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Myosure Tissue Removal System


The MyoSure® tissue removal system (MTRS)

is a medical device used to remove uterine fibroids and polyps. This can help reduce heavy bleeding from your vagina. You may still be able to have normal monthly periods and become pregnant after this procedure.

Female Reproductive System

How to prepare for your procedure:

  • This procedure is usually done at a healthcare provider's office, or at an outpatient facility. Your healthcare provider will talk to you about how to prepare. You may need to stop taking blood thinners or aspirin several days before your procedure. This will help decrease your risk for bleeding. Arrange for someone to drive you home after your procedure.
  • Your provider will tell you what medicines to take or not take on the day of your procedure. You may be given an antibiotic to prevent infection. Tell healthcare providers if you have ever had an allergic reaction to an antibiotic. You may be told not to eat or drink anything after midnight on the day of your procedure.

What will happen during your procedure:

  • Local anesthesia is usually used for this procedure. You may feel pressure or pushing with this medicine, but you should not feel pain.
  • Your healthcare provider will gently insert a device into your vagina. The device opens the walls of your vagina so your healthcare provider can see your cervix. Tools or medicine will be used to open your cervix. He or she will guide a camera through your cervix and into your uterus. The camera will allow your provider to see inside your uterus to find the fibroid or polyp.
  • Your provider will next guide a wand through your vagina and into your uterus. One side of the wand is made to cut the fibroid or polyp into pieces. Suction is used to pull the small pieces into the wand to remove them from your uterus. When all the pieces have been removed, the wand will be removed.

What to expect after your procedure:

You may have some mild cramping after the procedure. This should go away soon. Your healthcare provider may tell you to take acetaminophen or an NSAID pain medicine. You should be able to go home the same day. Plan to rest when you get home. You can return to your regular activities within 2 days or as directed.

Risks of the MTRS:

Even after treatment, new fibroids may grow and need to be removed. During this procedure, your uterus may be torn, or your cervix may be damaged. You may have fluid overload. This means your body may absorb too much fluid produced during the procedure. Your healthcare provider will have to stop if this happens, and you will need another procedure to finish the tissue removal. You may bleed more than expected. This can become life-threatening.

Seek care immediately if:

  • You have heavy bleeding from your vagina that soaks more than 1 sanitary pad every hour.
  • You have abdominal cramps for more than 2 days.

Contact your healthcare provider if:

  • You have shortness of breath or feel dizzy.
  • You have nausea or are vomiting.
  • You have a fever higher than 100.4°F (38°C).
  • You have a green or foul-smelling vaginal discharge.
  • You do not get your monthly period.
  • You have trouble urinating or having a bowel movement.
  • You have questions or concerns about your condition or care.


You may need any of the following:

  • NSAIDs , such as ibuprofen, help decrease swelling, pain, and fever. NSAIDs can cause stomach bleeding or kidney problems in certain people. If you take blood thinner medicine, always ask your healthcare provider if NSAIDs are safe for you. Always read the medicine label and follow directions.
  • Acetaminophen decreases pain and fever. It is available without a doctor's order. Ask how much to take and how often to take it. Follow directions. Read the labels of all other medicines you are using to see if they also contain acetaminophen, or ask your doctor or pharmacist. Acetaminophen can cause liver damage if not taken correctly. Do not use more than 4 grams (4,000 milligrams) total of acetaminophen in one day.
  • Take your medicine as directed. Contact your healthcare provider if you think your medicine is not helping or if you have side effects. Tell him or her if you are allergic to any medicine. Keep a list of the medicines, vitamins, and herbs you take. Include the amounts, and when and why you take them. Bring the list or the pill bottles to follow-up visits. Carry your medicine list with you in case of an emergency.

Follow all instructions on when to return to your regular activities:

Your healthcare provider will tell you when it is safe to have sex, soak in a bath or hot tub, and use tampons again. It is important to follow all of these instructions to prevent an infection.


  • Rest as needed when you get home. You may have mild cramps or feel tired.
  • Apply heat to your abdomen to relieve cramps. Use a heating pad on a low setting, or a water bottle with warm water. Wrap the pad or bottle with a towel and place it on your abdomen for 20 minutes every hour, or as directed.
  • Keep a record of your monthly periods. Record the day your period started and stopped each month. Also record if you had a lighter flow than before the procedure. The first few months might vary. It may take 3 months for your period to return to normal. Bring your record with you to follow-up visits with your healthcare provider.

Follow up with your healthcare provider as directed:

Write down your questions so you remember to ask them during your visits.

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The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.