More about Semglee (insulin glargine)
- Check interactions
- Compare alternatives
- Drug images
- Latest FDA alerts (4)
- Side effects
- Dosage information
- During pregnancy
- FDA approval history
- Drug class: insulin
Patient resources
- Semglee drug information
- Semglee (Insulin glargine, recombinant Subcutaneous) (Advanced Reading)
- Semglee (Insulin glargine-yfgn, recombinant Subcutaneous) (Advanced Reading)
Other brands
Lantus, Basaglar, Toujeo, Lantus SoloStar, ... +2 more
Professional resources
Other brands
Lantus, Basaglar, Toujeo SoloStar, Rezvoglar
For Diabetes, Type 1 "My awful insurance company stopped covering Lantus on January first, with no warning to me. When I went to pick up Lantus, the pharmacist instead gave me Semglee, a totally unknown drug to me. I did not want to take Semglee. I have many food and drug allergies. I have waited a month to hear from the insurance if they will still allow me to get Lantus because of my allergic reaction concerns upon switching to Semglee. I finally ran out of Lantus today and tried Semglee. Redness and radiating soreness at the injection site, dizzy, feel faint. I took a reduced dose from my Lantus dose out of fear of a bad reaction. That was a good call. I am not taking this again. Will just use higher doses of Novolog without a supporting long-lasting insulin. Crappy insurance company changes my Lantus after 20 years of successful use. I hope they are happy with their extra money."