Leqvio for High Cholesterol, Familial Heterozygous User Reviews
Leqvio has an average rating of 7.8 out of 10 from a total of 17 reviews for the treatment of High Cholesterol, Familial Heterozygous. 65% of reviewers reported a positive experience, while 6% reported a negative experience.
Reviews for Leqvio
- Louis...
- March 9, 2023
"After 45 days of use I have developed severe muscle pain and lower body stiffness, much worse than statin pain . I do not have brain fog, muscle cramps , skin rashes or other problems I had with statin."
- youra...
- Taken for 6 months to 1 year
- August 17, 2023
"The real answer is, I don't know. I'm on my 4th injection and haven't noticed side effects. But I have numerous problems with recovery from CABG surgery that could be misunderstood and attributed to this medication. I do have severe leg and calf cramps at times, and I am starting to believe it is Leqvio. In the past, my cramps became so severe I ended up rupturing an Achilles tendon, this was while taking Repatha. I stopped Repatha and the cramps stopped. But recently while taking Leqvio, I started similar cramps, and they can be severe. Now since the med is administered every 6 months, it is hard to stop it and see viable results, no cramps. Not sure what to do at this time."
Frequently asked questions
- What is the difference between Leqvio and Repatha?
- What are PCSK9 Inhibitors and how do they work?
- Can Leqvio be taken without a statin?
- Does Leqvio cause weight gain?
- Doc
- Taken for 6 months to 1 year
- June 27, 2023
"My cholesterol numbers have dropped specifically Lp(a) has gone down significantly. I like not having to give myself an injection every 2 weeks as I did with Repatha. I have some annoying side effects, however, including a productive cough, UTI's, problems, and sometimes painful urination, and frequently I feel dizzy which is very annoying. I believe that I am losing my hair due to this drug."
- Mlh
- Taken for 1 to 6 months
- April 23, 2023
"I had my second dose of Leqvio 2 weeks ago. I know it's working because the xanthelasma in the corner of my eye totally disappeared. I came here to give it another great review but noticed the reviews about major muscle pain. I am in extreme pain but thought it was from my fibromyalgia. I am now wondering if it's from the leqvio?? I see my doctor soon and will be asking her. So far though this is the only thing that has been working for me. I had that reaction to Repatha and I hated statins."
Are you taking this medicine?
- Jfox
- Taken for 1 to 6 months
- September 19, 2023
"Don't know yet if it helped. Switched from Repatha due to cost. After the first dose, LDL was higher, but the doctor said to wait until the second dose to see. I had a bad headache, dizziness, brief shortness of breath, and exhaustion after the first dose. After the second dose, all those effects were repeated (except shortness of breath) but for a longer period, lasting over two weeks. After 6 weeks, I am still experiencing exhaustion and occasional headaches. I think I'm losing my hair and my feet itch like crazy. Is all of this related? I feel like a hypochondriac. I hope the exhaustion is not permanent. I will be going back to Repatha... I will have to find a way to pay for it."
- Sue
- Taken for 1 to 6 months
- May 17, 2023
"I have had my first and second doses of Leqvio and unfortunately, I am having a lot of muscle and joint pain - primarily in my back, neck, and shoulders. It is quite similar to the pain I was having from taking statins so not sure why that is. It has definitely improved my cholesterol numbers which is a plus."
More FAQ
- How is Leqvio injection administered?
- What is the mechanism of action for Leqvio (inclisiran)?
- Is Leqvio FDA approved as a high cholesterol treatment?
- Who is the actor in the Leqvio commercial?
- Mlh
- Taken for 6 months to 1 year
- July 12, 2023
"Well, I have commented on here before about my results with Leqvio. I have had two shots now, and my side effects have been some muscle pain, and I got a condition called LPP from the Repatha which continues. This is hair loss. I don't know if the Leqvio is continuing it, but I just got my first cholesterol blood results and I am shocked! 18 months ago, my total cholesterol was 359. Today, my total cholesterol is 212, almost normal. Even my triglycerides, which it is not supposed to help, went down from 187 to 157. My cholesterol has been high all my life... over 300, so to see it this low, I am stunned!"
- John
- Taken for 1 to 6 months
- May 6, 2023
"I am a 74 year old male.Just had second dose of Leqvio.(I had to stop Praluent after two dosages due to extreme itching). LDL has reduced by 50% after the first dosage 3 months ago. I have experienced slight muscle discomfort but nothing major Highly recommend treatment, but it is expensive."
- Its...
- Taken for 2 to 5 years
- October 14, 2023
"I am on 5th Jap and this wonder drug bring down my bad cholesterol from 181 to 92 below 100 the recommended figure to be safe from heart attack…my gd cholesterol shoot upto 60 but nt sure it’s bcoz of leqvio or my fd habit…I got zero side effects…noting but when I took repatha I felt like dying so do other satins"
- Bon
- Taken for 6 months to 1 year
- January 4, 2024
"It has tremendously lowered my LDL. Side effects known: bad joint pain in my hips and knees. Lethargy, lack of energy. Possible side effects, but need to discuss with my doctor: racing heart waking me up from a sound sleep."
- Nick
- Taken for 1 to 2 years
- March 30, 2024
"Works awesome! Knocked the LDL down to almost in range. Had to additionally take Nexletol to nail the range because I cannot take a statin... Was extremely hard to have the insurance approve both drugs."
- Stacy
- Taken for 6 months to 1 year
- March 14, 2024
"I could not take statins without side effects. Sore muscles aching joints. I was crying at night, could not sleep. After using Leqvio for 2 doses, I don't even need to take any statins. I also changed the way I eat."
- Jayne
- Taken for 1 to 6 months
- April 13, 2024
"I've just had my second injection. Cholesterol dropped, so that's a positive. I still have an injection site rash, possibly due to this last injection being very uncomfortable, unlike the first one. My IBS has been really bad this time too, but not sure if connected. Jury's still out as to whether I would have a 3rd."
- Susan...
- Taken for 1 to 6 months
- May 25, 2023
"Have had significant hair loss. Pain in legs and knee joints. Both knees have cartilage and meniscus damage, with no previous history of knee injury or knee related issues."
- Mlh
- Taken for 1 to 6 months
- March 12, 2023
"I had a terrible reaction to repatha so I requested Leqvio. I had my first dose 3 months ago and I haven't had any problems with it at all. I have my second dose scheduled in another 2 weeks."
- shellie
- Taken for 1 to 6 months
- April 12, 2024
"Have felt better, not had blood work yet to check levels."
Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.
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"Since first the injection my A1C has spiked to 12.5 and my blood glucose is dangerously high. This has necessitated the prescription of Insulin which has a range of serious side effects. While my bad cholesterol level has dropped there has been no effect on triglycerides. Good cholesterol was in the normal range prior to Leqvio and is holding. Angina chest pain and difficulty moving with overall neuralgia are other unwanted symptoms. I am due for a second injection and have reservations."