What is the difference between Mvasi and Avastin?
Mvasi (bevacizumab-awwb) is a biosimilar to Avastin (bevacizumab).
Mvasi is not interchangeable with Avastin. The prescriber must write a prescription specifically for Mvasi.
A biosimilar, according to the FDA, is a biological product that is highly similar to an FDA-approved biological product, known as a reference product (in this case Avastin), and has no clinically meaningful differences in terms of safety and effectiveness.
See Biosimilar and Interchangeable Biologics: More Treatment Choices
Mvasi has the same approved indications as Avastin, with the exception of hepatocellular carcinoma.
| Avastin | Mvasi | |
|---|---|---|
| Generic Name | bevacizumab | bevacizumab-awwb |
| How Supplied |
|
|
| Indications |
|
|
Mvasi was approved in 2017 as the first biosimilar to Avastin. A second Avastin biosimilar called Zirabev (bevacizumab-bvzr) was approved in 2019, and a third called Alymsys (bevacizumab-maly) was approved in 2022.
Related questions
- How long does chemo take? Sessions, cycles, and recovery time?
- What’s the difference between Eylea, Eylea HD, and Avastin?
- What are biologic drugs and how do they work?
Read next
What are monoclonal antibodies?
Monoclonal antibodies (mAbs) are man-made proteins that mimic the natural antibodies produced by our immune systems. Monoclonal antibodies can be formulated into medicines to treat various types of illnesses, such as cancer, rheumatoid arthritis or psoriasis.
Continue reading
What are biosimilar drugs and how do they compare to biologics?
A biosimilar is a biological product that is similar to a reference biologic (usually the originally approved product) and for which there are no clinically meaningful differences in terms of safety, purity, and potency. The most recently approved biosimilar is Starjemza (ustekinumab-hmny), an interchangeable biosimilar to Stelara, cleared by the FDA on May 22, 2025.
Continue reading
What are anti-VEGF drugs (VEGF inhibitors)?
Anti-VEGF drugs slow the abnormal growth of blood vessels associated with certain cancers and degenerative eye conditions, such as age-related macular degeneration. Anti-VEGF stands for anti-vascular endothelial growth factor. Continue reading
See also:
Aimovig
Learn about Aimovig (erenumab-aooe) a once-monthly, injectable medication that can be ...
Botox
Botox is used for cosmetic purposes and to treat overactive bladder symptoms, urinary incontinence ...
Enhertu
Enhertu is a treatment for breast cancer, stomach cancer, and non-small cell lung cancer with HER2 ...
Nurtec ODT
Nurtec ODT (rimegepant) is used to treat acute migraines and prevent episodic migraines, by ...
Depakote
Depakote is used to treat various types of seizure disorders. Learn about side effects ...
Topamax
Topamax (topiramate) is used to prevent seizures in adults and children and to prevent migraine ...
Emgality
Emgality (galcanezumab-gnlm) is a CGRP antagonist for the preventive treatment of migraine and for ...
Timolol
Timolol is used for angina, heart attack, high blood pressure, migraine, migraine prevention
Valproic acid
Valproic acid is used for bipolar disorder, cluster-tic syndrome, epilepsy, headache ...
Divalproex sodium
Divalproex sodium is used for bipolar disorder, borderline personality disorder, cyclothymic ...
Related medical questions
- What biosimilars have been approved in the United States?
- Is small cell or non-small cell lung cancer worse?
- Is non-small cell lung cancer hereditary?
- How aggressive is non-small cell lung cancer?
- Does smoking cause non-small cell lung cancer?
- What type of lung cancer is Vizimpro used to treat?
- What type of cancer is Tecentriq used to treat?
- How long does it take for Keytruda to work?
- Why give Taxol (Paxel) before carboplatin?
- What is the difference between Opdivo and Keytruda?
- Pembrolizumab vs. nivolumab: How do they compare?
- What is Paxel called in the USA?
- How effective is Lumakras, what's the survival rate?
- Are there cost-saving programs for Tecentriq?
- How effective is Tabrecta?
- Opdivo vs Opdivo Qvantig: What is the Difference?
- How does erlotinib work (mechanism of action)?
- How effective is atezolizumab (Tecentriq)?
- Is atezolizumab (Tecentriq) a chemotherapy or immunotherapy drug?
- How long can I take Gilotrif (afatinib) for?
- Will Tabrecta cure lung cancer?
- How long do you take Alecensa for?
- Is Gilotrif (afatinib) a chemotherapy drug?
- How effective is Alecensa for ALK-positive NSCLC?
- Is Tabrecta a chemotherapy drug?
- How does Retevmo work?
- How does pemetrexed work?
- What is the mechanism of action for Alecensa (alectinib)?
- Can Tarceva (erlotinib) cure lung cancer?
- How do Exkivity and Rybrevant compare for NSCLC?
Drug information
Related support groups
- Bevacizumab (5 questions, 7 members)
- Avastin (9 questions, 46 members)
- Mvasi (3 questions, 5 members)
- Non-Small Cell Lung Cancer (53 questions, 73 members)
- Renal Cell Carcinoma (32 questions, 103 members)
- Colorectal Cancer (22 questions, 53 members)
- Cervical Cancer (6 questions, 25 members)
- Glioblastoma Multiforme (1 questions, 27 members)