Generic Name: Abemaciclib (a bem a SYE klib)
Brand Name: Verzenio
Medically reviewed by Drugs.com. Last updated on Jun 25, 2020.
Uses of Verzenio:
- It is used to treat breast cancer.
What do I need to tell my doctor BEFORE I take Verzenio?
- If you are allergic to Verzenio (abemaciclib); any part of Verzenio (abemaciclib); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
- If you are taking any of these drugs: Carbamazepine, ketoconazole, phenobarbital or another drug like it, rifampin, ritonavir, or St. John's wort.
- If you are breast-feeding. Do not breast-feed while you take Verzenio (abemaciclib) and for 3 weeks after your last dose.
This is not a list of all drugs or health problems that interact with Verzenio (abemaciclib).
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Verzenio (abemaciclib) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Verzenio?
- Tell all of your health care providers that you take Verzenio (abemaciclib). This includes your doctors, nurses, pharmacists, and dentists.
- It is common to have diarrhea when taking Verzenio (abemaciclib). Sometimes, diarrhea has been very bad and may cause dehydration or an infection. Most of the time, diarrhea happened during the first month of treatment. If you get diarrhea, follow what your doctor told you to do. If you are not sure what to do if you get diarrhea, talk with your doctor.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- You may have more of a chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu. Some infections have been very bad and even deadly.
- Talk with your doctor before getting any vaccines. Use of some vaccines with Verzenio (abemaciclib) may either raise the chance of an infection or make the vaccine not work as well.
- You may bleed more easily. Be careful and avoid injury. Use a soft toothbrush and an electric razor.
- Blood clots have happened with Verzenio (abemaciclib). Sometimes, these blood clots have been deadly. Talk with the doctor.
- Avoid grapefruit and grapefruit juice.
- This medicine may be used with other drugs to treat your health condition. If you are also taking other drugs, talk with your doctor about the risks and side effects that may happen.
- This medicine may affect being able to father a child. Talk with the doctor.
- This medicine may cause harm to an unborn baby. A pregnancy test will be done before you start Verzenio (abemaciclib) to show that you are NOT pregnant.
- Women must use birth control while taking Verzenio (abemaciclib) and for some time after the last dose. Ask your doctor how long to use birth control. If you get pregnant, call your doctor right away.
How is this medicine (Verzenio) best taken?
Use Verzenio (abemaciclib) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Take with or without food.
- Swallow whole. Do not chew, break, or crush.
- Do not take chipped or broken tablets.
- Take Verzenio (abemaciclib) at the same time of day.
- Keep taking Verzenio (abemaciclib) as you have been told by your doctor or other health care provider, even if you feel well.
- Drink lots of noncaffeine liquids every day unless told to drink less liquid by your doctor.
- If you throw up after taking a dose, do not repeat the dose. Take your next dose at your normal time.
What do I do if I miss a dose?
- Skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
- Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- Signs of fluid and electrolyte problems like mood changes, confusion, muscle pain or weakness, a heartbeat that does not feel normal, very bad dizziness or passing out, fast heartbeat, more thirst, seizures, feeling very tired or weak, not hungry, unable to pass urine or change in the amount of urine produced, dry mouth, dry eyes, or very bad upset stomach or throwing up.
- Feeling very tired or weak.
- Any unexplained bruising or bleeding.
- Swelling in the arms or legs.
- Fast breathing.
- A fast heartbeat.
- Call your doctor right away if you have signs of a blood clot like chest pain or pressure; coughing up blood; shortness of breath; swelling, warmth, numbness, change of color, or pain in a leg or arm; or trouble speaking or swallowing.
- Some people have had lung problems with Verzenio (abemaciclib). Sometimes, this has been deadly. Call your doctor right away if you have signs of lung problems like shortness of breath or other trouble breathing, cough that is new or worse, or fever.
What are some other side effects of Verzenio?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Constipation, diarrhea, stomach pain, upset stomach, throwing up, or feeling less hungry.
- Hair loss.
- Hair thinning.
- Feeling dizzy, tired, or weak.
- Dry mouth.
- Mouth irritation or mouth sores.
- Joint pain.
- Change in taste.
- Weight loss.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Verzenio?
- Store at room temperature in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about Verzenio (abemaciclib), please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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More about Verzenio (abemaciclib)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Imprints, Shape & Color Data
- Drug Interactions
- Pricing & Coupons
- En Español
- 3 Reviews
- Drug class: CDK 4/6 inhibitors
- FDA Alerts (1)
- FDA Approval History