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Qtern

Generic Name: Dapagliflozin and Saxagliptin (dap a gli FLOE zin & sax a GLIP tin)
Brand Name: Qtern

Medically reviewed on July 4, 2018

Warning

  • Too much acid in the blood or urine (ketoacidosis) and very bad urinary tract infections (UTIs) have happened with Qtern (dapagliflozin and saxagliptin). Ketoacidosis can be deadly. Both of these health problems may need to be treated in a hospital. Talk with the doctor.
  • Do not take Qtern (dapagliflozin and saxagliptin) if you have type 1 diabetes. Do not take Qtern (dapagliflozin and saxagliptin) if you have ever had too much acid in the blood or urine caused by diabetes (diabetic ketoacidosis or DKA).
  • Get medical help right away if you have signs of too much acid in the blood (acidosis) like confusion; fast breathing; fast heartbeat; a heartbeat the does not feel normal; very bad stomach pain, upset stomach, or throwing up; feeling very sleepy; shortness of breath; or feeling very tired or weak.

Uses of Qtern:

  • It is used to lower blood sugar in patients with high blood sugar (diabetes).

What do I need to tell my doctor BEFORE I take Qtern?

  • If you have an allergy to Qtern (dapagliflozin and saxagliptin) or any part of Qtern (dapagliflozin and saxagliptin).
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you have any of these health problems: Acidic blood problem, bladder cancer, or type 1 diabetes.
  • If you have any of these health problems: Kidney disease or liver disease.
  • If you have low blood volume.
  • If you have a rare hereditary problem of galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption.
  • If you are taking pioglitazone.
  • If you are pregnant or may be pregnant. Do not take Qtern (dapagliflozin and saxagliptin) if you are pregnant.
  • If you are breast-feeding. Do not breast-feed while you take Qtern (dapagliflozin and saxagliptin).

This is not a list of all drugs or health problems that interact with Qtern (dapagliflozin and saxagliptin).

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Qtern (dapagliflozin and saxagliptin) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Qtern?

  • Tell all of your health care providers that you take Qtern (dapagliflozin and saxagliptin). This includes your doctors, nurses, pharmacists, and dentists.
  • Avoid driving and doing other tasks or actions that call for you to be alert until you see how Qtern (dapagliflozin and saxagliptin) affects you.
  • Low blood sugar can happen. The chance of low blood sugar may be raised when Qtern (dapagliflozin and saxagliptin) is used with other drugs for high blood sugar (diabetes). Signs may be dizziness, headache, feeling sleepy, feeling weak, shaking, a fast heartbeat, confusion, hunger, or sweating. Call your doctor right away if you have any of these signs. Follow what you have been told to do if you get low blood sugar. This may include taking glucose tablets, liquid glucose, or some fruit juices.
  • Do not drive if your blood sugar has been low. There is a greater chance of you having a crash.
  • To lower the chance of feeling dizzy or passing out, have your child rise slowly if your child has been sitting or lying down. Have your child be careful going up and down stairs.
  • Have blood work checked as you have been told by the doctor. Talk with the doctor.
  • This medicine may affect certain lab tests. Tell all of your health care providers and lab workers that you take Qtern (dapagliflozin and saxagliptin).
  • Talk with your doctor before you drink alcohol.
  • Follow the diet and workout plan that your doctor told you about.
  • It may be harder to control your blood sugar during times of stress like when you have a fever, an infection, an injury, or surgery. A change in level of physical activity or exercise and a change in diet may also affect your blood sugar. Talk with your doctor.
  • Check your blood sugar as you have been told by your doctor.
  • Bladder cancer has happened in a few more people taking Qtern (dapagliflozin and saxagliptin) than in those taking other drugs for diabetes. It is not known if this drug led to these cases of bladder cancer. Talk with your doctor.
  • Kidney problems have happened with Qtern (dapagliflozin and saxagliptin). Sometimes, kidney problems may need to be treated in the hospital. Dialysis may also be needed. Talk with your doctor.
  • A very bad and sometimes deadly pancreas problem (pancreatitis) has happened with other drugs like this one. Talk with your doctor.
  • Be careful in hot weather or while being active. Drink lots of fluids to stop fluid loss.
  • If loose stools (diarrhea) happen or you are throwing up, call your doctor. You will need to drink more fluids to keep from losing too much fluid.
  • If you are 65 or older, use Qtern (dapagliflozin and saxagliptin) with care. You could have more side effects.
  • This medicine is not for use in adults 75 years and older. It has not been shown to work in these people. Talk with the doctor.
  • Do not give to a child. Talk with your doctor.

How is this medicine (Qtern) best taken?

Use Qtern (dapagliflozin and saxagliptin) as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • Take with or without food.
  • Swallow whole. Do not chew, break, or crush.
  • Drink lots of noncaffeine liquids unless told to drink less liquid by your doctor.
  • Take Qtern (dapagliflozin and saxagliptin) at the same time of day.
  • To gain the most benefit, do not miss doses.
  • Keep taking Qtern (dapagliflozin and saxagliptin) as you have been told by your doctor or other health care provider, even if you feel well.

What do I do if I miss a dose?

  • Take a missed dose as soon as you think about it.
  • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
  • Do not take 2 doses at the same time or extra doses.

See also: Dosage Information (in more detail)

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of fluid and electrolyte problems like mood changes, confusion, muscle pain or weakness, a heartbeat that does not feel normal, very bad dizziness or passing out, fast heartbeat, more thirst, seizures, feeling very tired or weak, not hungry, unable to pass urine or change in the amount of urine produced, dry mouth, dry eyes, or very bad upset stomach or throwing up.
  • Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain.
  • Signs of a pancreas problem (pancreatitis) like very bad stomach pain, very bad back pain, or very bad upset stomach or throwing up.
  • Signs of a urinary tract infection (UTI) like blood in the urine, burning or pain when passing urine, feeling the need to pass urine often or right away, fever, lower stomach pain, or pelvic pain.
  • Strong odor to urine.
  • Any unexplained bruising or bleeding.
  • For females, vaginal yeast infection. Report itching or discharge.
  • For men, yeast infection of the penis. Report pain, swelling, rash, or discharge.
  • Heart failure has happened in people taking Qtern (dapagliflozin and saxagliptin). Tell your doctor if you have ever had heart failure or kidney problems. Call your doctor right away if you feel very tired or you have shortness of breath, a big weight gain, or swelling in the arms or legs.
  • Drugs like this one may cause joint pain that can be very bad and disabling. Call your doctor right away if you have very bad joint pain or any joint pain that does not go away.

What are some other side effects of Qtern?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

See also: Side effects (in more detail)

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Qtern?

  • Store at room temperature.
  • Store in a dry place. Do not store in a bathroom.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

Consumer information use

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
  • Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about Qtern (dapagliflozin and saxagliptin), please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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