Inclisiran for High Cholesterol, Familial Heterozygous User Reviews (Page 2)

• Let...
• Taken for 6 months to 1 year
• January 30, 2025

Inclisiran "Initial lowered cholesterol, but later injections, severe rash appeared many days later, size of lemon at injection site. Very sore, red, and itchy, lasting many weeks. Antihistamines helped, as well as cold compression."

• Anonymous
• Taken for 1 to 2 years
• September 14, 2022

"After a >99% occlusion of my LAD was detected, I had a stent implanted at 43 years old. Untreated, my total cholesterol was at 360 mg/dl, with LDL 260. Atorvastatin plus Ezetimibe did not lower the numbers sufficiently. Inclisiran was prescribed by my cardiologist in 2021, and 2 weeks after the first injection, my numbers are amazing. LDL has been below 55 mg/dl ever since. No side effects except for the rather painful injection. Amazing. Will undergo coronary radiography in 2024 to assess whether the good numbers translate into disease regression. (I'm from Germany, where Inclisiran was approved in 2020.)"

• cel...
• Taken for 1 to 2 years
• January 27, 2024

"I've had 3 injections, last one early December. Straight away, it floored me: headache, blurred vision, feeling weak all the time, muscle and joint pain, can't walk far, so much pain in hips, shivers, like I had influenza all the time. Quality of life-I was an energetic person. I had this injection. On a positive side, reduced cholesterol level in half. I'm due for another injection in June 24, not having it. My life has changed so much. I'll take my chances in exchange for the quality of life to return to what it was!"

• Sta...
• Taken for 6 months to 1 year
• March 14, 2024

Inclisiran "I could not take statins without side effects. Sore muscles, aching joints. I was crying at night, could not sleep. After using Leqvio for 2 doses, I don't even need to take any statins. I also changed the way I eat."

• leq...
• Taken for 6 months to 1 year
• March 21, 2024

"LDL has lowered to the required level. But experienced elevated liver ALTs. Has anyone else observed this? Also, headaches, fatigue, and bowel movements became terrible. Taken 2 doses and won't be taking the third now."

• KMR...
• Taken for less than 1 month
• March 3, 2024

"First dose in January. Injection site was painful for a good two weeks. Glad it was in my thigh. Two weeks post shot, I have been having trouble sleeping. I feel as though I've drank ten cups of coffee and am jittery. I actually quit drinking my one cup of coffee in hopes that it would solve the problem, but it did not. I guess I am not sure if it is the shot or something else."

• Sus...
• November 24, 2024

Inclisiran "Within 45 days after my first injection of Leqvio, my lipids decreased significantly. I was pleasantly surprised and quite pleased with the results. I am currently receiving the injection every 6 months."

• Wil...
• Taken for 6 months to 1 year
• March 13, 2025

Inclisiran "The side effects listed are about right. Had some periods of dizziness too. I have had bouts of big-time fatigue, and I think that is a result of the Leqvio. The side effects are aggravating, but in general, are worth it for the results."

• Jul...
• Taken for 1 to 6 months
• January 29, 2025

"I was told it had not thrown up any side effects, but in actual fact, there are many documented. I've had a lot of musculoskeletal problems, aches, pain, unable to function well in the day, confusion, sleeping like a log, can't get up in the morning. I'm going to have one more injection. If the same happens again, I'm stopping it."

• Sus...
• Taken for 1 to 6 months
• May 25, 2023

Inclisiran "Have had significant hair loss. Pain in legs and knee joints. Both knees have cartilage and meniscus damage, with no previous history of knee injury or knee-related issues."

• Mlh...
• Taken for 1 to 6 months
• March 12, 2023

Inclisiran "I had a terrible reaction to Repatha, so I requested Leqvio. I had my first dose 3 months ago, and I haven't had any problems with it at all. I have my second dose scheduled in another 2 weeks."

• Fre...
• Taken for 2 to 5 years
• June 29, 2024

Inclisiran "Have just received my 4th injection. Further to my May '23 post. Cholesterol has remained low, slight muscle pain continues, believe it has contributed to some hair loss. Feel overall more energetic."

• Ano...
• Taken for 6 months to 1 year
• May 30, 2025

"Itchy erythema: 10 cm in diameter for over 10 days and sore joints."

• Ifr...
• Taken for 1 to 2 years
• February 23, 2025

Inclisiran "Reduced LDL, now listed as too low. UTIs, leg pain, hand nodules. Have to wait out the 6-month dosage to eliminate it."

• she...
• Taken for 1 to 6 months
• April 12, 2024

Inclisiran "Have felt better, not had blood work yet to check levels."