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Fidaxomicin

Generic Name: Fidaxomicin (fye DAX oh mye sin)
Brand Name: Dificid

Uses of Fidaxomicin:

  • It is used to treat diarrhea caused by a bacterial infection called C diff.

What do I need to tell my doctor BEFORE I take Fidaxomicin?

  • If you are allergic to fidaxomicin; any part of fidaxomicin; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.

This medicine may interact with other drugs or health problems.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take fidaxomicin with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Fidaxomicin?

  • Tell all of your health care providers that you take fidaxomicin. This includes your doctors, nurses, pharmacists, and dentists.
  • Do not use longer than you have been told. A second infection may happen.
  • Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. You will need to talk about the benefits and risks to you and the baby.

How is this medicine (Fidaxomicin) best taken?

Use fidaxomicin as ordered by your doctor. Read all information given to you. Follow all instructions closely.

All products:

  • Take with or without food.
  • Keep taking fidaxomicin as you have been told by your doctor or other health care provider, even if you feel well.

Liquid (suspension):

  • Your pharmacist will need to mix fidaxomicin before you get it.
  • Take fidaxomicin out of the refrigerator 15 minutes before each dose. Do not heat or microwave.
  • Shake well before use.
  • Measure liquid doses carefully. Use the measuring device that comes with fidaxomicin. If there is none, ask the pharmacist for a device to measure fidaxomicin.
  • Put the cap back on after you are done using your dose.

What do I do if I miss a dose?

  • Take a missed dose as soon as you think about it.
  • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
  • Do not take 2 doses at the same time or extra doses.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Shortness of breath.
  • Black, tarry, or bloody stools.
  • Throwing up blood or throw up that looks like coffee grounds.
  • Feeling very tired or weak.
  • Fever or chills.

What are some other side effects of Fidaxomicin?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

For all patients taking fidaxomicin:

Children:

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Fidaxomicin?

Tablets:

  • Store at room temperature in a dry place. Do not store in a bathroom.

Liquid (suspension):

  • Store in a refrigerator. Do not freeze.
  • After fidaxomicin is mixed, throw away any part not used after 12 days.

All products:

  • Store in original container.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

Consumer information use

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about fidaxomicin, please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.