Generic Name: Dofetilide (doe FET il ide)
Brand Name: Tikosyn
Medically reviewed by Drugs.com. Last updated on Jun 22, 2020.
- There is a risk that Tikosyn (dofetilide) may cause another type of abnormal heartbeat, which may be deadly. You will have to start and restart this drug in a setting where your heart will be watched nonstop. Talk with your doctor.
Uses of Tikosyn:
- It is used to keep a normal heartbeat in people who have a certain type of abnormal heartbeat (atrial fibrillation or atrial flutter).
- It may be used to turn atrial fibrillation or flutter into a normal heartbeat.
What do I need to tell my doctor BEFORE I take Tikosyn?
- If you have an allergy to dofetilide or any other part of Tikosyn (dofetilide).
- If you are allergic to Tikosyn (dofetilide); any part of Tikosyn (dofetilide); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
- If you have kidney disease.
- If you have any of these health problems: Long QT on ECG, low magnesium levels, or low potassium levels.
- If you are taking any drugs used for a heartbeat that is not normal.
- If you are taking any of these drugs: Cimetidine, dolutegravir, hydrochlorothiazide, itraconazole, ketoconazole, megestrol, prochlorperazine, trimethoprim, or verapamil.
- If you are taking any drugs that can cause a certain type of heartbeat that is not normal (prolonged QT interval). There are many drugs that can do this. Ask your doctor or pharmacist if you are not sure.
- If you are breast-feeding. Do not breast-feed while you take Tikosyn (dofetilide).
This is not a list of all drugs or health problems that interact with Tikosyn (dofetilide).
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Tikosyn (dofetilide) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Tikosyn?
- Tell all of your health care providers that you take Tikosyn (dofetilide). This includes your doctors, nurses, pharmacists, and dentists.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- You will need an ECG before starting Tikosyn (dofetilide) and during treatment. Talk with your doctor.
- Tell your doctor if you have too much sweat, fluid loss, throwing up, diarrhea, not hungry, or more thirst.
- If you drink grapefruit juice or eat grapefruit often, talk with your doctor.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using Tikosyn (dofetilide) while you are pregnant.
How is this medicine (Tikosyn) best taken?
Use Tikosyn (dofetilide) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Take with or without food.
- It is important that you do not miss or skip a dose of Tikosyn (dofetilide) during treatment.
- Keep taking Tikosyn (dofetilide) as you have been told by your doctor or other health care provider, even if you feel well.
What do I do if I miss a dose?
- Never make up a missed dose. Skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Chest pain or pressure.
- Shortness of breath.
- A type of abnormal heartbeat (prolonged QT interval) has happened with Tikosyn (dofetilide). Sometimes, this has led to another type of unsafe abnormal heartbeat (torsades de pointes). Call your doctor right away if you have a fast or abnormal heartbeat, or if you pass out.
What are some other side effects of Tikosyn?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Tikosyn?
- Store at room temperature.
- Keep lid tightly closed.
- Store in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time Tikosyn (dofetilide) is refilled. If you have any questions about Tikosyn (dofetilide), please talk with the doctor, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about Tikosyn (dofetilide)
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Images
- Drug Interactions
- Pricing & Coupons
- En Español
- 50 Reviews
- Generic Availability
- Drug class: group III antiarrhythmics