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Sitagliptin and Metformin Extended-Release Tablets

Generic name: Sitagliptin and Metformin Extended-Release Tablets [ sit-a-GLIP-tin-& met-FOR-min ]
Brand name: Janumet XR
Drug class: Antidiabetic combinations

Medically reviewed by Drugs.com. Last updated on Dec 2, 2023.

Warning

  • Rarely, metformin may cause an acid health problem (lactic acidosis). The risk is higher in people who have kidney problems, liver problems, heart failure, use alcohol, or take other drugs like topiramate. The risk is also higher in older people (65 or older) and in people who are having surgery, an exam or test with contrast, or other procedures. If lactic acidosis happens, it can lead to other health problems and can be deadly. Kidney tests may be done while taking this medicine (sitagliptin and metformin extended-release tablets).
  • Do not take this medicine (sitagliptin and metformin extended-release tablets) if you have a very bad infection, low oxygen, or a lot of fluid loss (dehydration).
  • Call your doctor right away if you have signs of too much lactic acid in the blood (lactic acidosis) like fast breathing, fast or slow heartbeat, a heartbeat that does not feel normal, very bad upset stomach or throwing up, feeling very sleepy, shortness of breath, feeling very tired or weak, very bad dizziness, feeling cold, or muscle pain or cramps.

Uses of Sitagliptin and Metformin Extended-Release Tablets:

What do I need to tell my doctor BEFORE I take Sitagliptin and Metformin Extended-Release Tablets?

This is not a list of all drugs or health problems that interact with this medicine (sitagliptin and metformin extended-release tablets).

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine (sitagliptin and metformin extended-release tablets) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Sitagliptin and Metformin Extended-Release Tablets?

How is this medicine (Sitagliptin and Metformin Extended-Release Tablets) best taken?

Use this medicine (sitagliptin and metformin extended-release tablets) as ordered by your doctor. Read all information given to you. Follow all instructions closely.

What do I do if I miss a dose?

Mounjaro, Ozempic, Rybelsus, metformin, Trulicity, Lantus, Tresiba, Basaglar, Levemir

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

What are some other side effects of Sitagliptin and Metformin Extended-Release Tablets?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Sitagliptin and Metformin Extended-Release Tablets?

Consumer Information Use and Disclaimer

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.