Hydroxyprogesterone and Nausea: What Users Say

• Mom...
• Taken for less than 1 month
• March 18, 2017

For Premature Labor "My oldest was born at 24 weeks due to unexplained preterm labor. We spent 112 days in the NICU with him, and he is wonderfully thriving now. When discussing a sibling, we reviewed all the risks with our doctor. She recommended Makena. We were lucky to have my insurance approve the cost without a fight. Guess they weighed the cost of a lengthy NICU stay against the cost of the shots. We started Makena at 16 weeks and continued them to 36 weeks. The shots themselves stung a bit but were easily managed. My only real side effects were headaches the day of, a little nausea, and some back pain the day after. My pregnancy went to 39 weeks, and I was induced due to my advanced maternal age."

• Ash...
• Taken for less than 1 month
• July 31, 2019

For Premature Labor "Went in yesterday and received my first Makena shot at 19 weeks. It was not painful in my hip and hasn’t even itched, however, just minutes after injection, I got extremely hot, dizzy, shaky, nauseous, and nearly passed out! So either my blood sugar coincidentally dropped immediately after I received the injection or it was a strange side effect."

• May...
• Taken for 1 to 6 months
• July 3, 2017

For Premature Labor "Had my first at 32 weeks. She was in the NICU for almost 2 months. Ultimately, we decided to try again. My doctor started me on the Makena shots at 16 weeks. The shot itself didn't hurt going in because I would make the nurse pinch my arm. It burned going in a little. In the beginning, I had a site reaction of swelling, warmth, itchiness, and sometimes soreness like I was punched in the arm. Around the halfway point, that all went away. I did experience some dizziness, nausea, and fatigue, but now that I'm down to my last 3 shots, no side effects. Also, I recommend alternating arms. It hurts less than hips. Makena care connection is available. If you can't afford."

• Lou...
• Taken for 1 to 6 months
• January 20, 2019

For Premature Labor "I got the IM injections with my previous pregnancy. I didn’t recall any awful side effects besides some hives that went away with hydrocortisone. I have a drug sensitivity to the progesterone, but unfortunately, there isn’t an alternative, so I thought I'd try a different form. So this pregnancy, I got the Makena auto-injection SQ into the arms. It is extremely painful and causes nausea after the shot, and I have a huge lump. No pressure can be put on that arm or it hurts an incredible amount. I still have a few left I’ll use, but once I’m done, I’ll go back to the hip IM injections. They were not anywhere near as painful."

• Car...
• September 26, 2017

For Premature Labor "I started these shots 16 weeks ago. I'm now 35 weeks. I've had many side effects: retaining fluid twice, headaches all the time, nausea, and I had high blood pressure once. I think I would have rather tried to do this pregnancy on my own. Yes, I've had early-term pregnancy, but all pregnancies are different, and I think I would have been better off without the Makena this time."

• Nik...
• September 14, 2017

For Premature Labor "Today is my first day taking the shot. I feel nauseous, weak, and the place where they gave me the shot hurts. I took it at 9 this morning, and it's already 4 pm. Is it normal to feel depressed or cry for no reason during pregnancy? I had a baby 4 years ago who passed away due to a cervix being thin. I had her at 20 weeks, and now I'm pregnant with my second child, and I'm 16 weeks. I hope everything goes well and I stop feeling like this."