Fulvestrant User Reviews & Ratings (Page 2)

• Abi...
• Taken for 1 to 6 months
• September 14, 2017

Fulvestrant for Breast Cancer, Metastatic "Horrible, painful injections, my hips would swell out like a lumpy wing. Was on it for 3 months, and it was like miracle grow for my MBC, my liver mets flourished into a garden of tumors. Aromasin for 9 months started the two small liver lesions to multiply like crazy, and the Faslodex was worse. All sizes of tumors, the largest being 12 cm. I was on the cusp of liver failure. Also caused sciatica in my left side and have had that for a year and will never go away. New oncologist put me on Taxol for 7 months. The first 5 months liver enzymes were dropping, tumors shrinking, and the last 2 months Taxol stopped working. Everything reversed. Tried CMF and Xeloda, side effects were severe, I refused to do any more treatments. Abraxane now, bad side effects."

• Ano...
• Taken for 1 to 2 years
• November 21, 2020

For Breast Cancer, Metastatic "Warning: Be very careful before agreeing to treatment with fulvestrant. A study confirmed that, after breast cancer cells become resistant to fulvestrant, an aggressive phenotype frequently develops, thus causing significant migration and invasion. The study found that this occurs with breast cancer cell lines MCF7 and T47D. After about 12 months of treatment, skin lesions started forming on my breast. Over about 10 weeks to date, the lesions continue to migrate and now cover about 75% of my breast. Also, additional small lumps have appeared elsewhere below my armpit and in the center of my abdomen. Similar to another person’s post on this site, fulvestrant was “like miracle grow” for my cancer. My cancer now is more aggressive than ever since my initial diagnosis, prior to this treatment. Also, what is additionally disturbing is that the risk of this outcome is not indicated in any of the prescribing/patient information for the brand or the generic versions."

• Anonymous
• Taken for 5 to 10 years
• September 4, 2021

For Breast Cancer, Metastatic "I am 79 years old and have battled breast cancer since 1999. During that time, I had radiation and took tamoxifen. After 10 years, my cancer came back. I then had a mastectomy. Two years later, my cancer metastasized to my spine. Thank God for fulvestrant! I have now been on fulvestrant for 7 1/2 years. I have had constant sweats (I have a mini fan I always have with me), constantly tired, no energy, constipation. At this time, my blood work is fine, and my cancer is dormant. The side effects are not fun at all, but I definitely can handle it with a smile on my face because I am alive! Thanks to all who have shared their experiences."

• Bar...
• Taken for 1 to 6 months
• May 10, 2024

Fulvestrant for Breast Cancer, Metastatic "Went stage 4 with mets to bones and one lung- started Fulvestrant 3 months ago. I can cope with all the minor side effects- but what has been a big problem is that I seem to have a permanent cold/flu/COVID. It's making me miserable, and it must be related to lowered immunity? No one else has mentioned it- so looking to see if it’s a typical problem? I'm a (previously) fit, active 51-year-old mum of 2 school-age kids, and a busy business. Mets are stable from latest PET scan."

• wil...
• Taken for 5 to 10 years
• June 17, 2022

Fulvestrant for Breast Cancer, Metastatic "I have been taking Faslodex, Zoladex, and Ibrance for 6 years. I went off of Zoladex 6 months ago! I have been tumor-free for 4.5 years. I had stage 4 cancer with all mets in my liver. They are all gone now! I also live a very holistic lifestyle and do so many things to support my system while on these pharmaceuticals. I had very little side effects, I believe because of the other modalities I incorporate into my healing protocol. In the first few months, I had mouth sores. I had a week or two of hot flashes and insomnia. Then I had no side effects. I did get some irritation and electric feels in the Faslodex injection site. After playing with injection placement, it went away. Now it is back. I am having hip pain and a feeling of burning on my skin near the injection site. I heard they are only supposed to put up to 2.5 cc's of medicine into a muscle. These shots are 5 cc's, which is concerning to me. I am looking to stop this medication soon. I feel I don't need it anymore."

• Poe...
• Taken for 1 to 6 months
• December 16, 2021

For Breast Cancer, Metastatic "I am having a negative experience and discontinuing care. After the 2nd injection, liver enzymes spiked. I'm badly jaundiced, nauseous, and itchy. I cannot properly digest food, and it's difficult and painful to void my bowels, walk, and drive. At only 39, I still value quality of life over quantity, and this drug provides an unacceptable quality of life. I am working with an integrative clinic to flush it from my system because it's dreadfully long-lasting. My advice is not to use this, especially if you have a history of liver disorder or disease."

