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Loestrin Fe 1/20 and Depression: What Users Say

Depression: mentioned by 6 users (18.8%)

Based on user experiences from 32 Loestrin Fe 1/20 reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

acne 31.3%
anxiety 18.8%
bleeding 18.8%
depression 18.8%
mood swings 18.8%
weight gain 18.8%
cramps 12.5%
headaches 12.5%
nausea 12.5%
pain 9.4%

Reviews for Loestrin Fe 1/20

Commonly mentioned side effects
  • Jen...
  • Taken for 2 to 5 years
  • July 28, 2020

For Birth Control "Loestrin Fe 1/20 is the best birth control pill I’ve tried. I was able to skip my periods (not take the placebo pills), and that made me not have any more PMS headaches. No depression or irritable moods like I had on Ortho Tri-Cyclen. No nausea like some other pills gave me. Didn’t really change my skin or sex drive at all. I felt like myself on this pill. I did develop high blood pressure after 3 years on it when I went through a time of stress. Not sure if due to the pill, but get regular blood pressure checks if you take any birth control pills, as it can be a side effect."

9 / 10
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7 Report
  • Kpa...
  • Taken for less than 1 month
  • August 17, 2019

For Birth Control "I only took this birth control pill for 3 days and had to stop right away, I started to experience bad anxiety and depression, and my doctor advised me to stop taking them. I am also on Wellbutrin for depression and not sure if they interact, but I highly recommend to not take this if you have anxiety and depression and take Wellbutrin as well. I cried nonstop and never felt so sad in my life."

2 / 10
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6 Report
  • 28a...
  • Taken for 1 to 6 months
  • December 18, 2016

For Birth Control "Weight gain, severe depression during PMS, and intense itching. I was on Loestrin previously, and it was great for 2 months. I had no acne, my periods were better. As of the third month, I was itching uncontrollably and was told it was dry skin, but the itching coincided with the time I took the pill. I went off the pill for a year, then my doctor put me on LoLoestrin, trying to reduce the hormone. I'm not sure if weight gain was connected to that. I was having 2 periods a month. After 8 months of that, my doctor put me back on Loestrin. I hoped it was a bad reaction to one pack before. I had debilitating depression at least one day mid-month and one during PMS. During the second month, the itching came back. I always itched 20 minutes after."

2 / 10
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4 Report
  • Bri...
  • January 28, 2021

"This is the first birth control I have been on that has made me break out. I have always had very clear skin. I was very lucky and blessed with the skin I have! My entire life, I never had breakouts, never, ever broken out on my face, and absolutely NEVER broke out on my back, neck, and chest. Yet since I started taking this Loestrin Fe 1/20 birth control, I am breaking out everywhere!!! And it’s making me so depressed, it is also messing with me mentally. I barely get my period, which is extremely bad, as I feel you need to have your full cycle every month for many reasons. I used to have a heavy one for about 5 days, and it would actually make me feel better after, now I literally spot for a day and that’s it. I also now have the worst cramps. I need to get off of this one, but I’m scared to try another one because I don’t want to gain weight, that’s the main reason I went on this birth control, but it’s not worth it with how badly I’m breaking out. I know everyone is different, but I do NOT recommend this bc."

3 / 10
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1 Report
  • Kel...
  • Taken for 1 to 6 months
  • March 20, 2018

For Birth Control "I have been taking Loestrin Fe 1/20 for almost 4 months now. Let's just say I'm going to ask for a different pill at my doctor's appointment tomorrow. This pill has caused severe tenderness in my breasts 24/7, sometimes I have what feels like heart palpitations and shortness of breath. I hardly have a period anymore, and worst of all, I cry ALL the time. I have never been an emotional person, but now all I want to do is cry about everything. I am also on Wellbutrin for anger, anxiety, and depression. I am wondering if these pills don't agree with each other. Either way, my anxiety and depression have been so much worse since starting this birth control."

2 / 10
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1 Report
  • 199...
  • Taken for 6 months to 1 year
  • October 29, 2019

For Birth Control "I was on this birth control pill in 1999 when I was 18. I took it for 6 months before I decided to stop using it. I did not have any problems with acne or cramps during use, but a serious increase in both directly after stopping. The problem for me was extreme nausea, depression, weight gain, mid-cycle bleeding, and dryness. I now realize that taking hormonal birth control, especially before having children, causes many bad side effects long-term. I would not recommend any hormonal birth control pills for anyone and wish I had never taken any."

3 / 10
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2 Report

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