Leqvio for High Cholesterol User Reviews (Page 2)

• you...
• Taken for 1 to 2 years
• October 2, 2024

"No problems with the injection site, only sore for about an hour, then nothing. As for the side effects, I seem to get a cold 3-7 days after the injection. Once very severe, with coughing, but my last injection only produced a runny nose and some upper chest congestion. I have BPH, so it is hard for me to determine if some burning and slight pain is caused by the BPH or the injection. As for my LDL, it has been reduced by about 30%."

• Mik...
• Taken for 1 to 2 years
• August 11, 2024

"I'm a 77-year-old man in good health. I just had my third 6-month injection from Metro Infusion Center. I'm happy to report no lasting side effects after my last injection. Site injection pain disappeared in less than 24 hrs. So far, I'm very happy with it. All my extensive blood work results come back normal, including my blood glucose level (85)."

• pau...
• Taken for 6 months to 1 year
• June 20, 2024

"Two shots so far. Both times, worse stiff toes and ankles, low back pain, stiff neck, and shoulders. First time, these resolved in about a week. Stiff toes and ankles never resolve completely along with numbness in feet as a result of taking statins. Deemed statin intolerant, which is why trying the Leqvio shot. Odd side effect both times is eye irritation that feels like a stye coming on but never develops. Doing blood work to see how results are with two shots and low-fat lifestyle (down 25 lbs, weigh now what I did in my 20s). It better help or not sure all this is worth it! (Recommend with the caveat of the above)"

• OCD...
• Taken for 1 to 6 months
• August 8, 2025

"Overall good experience with this drug, not had any side effects, I did lose a bit of weight but that's mainly because I went on a low fat low carb diet. The only complaint I have is regarding the area where the needle and the medication go in... it's a bit painful and bruised for a couple of days. Second jab done today hope it does its job and I'll be taken off it in the near future."

• Ano...
• Taken for 1 to 6 months
• July 21, 2025

"I was previously on Repatha for a year and began unbearable side effects, so I was changed to Leqvio. About 3 weeks after my first injection, I began having migraine headaches, intense neck and lower back/muscle pain, fatigue, chest pain, and purpura on my right arm. The symptoms are beginning to lessen now that I am three months in and due for my next injection, which I will not be taking. It did keep my cholesterol level down but not as well as while taking Repatha. My triglycerides raised considerably to a high level."

• Red...
• Taken for 1 to 6 months
• July 16, 2025

"Just had my 2nd infusion. First one, no issues besides tenderness in arm of injection. 2nd one, I received 2 days after being on a cruise/flying and all kinds of coughing people. Was OK when I went in, but the next morning felt lightheaded and like I had a horrible cold. Hubs started feeling sickly also, so I am not sure if we got some germs on our travel or if the Leqvio was my culprit. Lasted around a week. Onward, I take warfarin for a mechanical heart valve. On a substantial amount (17 mgs) but normally numbers do not change much. During the period of my first infusion, I needed to start adding more warfarin to my daily dosage. After my second infusion, I realized that the dates of my adding extra started in this time period. I have raised my numbers to 20 mg a day, I was on around 17 mg prior. Correlation? Who knows but will consult with the doctor at Mayo Clinic at the end of the month. Curious if anyone else has had these issues..."

• Gui...
• Taken for less than 1 month
• October 19, 2024

"In 2022, I got my first Leqvio injection in the doctor's office. I loved the results, my HDL cholesterol went to normal for a long period of time. This is the only medicine my body tolerated without any secondary effects. I beg my doctors to please get me back on, they prescribe, but insurance declined, subject to a letter of necessity, but that fails to fulfill the purpose. The doctor's office claims they did submit insurance claims, they never got it. I still need this injection. I have conventional Medicare Part B and D."

• cla...
• Taken for 6 months to 1 year
• March 21, 2025

"I was unable to use statins because of serious, severe side effects. I have had 2 injections so far and have had zero side effects. Leqvio has lowered my cholesterol levels to normal with the 2 injections! I will be continuing with these injections as prescribed. Very happy with the results. I am 70 and a female."

• jeg...
• Taken for 6 months to 1 year
• February 22, 2025

"Hives and hand numbness approximately 2.5 weeks after the second shot -- in the arm that received the shot. Severe body aches gradually faded after the first shot in about 4 to 5 weeks. I am not far enough along from the second shot to know if/when the body aches will fade."

