Aczone Side Effects
Generic Name: dapsone topical
Note: This document contains side effect information about dapsone topical. Some of the dosage forms listed on this page may not apply to the brand name Aczone.
Some side effects of Aczone may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
For the Consumer
Applies to dapsone topical: topical gel/jelly
Along with its needed effects, dapsone topical (the active ingredient contained in Aczone) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor as soon as possible if any of the following side effects occur while taking dapsone topical:Incidence not known
- Attempts at killing oneself
- body aches or pain
- darkened urine
- dryness or soreness of throat
- fast heartbeat
- loss of appetite
- pains in stomach, side, or abdomen, possibly radiating to the back
- runny nose
- stomach pain
- tender, swollen glands in neck
- tonic and clonic muscle movements
- trouble swallowing
- voice changes
- vomiting, severe
- feeling sad or empty
- feeling that others are watching you or controlling your behavior
- feeling that others can hear your thoughts
- feeling, seeing, or hearing things that are not there
- loss of interest or pleasure
- severe mood or mental changes
- trouble concentrating
- unusual behavior
Some side effects of dapsone topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:More common
- flushing, redness of skin
- unusually warm skin
- difficulty breathing
- ear congestion
- itching skin
- general feeling of discomfort or illness
- joint pain
- joint sprain
- muscle aches and pains
- pain or tenderness around eyes and cheekbones
- shortness of breath or trouble breathing
- sore throat
- stuffy nose
- tightness of chest or wheezing
- trouble sleeping
- unusual tiredness or weakness
- Facial swelling
For Healthcare Professionals
Applies to dapsone topical: topical gel
Local side effects for dapsone topical (the active ingredient contained in Aczone) in relation to the vehicle alone have frequently included dryness (16% vs. 17%), erythema (13% vs. 14%), burning (1% vs. 2%), and pruritus (1% vs. 1%) at the site of application.
Respiratory side effects for dapsone topical (the active ingredient contained in Aczone) in relation to the vehicle alone have included nasopharyngitis (5% vs. 6%), upper respiratory tract infection (3% vs. 3%), sinusitis (2% vs. 1%), pharyngitis (2% vs. 2%), and cough (2% vs. 2%).
Other side effects for dapsone topical (the active ingredient contained in Aczone) in relation to the vehicle alone have included pyrexia (1% vs. 1%), influenza (1% vs. 1%), and headache (4% vs. 4%). Facial swelling (1 case) resulting in discontinuation of treatment has been reported.
Musculoskeletal side effects for dapsone topical (the active ingredient contained in Aczone) in relation to the vehicle alone have included joint sprain (1% vs. 1%).
Nervous system side effects have included tonic clonic movements.
Clinical trials (n=2372) reported 9 and 2 patients treated with dapsone topical (the active ingredient contained in Aczone) to have depression and psychosis, respectively.
Psychiatric side effects have included suicide attempt, depression, and psychosis.
Gastrointestinal side effects have included abdominal pain, severe vomiting, and pancreatitis.
Hematologic side effects have included increased reticulocyte count and decreased hemoglobin level in a single patient with G6PD deficiency who had a complete blood count performed prior to initiation of treatment.
More about Aczone (dapsone topical)
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