Generic Name: ethionamide (e-THYE-on-am-ide)
Brand Name: Trecator
Ethionamide is used for:
Treating tuberculosis (TB) infections in combination with other medicines. It may also be used for other conditions as determined by your doctor.
Ethionamide is an antibacterial agent. It works by inhibiting or stopping the growth of TB cells, which results in cell death.
Do NOT use ethionamide if:
- you are allergic to any ingredient in ethionamide
- you have severe liver disease
Contact your doctor or health care provider right away if any of these apply to you.
Before using ethionamide:
Some medical conditions may interact with ethionamide. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have diabetes, liver problems, or vision problems
Some MEDICINES MAY INTERACT with ethionamide. However, no specific interactions with ethionamide are known at this time.
This may not be a complete list of all interactions that may occur. Ask your health care provider if ethionamide may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use ethionamide:
Use ethionamide as directed by your doctor. Check the label on the medicine for exact dosing instructions. Check the label on the medicine for exact dosing instructions.
- Ethionamide may be taken with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
- Ethionamide should be taken in combination with other medicines.
- If you miss a dose of ethionamide and you are taking it regularly, take it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to catch up, unless advised by your health care provider. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use ethionamide.
Important safety information:
- Ethionamide may cause dizziness, lightheadedness, or fainting. Alcohol, hot weather, exercise, and fever can increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Also, sit or lie down at the first sign of dizziness, lightheadedness, or weakness.
- Avoid drinking alcohol or taking other medications that cause drowsiness (eg, sedatives, tranquilizers) while taking ethionamide. Ethionamide will add to the effects of alcohol and other depressants. Ask your pharmacist if you have questions about which medicines are depressants.
- Ethionamide may cause increased sensitivity to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to ethionamide. Use a sunscreen or wear protective clothing if you must be outside for a prolonged period.
- Ethionamide is effective only against bacteria. It is not effective for treating viral infections (eg, the common cold).
- It is important to use ethionamide for the full course of treatment. Failure to do so may decrease the effectiveness of ethionamide and may increase the risk that the bacteria will no longer be sensitive to ethionamide and will not be able to be treated by this or certain other antibiotics in the future.
- You may be required to take a vitamin B supplement while taking ethionamide.
- Diabetes patients - Ethionamide may affect your blood sugar. Check blood sugar levels closely and ask your doctor before adjusting the dose of your diabetes medicine.
- LAB TESTS, including blood sugar, thyroid function tests, liver function tests, and vision tests, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
- Ethionamide should not be used in CHILDREN younger than 12 years of age. Safety and effectiveness in this age group have not been confirmed. In some cases, use in children may be warranted if other medicines are not effective or are not tolerated.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using ethionamide during pregnancy. It is unknown if ethionamide is excreted in breast milk. If you are or will be breast-feeding while you are using ethionamide, check with your doctor or pharmacist to discuss the risks to your baby.
Possible side effects of ethionamide:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Diarrhea; dizziness; drowsiness; headache; increased salivation; loss of appetite; metallic taste; mouth sores; nausea; restlessness; stomach pain; vomiting; weight loss.
Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); change in sense of smell; depression; easy bruising or bleeding; low blood sugar (eg, increased heartbeat, headache, chills, sweating, tremor, increased hunger, changes in vision, nervousness, weakness, dizziness, drowsiness, fainting); tingling of hands or feet; vision changes (eg, loss of vision); yellowing of the skin or eyes.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.Proper storage of ethionamide:
Store ethionamide at room temperature, between 68 and 77 degrees F (20 and 25 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Keep ethionamide out of the reach of children and away from pets.
- If you have any questions about ethionamide, please talk with your doctor, pharmacist, or other health care provider.
- Ethionamide is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take ethionamide or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about ethionamide. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to ethionamide. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using ethionamide.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
More about ethionamide
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
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- Drug class: nicotinic acid derivatives