• rev...
• Taken for 1 to 6 months
• April 26, 2024

"The Leqvio injection was a brief stop at the cardiologist's office. Typical, brief shot in the back of the arm. Easy. They held me there for ~15 minutes to ensure no injection symptoms. The nurse administering the injection did it very well. No pain or discomfort. I don't have serum numbers yet so I am unable to speak to the effectiveness, but I wish all my meds could be this easy."

• Ano...
• Taken for 6 months to 1 year
• March 30, 2025

"My experience with Leqvio has been very good. My cholesterol went from 140 LDL to 50 LDL after the second shot. The shot was relatively painless, less than the flu shot. No side effects. I am a 61-year-old man who feels relieved not to have to take a statin every day."

• Fra...
• Taken for 6 months to 1 year
• January 28, 2025

"I am 76 years old and female and eat a heart-healthy diet. I am scheduled for a 3rd injection in March. To begin with, my cholesterol levels were not much over the suggested limits, but since I have hereditary high blood pressure and a family history of heart attacks, Leqvio was prescribed. I didn't want to take another prescription pill since I was already taking 5 (3 for high blood pressure, 1 for thyroid, and 1 for acid reflux). I preferred an injection 2 times a year. It is given in the fat of the arm, not the muscle, so uncomfortable side effects were minimal and brief. The only other possible side effect was cramping from my calf to my foot, mostly at night. This subsided after about a month. My bad cholesterol dropped significantly, and my good cholesterol remained very good. Although it does mean another trip to the doctor's office for the nurse to give the injection, it is very quick."

• drc...
• Taken for less than 1 month
• May 7, 2025

"Started first injection 2 weeks ago. A week later, very loose bowels for three days. I don't have any muscle and joint pain like the statin drugs caused. But I am very fatigued during the day, my legs are weak. Even after sleeping 8 hours. But if it lowers my LDL and I don't have to have bypass surgery again, I can live with it. I plan on starting strength training with weights to see if I can counteract the fatigue, plus B12 supplement."

• Leq...
• Taken for 1 to 6 months
• February 20, 2025

"Nothing seemed to work to lower my cholesterol to acceptable levels, but using Leqvio along with a statin and ezetimibe brought my total cholesterol to 126. I have had no side effects from Leqvio. My only criticism is the cost."

• Div...
• Taken for 1 to 6 months
• March 15, 2023

"I am having the most severe muscle pain and tight muscles I have ever had since I have been on Leqvio. Has anyone else had this?"

• Anonymous
• Taken for 1 to 6 months
• May 8, 2023

"Side effects, hives, itching, pain with urination, headaches, dizziness, blurred vision, and sweating."

• Eli...
• Taken for 6 months to 1 year
• April 3, 2024

"About a month after Leqvio shot, I get heartburn, nausea, belly cramps, fatigue. Numbers are good, but not liking the side effects. Anyone else having similar issues?"

• San...
• September 4, 2024

"Two weeks after the first injection, I developed pain in my hips, lower back, ankles, feet, hands, including toes and fingers, burning with urination, burning in my eyes, fatigue, and headaches."

• rog...
• Taken for 6 months to 1 year
• May 19, 2024

"Not sure if this is related to Leqvio or not, however, since beginning the Leqvio regimen I have experienced an increased level of muscle and joint pain and reduced mobility."

• Dav...
• Taken for 1 to 6 months
• August 6, 2023

"Leqvio works very well to lower the LDL cholesterol, but I am having substantial weakness in my legs. No other side effects. Would hope there is some way to eliminate the weakness."

• Eli...
• Taken for 1 to 2 years
• May 22, 2024

"Had high hopes, but too many gastrointestinal side effects. Also muscle pain and stiffness. Lowers cholesterol but 2 months after the shot, I still have side effects."

• L h...
• Taken for 6 months to 1 year
• May 28, 2024

"It has lowered my LDL. However, I have noticed that my skin started to wrinkle a great deal after my third shot. Has anyone else experienced this symptom? It is my only adverse reaction."

• Ano...
• Taken for 6 months to 1 year
• June 5, 2025

"My cholesterol is better, but I hurt all over! I don’t know if Leqvio is causing this, but I feel like I didn’t hurt this bad before!"

• Anonymous
• Taken for 6 months to 1 year
• May 6, 2023

"Took first dose in October 2022. Bad cholesterol was 105. Second dose in January. Bad cholesterol was 45 in February. Cardiologist was amazed!! Feel much better this summer."

• Anonymous
• Taken for 1 to 6 months
• January 13, 2025

"After my first injection, all seemed fine, but two weeks in I have arthralgias of the fingers and severe constipation, dry lips."