Generic name: Riluzole Suspension [ RIL-yoo-zole ]
Brand name: Tiglutik
Drug class: Miscellaneous central nervous system agents

Medically reviewed by Drugs.com. Last updated on Mar 16, 2023.

Uses of Riluzole Suspension:

• It is used to treat amyotrophic lateral sclerosis (ALS).

What do I need to tell my doctor BEFORE I take Riluzole Suspension?

• If you are allergic to riluzole suspension; any part of riluzole suspension; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
• If you have liver disease or raised liver enzymes.

This is not a list of all drugs or health problems that interact with riluzole suspension.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take riluzole suspension with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Riluzole Suspension?

• Tell all of your health care providers that you take riluzole suspension. This includes your doctors, nurses, pharmacists, and dentists.
• Have blood work checked as you have been told by the doctor. Talk with the doctor.
• If you are Japanese, use riluzole suspension with care. You could have more side effects.
• Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. You will need to talk about the benefits and risks to you and the baby.

How is this medicine (Riluzole Suspension) best taken?

Use riluzole suspension as ordered by your doctor. Read all information given to you. Follow all instructions closely.

• Take on an empty stomach. Take 1 hour before or 2 hours after meals.
• Take riluzole suspension at the same time of day.
• Keep taking riluzole suspension as you have been told by your doctor or other health care provider, even if you feel well.
• Shake well for at least 30 seconds before each use.
• Measure liquid doses carefully. Use the measuring device that comes with riluzole suspension. If there is none, ask the pharmacist for a device to measure riluzole suspension.
• If the adapter has not been put in the bottle when you get it, follow how to prepare the bottle as you have been told or read the package insert.
• Clean the measuring device as you have been told. If you have questions about cleaning the measuring device, talk with the doctor or pharmacist.
• Those who have feeding tubes may use riluzole suspension. Use as you have been told. Flush the feeding tube after riluzole suspension is given.

What do I do if I miss a dose?

• Take a missed dose as soon as you think about it, on an empty stomach.
• If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
• Do not take 2 doses at the same time or extra doses.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

• Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
• Signs of high blood pressure like very bad headache or dizziness, passing out, or change in eyesight.
• Lung problems have happened with riluzole suspension. Call your doctor right away if you have lung or breathing problems like trouble breathing, shortness of breath, or a cough that is new or worse.
• Very bad and sometimes deadly liver problems have happened with riluzole suspension. Call your doctor right away if you have signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
• Low white blood cell counts have rarely happened with riluzole suspension. This may lead to a higher chance of getting an infection. Tell your doctor if you have ever had a low white blood cell count. Call your doctor right away if you have signs of infection like fever, chills, or sore throat.

What are some other side effects of Riluzole Suspension?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

• Upset stomach.
• Stomach pain.
• Feeling dizzy, tired, or weak.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Riluzole Suspension?

• Store at room temperature protected from light. Store in a dry place. Do not store in a bathroom.
• Keep lid tightly closed.
• Store upright with the cap on.
• Do not freeze.
• After first opening, throw away any part not used after 15 days.
• Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
• Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

Consumer Information Use and Disclaimer

• If your symptoms or health problems do not get better or if they become worse, call your doctor.
• Do not share your drugs with others and do not take anyone else's drugs.
• Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about riluzole suspension, please talk with your doctor, nurse, pharmacist, or other health care provider.
• If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Frequently asked questions

• What is the difference between Rilutek, Tiglutik and Exservan?

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer