Midrin User Reviews & Ratings (Page 3)
Midrin has an average rating of 9.0 out of 10 from a total of 81 reviews on Drugs.com. 85% of reviewers reported a positive experience, while 4% reported a negative experience.
Reviews for Midrin
- Tri...
- Taken for 1 to 2 years
- March 23, 2015
For Headache "This was the first medication I received for my migraines, and it worked for 90% of my migraines. However, the side effects left me dizzy, disoriented, drowsy, and just generally intoxicated and unable to perform normal work. I switched to Fioricet, and it's been a much better experience since."
- hop...
- Taken for 5 to 10 years
- September 21, 2022
For Headache "I've had a really great experience with Midrin. I spoke with my neurologist, and she suggested a compounding pharmacy. I now pick up the generic Midrin from the compounding pharmacy and have been since 2017. Check to see if you can do this!"
- Lad...
- Taken for 10 years or more
- August 16, 2018
For Headache "Midrin is the only medication that I have had success with to combat a migraine. I could take it at the onset of a migraine to stop the pain dead in its tracks. I'm currently taking Sumatriptan (generic Imitrex), which makes me sleepy enough to sleep through the pain but doesn't always elevate the pain. I've been researching Midrin today to learn whether or not it will ever be available again for migraines, but I'm not having much luck. Posting here to see if anyone knows the status and to ask others what meds they used if Imitrex didn't work for them."
- Anonymous
- September 24, 2010
For Headache "I take this for migraines. It is amazing, it usually stops my migraine within a half hour. I usually take 3 Midrin, Excedrin Migraine, and 2 aspirin. I take it during aura, usually, I have visual disturbances and numbness that travels around my body (along with some other weird, crazy stuff). I've also tried Propranolol as a preventative, but it causes chest pain and a very slow heart rate, so I'm trying Topamax. I still get 3-5 migraines a month, hormone-related. I have the Mirena IUD, I would get the Paragard, which has no hormones, but I'm allergic to metal, go figure!"
- cyn...
- Taken for 5 to 10 years
- June 2, 2022
For Headache "Midrin was the best thing ever for my migraines. They worked fast and very well. I don't know why they were discontinued. I've had migraines for 42 years, and they were the only one that worked perfectly."
- Anonymous
- July 29, 2010
For Headache "Midrin is lovely for my migraines. I was taking 800 mg of ibuprofen a day for them, and now I only have to take one Midrin for a headache to completely go away. There was slight nausea and a change of appetite, but that's to be expected."
- Anonymous
- October 26, 2009
For Headache "Five doses at best only eased migraine slightly - and at the cost of increased nausea and increased duration of migraine. Then there's the rebound headaches that last for days. Not worth it for me. Glad it works for others, though. Maxalt works, but is terribly expensive and very limited, which means it cannot be used as often as indicated."
- Anonymous
- October 15, 2010
For Headache "Been taking Midrin for 6 years. Migraines are getting worse with age. Auras, numbness in arms, cluster headaches. Can't take Motrin anymore, doctor says I've taken too much. Midrin makes me feel like I've taken a muscle relaxer after I wake up the next day. So, the day after I take this, I feel like a zombie. Still looking for something better!"
- Ano...
- April 15, 2025
For Headache "I've had migraines for over 30 years. My neurologist prescribed Fiorinal for my migraines because they caused stroke-like symptoms. I now take Fioricet because Fiorinal has aspirin, and I cannot take aspirin, due to the fact I'm on Eliquis. If you cannot find Midrin, ask your doctor for Fioricet or Fiorinal for your migraines. Some doctors believe Fioricet doesn't take care of migraines, but it does for me. Fioricet has acetaminophen. Fiorinal has aspirin."
- lit...
- September 22, 2009
For Headache "This medicine is really good, though sometimes I need to take up to 5 of them for really persistent migraines. It is very affordable, but sometimes I feel I need something other than the Elavil to really help."
- Scu...
- Taken for 10 years or more
- August 13, 2019
For Headache "Been using Midrin for headaches for over 30 years with no side effects. It works in 30 minutes to stop my aura and headache. Please bring it back so I don't have to risk suffering again."
- Anonymous
- February 21, 2019
For Headache "Miss Midrin was the only thing that helped my migraines/headaches. I've held on to a few since May 2018, but I haven't found anything equal to it."
- The...
- Taken for 1 to 6 months
- August 26, 2016
For Headache "Midrin knocks out my headache within minutes. I don't know how, but it works."
- Ned...
- January 17, 2018
For Headache "Midrin is the only medication that has worked for my migraines."
- Anonymous
- March 7, 2008
For Headache "This is about the only drug that helps my migraine, if I take it soon enough."
- Anonymous
- March 23, 2011
For Headache "I have taken Midrin for 18 years, and now I find out they took it off the market because people were abusing it. It is the only thing I have taken that has worked."
- Dan...
- Taken for 10 years or more
- December 20, 2019
For Headache "The manufacturers aren't making enough money on the old migraine meds (which Midrin is the only one that ever helped me), so they want to force everyone to pay for the newer ones."
- Anonymous
- June 26, 2011
For Headache "Midrin should be put back on the market. It was the only medicine that helped my migraines."
- Anonymous
- April 9, 2009
For Headache "Works great for my migraines when taken at the first sign of a migraine. Fast and extremely effective!"
- Anonymous
- July 20, 2008
For Headache "Midrin is the best thing I have found to help my headache, but sometimes I have to take up to five pills to feel relief."
- Anonymous
- September 29, 2008
For Headache "Midrin works much faster. I can't go without it."
- Mrs...
- May 28, 2011
For Headache "Suffering a migraine right now without Midrin, as it is no longer available."
- Anonymous
- March 18, 2008
For Headache "Midrin works very well at getting rid of my headache, but I get rebound headaches that are ten times worse."
- Anonymous
- March 11, 2012
For Headache "Sometimes it worked and sometimes not, but the best thing I've had yet and nothing has duplicated its effects yet."
See also:
More about Midrin (acetaminophen / dichloralphenazone / isometheptene mucate)
- Check interactions
- Compare alternatives
- Reviews (81)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Drug class: antimigraine agents
For Headache "I've suffered from headaches since elementary school. Somewhat pinpointed it to sinus/allergies about 15 years ago since a combination of Sudafed and ibuprofen was pretty effective. Take allergy shots, Allegra, Nasonex, and still get the headaches unless Sudafed and ibuprofen are taken. My allergist sent me to a neurologist and prescribed Midrin. So far, I like it. Took 2 at the onset of a headache as prescribed, and it worked within 45 minutes. Felt a little weird from it. So now I just take one, and it works really well all day, if not longer. It actually seems to help my eyesight a little and my focus. I was also prescribed a sleep aid, but haven't taken any since I really don't have trouble sleeping."