This question has also been asked and answered here: Allegra vs Zyrtec: What's the difference?
If your allergy is particularly bad then yes you can. I would say avoid unless you absolutely have to take both Allegra and Zyrtec on the same day. Apart from my reservations, there are no known interactions between these medicines. However, it does not mean that no interactions exist so if you do experience any odd symptoms please see your doctor.
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