• Old...
• Taken for 1 to 6 months
• April 20, 2020

Fulvestrant for Breast Cancer "It didn't work for me. I was on it about 3 months, and I was in so much pain that it was hard. The pain was in my joints and bony surfaces. The doctor did put me on Celebrex, and that made the pain go away. I can't give it a good review because it didn't work for me."

• Anonymous
• Taken for less than 1 month
• December 16, 2022

Fulvestrant for Breast Cancer, Metastatic "I was told in 2008 when (not IF) my cancer returned I would be out on tamoxifen. For the past 2/3 years, Dr. finally realized I had bone cancer, lung cancer, and inoperable kidney cancer stemming from breast cancer. I was on Aromasin, not tamoxifen. Dr. prescribed a new manageable plan - Xegva, Faslodex & Ibrance. After Xegva, my body felt like hot irons pressing against me. I went to the doctor's office the next day for the Faslodex feeling very ill and burnt on the inside. Told that was a soon-to-fade side effect. The Faslodex injections put me in a near state of paralysis… excruciating pain… beyond decency - that has lasted for 6 weeks. Ibrance lowered blood count. This was the worst pain I have ever had. Because I can’t endure the injections, the Dr. will no longer treat me. I am begging for palliative or hospice care. I was told they only treat as prescribed. No injections! No medical care/ no referral to another Dr. Hoping for hospice to ease my pain from this treatment and a peaceful end."

• Bre...
• Taken for 1 to 6 months
• September 20, 2022

For Breast Cancer, Metastatic "I was diagnosed with Stage 4 breast cancer with mets to the lung (8 mm nodule) in May 2022, which has shrunk since beginning Ibrance with exemestane in August 2022. After diagnostic molecular pathology of the cancer cells, it was discovered that I have an ESR1 mutation that indicates the ineffectiveness of the aromatase inhibitor, exemestane. I had my second injection of fulvestrant yesterday, two weeks after the first. I haven't had many side effects that lasted more than a week. My urine smells horrible, and I feel as though it seeps through the skin. I had joint pain for two days after the last injection and the day of this time. Additionally, I experienced a week of brain fog after the first injection, which I am not experiencing this time. Thankfully, other than the aforementioned side effects, I am not feeling anything, and I pray that it remains this way. I have a PET scan scheduled in a month, and I am eager to see how things are going internally because, externally, I feel great."

• Lov...
• Taken for 5 to 10 years
• November 27, 2022

Fulvestrant for Breast Cancer, Metastatic "I was diagnosed with Mets to the bone 5 years ago. I have been on Ibrance (oral), Xgeva, and Faslodex injections, both given 1x monthly. My Mets from breast cancer are mostly in my pelvic/seat bone region, but I also have them on my skull, arm, and leg bones. I had a pelvic fracture due to weakness in bone density, which was very painful. This led me to an orthopedic surgeon and the discovery that I needed a hip replacement. I am seventy, and so I would like to suggest to people with hip pain to investigate other causes with a specialist. I was using a cane and in a great deal of pain. Since having a hip replacement, I hardly have any pain at all, and I can walk without a cane and ride my horse. My only issue is muscle cramps in my feet, legs, and occasionally pectoral (chest) muscles. I would like to know how to avoid these painful nighttime terrors and what causes them. Ibrance is expensive at nearly 800.00/mo, even with good insurance. I have lived 11 years since the original breast cancer diagnosis and lumpectomy."

• Ter...
• Taken for less than 1 month
• June 6, 2023

For Breast Cancer, Metastatic "I received 2 injections 7 days ago. Four days after, my blood pressure went down to 100/67. I had to stay in bed that day. I had a strange creepy feeling in my brain with the feeling of a lump inside my head. That went away. I have had tingling and muscle weakness in my hands and forearms. I have severe dizziness upon sitting up or closing my eyes in the shower. My voice is hoarse and faint. My doctor thinks I am making this up."

• Kat...
• Taken for 1 to 6 months
• June 9, 2023

Fulvestrant for Breast Cancer, Metastatic "I am in my third month of Ibrance and Faslodex. The shots are very painful, and they make me feel horrible the day of the shot. My urine is also embarrassingly smelly. Using a heating pad is somewhat helpful. Is there not a way to make these shots less painful? My side effects include constipation, continual pain at the injection site, lower back discomfort, and headaches. My numbers did go down after two months. Not sure how long I can stay on this drug."

