Skip to Content

Ethionamide Pregnancy and Breastfeeding Warnings

Ethionamide is also known as: Trecator, Trecator-SC

Medically reviewed on Jul 10, 2018

Ethionamide Pregnancy Warnings

Animal studies have revealed evidence of teratogenicity with high doses. There are no controlled data in human pregnancy.

US FDA pregnancy category Not Assigned: The US FDA has amended the pregnancy labeling rule for prescription drug products to require labeling that includes a summary of risk, a discussion of the data supporting that summary, and relevant information to help health care providers make prescribing decisions and counsel women about the use of drugs during pregnancy. Pregnancy categories A, B, C, D, and X are being phased out.

Use should be avoided.

US FDA pregnancy category: Not assigned.

Risk Summary: This drug has teratogenic potential in animal models given doses in excess of those recommended in humans.

Comments:
-Treatment should be withheld in patients likely to become pregnant during therapy unless this drug considers it to be an essential part of treatment.
-The effects on labor and delivery are unknown.

See references

Ethionamide Breastfeeding Warnings

Benefit should outweigh risk.

Excreted into human milk: Unknown
Excreted into animal milk: Data not available

Comment: Breastfed infants should be monitored for adverse events.

See references

References for pregnancy information

  1. Briggs GG, Freeman RK, Yaffe SJ.. "Drugs in Pregnancy and Lactation. 6th ed." Philadelphia, PA: Lippincott Williams & Wilkins (2002):
  2. "Product Information. Trecator-SC (ethionamide)." Wyeth-Ayerst Laboratories, Philadelphia, PA.

References for breastfeeding information

  1. Briggs GG, Freeman RK, Yaffe SJ.. "Drugs in Pregnancy and Lactation. 6th ed." Philadelphia, PA: Lippincott Williams & Wilkins (2002):
  2. "Product Information. Trecator-SC (ethionamide)." Wyeth-Ayerst Laboratories, Philadelphia, PA.
  3. United States National Library of Medicine "Toxnet. Toxicology Data Network. Available from: URL: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT." ([cited 2013 -]):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Hide