Medically reviewed by Drugs.com. Last updated on Jul 3, 2020.
- This medicine is a strong pain drug that can put you at risk for addiction, abuse, and misuse. Misuse or abuse of Dsuvia (sufentanil sublingual tablets) can lead to overdose and death. Talk with your doctor.
- You will be watched closely to make sure you do not misuse, abuse, or become addicted to Dsuvia (sufentanil sublingual tablets).
- This medicine may cause very bad and sometimes deadly breathing problems. Call your doctor right away if you have slow, shallow, or trouble breathing.
- The chance of very bad and sometimes deadly breathing problems may be greater when you first start Dsuvia (sufentanil sublingual tablets) or anytime your dose is raised.
- Even one dose of Dsuvia (sufentanil sublingual tablets) may be deadly if it is taken by someone else or by accident, especially in children. If Dsuvia (sufentanil sublingual tablets) is taken by someone else or by accident, get medical help right away.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- This medicine has an opioid drug in it. Severe side effects have happened when opioid drugs were used with benzodiazepines or other drugs that may make you drowsy or slow your actions. This includes slow or troubled breathing and death. Benzodiazepines include drugs like alprazolam, diazepam, and lorazepam. Benzodiazepines may be used to treat many health problems like anxiety, trouble sleeping, or seizures. If you have questions, talk with your doctor.
- Many drugs interact with Dsuvia (sufentanil sublingual tablets) and can raise the chance of side effects like deadly breathing problems. Talk with your doctor and pharmacist to make sure it is safe to use Dsuvia (sufentanil sublingual tablets) with all of your drugs.
- Do not take with alcohol or products that have alcohol. Unsafe and sometimes deadly effects may happen.
- Get medical help right away if you feel very sleepy, very dizzy, or if you pass out. Caregivers or others need to get medical help right away if the patient does not respond, does not answer or react like normal, or will not wake up.
- Using Dsuvia (sufentanil sublingual tablets) for a long time during pregnancy may lead to withdrawal in the newborn baby. This can be life-threatening. Talk with the doctor.
Uses of Dsuvia:
- It is used to ease pain.
What do I need to tell my doctor BEFORE I take Dsuvia?
- If you have an allergy to sufentanil or any other part of Dsuvia (sufentanil sublingual tablets).
- If you are allergic to Dsuvia (sufentanil sublingual tablets); any part of Dsuvia (sufentanil sublingual tablets); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
- If you have any of these health problems: Lung or breathing problems like asthma, trouble breathing, or sleep apnea; high levels of carbon dioxide in the blood; or stomach or bowel block or narrowing.
- If you are taking any of these drugs: Buprenorphine, butorphanol, nalbuphine, or pentazocine.
- If you have taken certain drugs for depression or Parkinson's disease in the last 14 days. This includes isocarboxazid, phenelzine, tranylcypromine, selegiline, or rasagiline. Very high blood pressure may happen.
- If you are taking any of these drugs: Linezolid or methylene blue.
- If the patient is a child. Do not give Dsuvia (sufentanil sublingual tablets) to a child.
This is not a list of all drugs or health problems that interact with Dsuvia (sufentanil sublingual tablets).
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Dsuvia (sufentanil sublingual tablets) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Dsuvia?
- Tell all of your health care providers that you take Dsuvia (sufentanil sublingual tablets). This includes your doctors, nurses, pharmacists, and dentists.
- Avoid driving and doing other tasks or actions that call for you to be alert until you see how Dsuvia (sufentanil sublingual tablets) affects you.
- To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. Be careful going up and down stairs.
- This medicine may raise the chance of seizures in some people, including people who have had seizures in the past. Talk to your doctor to see if you have a greater chance of seizures while taking Dsuvia (sufentanil sublingual tablets).
- Do not take Dsuvia (sufentanil sublingual tablets) with other strong pain drugs or if you are using a pain patch without talking to your doctor first.
- Do not use longer than you have been told by the doctor.
- If you are 65 or older, use Dsuvia (sufentanil sublingual tablets) with care. You could have more side effects.
- This medicine may cause harm to the unborn baby if you take it while you are pregnant. If you are pregnant or you get pregnant while taking Dsuvia (sufentanil sublingual tablets), call your doctor right away.
- Tell your doctor if you are breast-feeding or plan to breast-feed. This medicine passes into breast milk and may harm your baby.
How is this medicine (Dsuvia) best taken?
Use Dsuvia (sufentanil sublingual tablets) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Place under tongue and let dissolve all the way. Do not chew, suck or swallow tablet.
- Do not eat or drink for at least 10 minutes after taking Dsuvia (sufentanil sublingual tablets).
- Try not to talk much for 10 minutes after taking Dsuvia (sufentanil sublingual tablets).
- If you have a very dry mouth, use ice chips before taking Dsuvia (sufentanil sublingual tablets).
- This medicine will be given to you by a doctor.
What do I do if I miss a dose?
- Call your doctor to find out what to do.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Very bad dizziness or passing out.
- Slow heartbeat.
- Feeling confused.
- Trouble breathing, slow breathing, or shallow breathing.
- Noisy breathing.
- Chest pain or pressure or a fast heartbeat.
- A severe and sometimes deadly problem called serotonin syndrome may happen if you take Dsuvia (sufentanil sublingual tablets) with certain other drugs. Call your doctor right away if you have agitation; change in balance; confusion; hallucinations; fever; fast or abnormal heartbeat; flushing; muscle twitching or stiffness; seizures; shivering or shaking; sweating a lot; severe diarrhea, upset stomach, or throwing up; or severe headache.
- Taking an opioid drug like Dsuvia (sufentanil sublingual tablets) may lead to a rare but very bad adrenal gland problem. Call your doctor right away if you have very bad dizziness or passing out, very bad upset stomach or throwing up, or if you feel less hungry, very tired, or very weak.
- Long-term use of an opioid drug may lead to lower sex hormone levels. Call your doctor if you have a lowered interest in sex, fertility problems, no menstrual period (women), or change in sex ability (men).
What are some other side effects of Dsuvia?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Upset stomach or throwing up.
- Feeling sleepy.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Dsuvia?
- This medicine will be given in a hospital or doctor's office. If stored at home, follow how to store as you were told by the doctor or pharmacist.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about Dsuvia (sufentanil sublingual tablets), please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Frequently asked questions
- What is the Dsuvia REMS program?
- How do you take the Dsuvia (sufentanil) tablet?
- Is Dsuvia (sufentanil) a controlled substance?
More about Dsuvia (sufentanil)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- Pricing & Coupons
- Drug class: narcotic analgesics
- FDA Approval History
- Other brands
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Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.