• Bet...
• Taken for 1 to 2 years
• April 13, 2024

Fulvestrant for Breast Cancer, Metastatic "I have been receiving injections of Faslodex for one year now. I have done much research on Faslodex and found that it has given me peripheral neuropathy in my foot and thigh. Not everyone will experience this condition, but I do still take the injection hoping for the best. I also have some arm pains and dry mouth. Every third week, I take Xgeva for my bones and will continue treatment until some other treatment comes my way."

• Jul...
• Taken for 2 to 5 years
• March 27, 2024

For Breast Cancer, Metastatic "I have been on Faslodex injections since April of 2022. About 6 months after the initial injections, I had my first side effect. It was a severe burning sensation in my lungs and throat, which caused coughing. This still happens but is random. In total, it’s happened about 6 or 7 times over the past 2 years."

• 708...
• Taken for 6 months to 1 year
• February 2, 2023

For Breast Cancer, Metastatic "Started fulvestrant 2/2022. Was fine until 4/2022. From 4/2022-10/2022, I was severely fatigued. In April, I spent 11 days in bed, feeling overall like poop. I had my labs done, which showed nothing. Covid and flu tested negative. Dr. says not fulvestrant. After the 11 days, I was slightly better. Still sleeping 11-12 hours and on the couch, and when I did get up, I was not hungry at all. Forced myself to eat. A few times, I was so weak I went to the oncology office in a wheelchair and lay down once inside. The only way I felt halfway decent was laying down. My BP was fine. Still no explanation. I skipped my Oct shot and began to feel better, slow but improving. Resumed shot in Nov 2022. Fatigued but not anywhere close to that level. After the Dec 2022 injection, my neuropathy started returning in my feet. I had it from chemo back in 2010. It went away 2011/12. It’s mostly at night after I go to bed and my feet get hot. The balls of my feet up to where my toes begin itch so bad. Nothing helps. I took Jan 2023 off. Neuropathy continues. Will be stopping."

• Anonymous
• Taken for 6 months to 1 year
• July 12, 2024

Fulvestrant for Breast Cancer, Metastatic "On Faslodex for a year. Ok so far, just some tiredness and loss of appetite, and some dizziness if I don't keep moving. Scans stable."

• pep...
• Taken for 5 to 10 years
• July 8, 2023

For Breast Cancer, Metastatic "Love it. Working 6 years so far. Far rather get the shots monthly than take pills daily. The lack of estrogen causes effects that are necessary no matter what drug is used. Not toxic like chemo."

• Anonymous
• October 10, 2020

Fulvestrant for Breast Cancer, Metastatic "It makes my urine and feces smell for a week. Probably goes through my pores. If you stand close to me, you can smell it."

• Ion...
• Taken for 5 to 10 years
• November 10, 2023

Fulvestrant for Breast Cancer, Metastatic "Tolerable - few side effects. Prefer it to any other med. Dosage 500ml (2)"

• Che...
• Taken for 6 months to 1 year
• January 19, 2021

Fulvestrant for Breast Cancer "Experience tremendous hair loss."

• Car...
• Taken for 1 to 6 months
• November 3, 2023

For Breast Cancer, Metastatic "So far, I have had no side effects with this medication. I have a great nurse who knows how to give my injections without pain."

• Mad...
• March 26, 2023

Fulvestrant for Breast Cancer, Metastatic "Currently, I am feeling pretty bad, and many of my pains appear to be due to Fulvestrant. Don't feel like doing anything."

• Ano...
• Taken for less than 1 month
• July 12, 2021

For Breast Cancer, Metastatic "I have had 2 injections so far-two weeks apart. After the injections, the skin of my buttocks is terribly itchy at the injection site. The last time, the itchiness lasted for two weeks."

• Anonymous
• Taken for 1 to 6 months
• June 14, 2023

For Breast Cancer, Metastatic "So far, this is working with mild side effects. Have been on this for 5 months. Injections are uncomfortable but tolerable."

• Bal...
• Taken for 6 months to 1 year
• March 4, 2023

For Breast Cancer, Metastatic "Regression of metastatic lesions was achieved within 3 months. But side effects I have had include pruritus, hives, loss of eyebrows, constipation, and tiredness."