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Cisplatin

Generic Name: Cisplatin (SIS pla tin)

Medically reviewed by Drugs.com. Last updated on Feb 10, 2019.

Warning

  • This medicine may cause kidney problems like kidney failure. You will need to make sure you are not dehydrated before, during, and after doses of cisplatin. Drink lots of noncaffeine liquids and have your blood work checked as you have been told by your doctor.
  • This medicine may cause nerve problems. These nerve problems can get worse the more times you get cisplatin. Sometimes, these nerve problems have not gone back to normal. If you have questions, talk with the doctor.
  • This medicine may cause upset stomach or throwing up. Other drugs will be given before cisplatin to help with this.
  • This medicine may lower the ability of the bone marrow to make blood cells that the body needs. If blood cell counts get very low, this can lead to bleeding problems, infections, or anemia. Some infections have been severe and even deadly. If you have questions, talk with the doctor.

Uses of Cisplatin:

See also: Alunbrig
  • It is used to treat ovarian cancer.
  • It is used to treat testicular cancer.
  • It is used to treat bladder cancer.
  • It may be given to you for other reasons. Talk with the doctor.

What do I need to tell my doctor BEFORE I take Cisplatin?

  • If you have an allergy to cisplatin or any other part of cisplatin.
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you are breast-feeding. Do not breast-feed while you take cisplatin.

This medicine may interact with other drugs or health problems.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take cisplatin with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Cisplatin?

  • Tell all of your health care providers that you take cisplatin. This includes your doctors, nurses, pharmacists, and dentists.
  • Have blood work checked as you have been told by the doctor. Talk with the doctor.
  • Have a hearing test before starting cisplatin and while you take cisplatin.
  • You may bleed more easily. Be careful and avoid injury. Use a soft toothbrush and an electric razor.
  • You may have more of a chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu. Some infections have been very bad and even deadly.
  • Talk with your doctor before getting any vaccines. Use of some vaccines with cisplatin may either raise the chance of an infection or make the vaccine not work as well.
  • Very bad and sometimes deadly allergic reactions have rarely happened. Talk with your doctor.
  • Problems with eyesight have happened with cisplatin. This includes loss of eyesight. If you have questions, talk with the doctor.
  • Other types of cancer may rarely happen later in life.
  • If you are 65 or older, use cisplatin with care. You could have more side effects.
  • Use with care in children. Talk with the doctor.
  • This medicine may affect fertility. Fertility problems may lead to not being able to get pregnant or father a child. Talk with the doctor.
  • Females treated with cisplatin may go through menopause at a younger age than normal. Talk with the doctor.
  • If you are a man and have sex with a female who could get pregnant, use birth control to protect her from pregnancy while you take this drug and for 11 months after your last dose.
  • If you are a man and your sex partner gets pregnant while you take cisplatin or within 11 months after your last dose, call your doctor right away.
  • This medicine may cause harm to the unborn baby if you take it while you are pregnant.
  • If you are able to get pregnant, a pregnancy test will be done to show that you are NOT pregnant before starting cisplatin. Talk with your doctor.
  • Use birth control to prevent pregnancy while taking cisplatin and for 14 months after your last dose.
  • If you get pregnant while taking cisplatin or within 14 months after your last dose, call your doctor right away.

How is this medicine (Cisplatin) best taken?

Use cisplatin as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • It is given as an infusion into a vein over a period of time.

What do I do if I miss a dose?

  • Call your doctor to find out what to do.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
  • Signs of bleeding like throwing up blood or throw up that looks like coffee grounds; coughing up blood; blood in the urine; black, red, or tarry stools; bleeding from the gums; vaginal bleeding that is not normal; bruises without a reason or that get bigger; or any bleeding that is very bad or that you cannot stop.
  • Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain.
  • Feeling very tired or weak.
  • Ringing in the ears, hearing loss, or any other changes in hearing.
  • A burning, numbness, or tingling feeling that is not normal.
  • Very bad dizziness or passing out.
  • A fast heartbeat.
  • Change in eyesight or in the way you see color.
  • This medicine may cause tissue damage if the drug leaks from the vein. Tell your nurse if you have any redness, burning, pain, swelling, blisters, skin sores, or leaking of fluid where the drug is going into your body.

What are some other side effects of Cisplatin?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Hair loss.
  • Diarrhea, throwing up, upset stomach, and feeling less hungry are common with cisplatin. If these happen, talk with your doctor about ways to lower these side effects. Call your doctor right away if any of these effects bother you, do not get better, or get very bad.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Cisplatin?

  • If you need to store cisplatin at home, talk with your doctor, nurse, or pharmacist about how to store it.

Consumer information use

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
  • Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about cisplatin, please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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