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5-HTP User Reviews & Ratings (Page 2)

5-HTP has an average rating of 6.6 out of 10 from a total of 147 reviews on Drugs.com. 55% of reviewers reported a positive experience, while 24% reported a negative experience.

Reviews for 5-HTP

  • Aano
  • November 15, 2019

For Anxiety "Wanted to share my experience with 5-HTP in case it helped anyone. I've used 50mg once daily for the past few years to help with depression/anxiety/sleep issues and it did help for a while, especially with sleeping better. Unfortunately, I now have to stop after realizing it has been making symptoms worse after taking it probably too long. Too much serotonin in your system will cause worse anxiety, so just know that just because this product is sold in the health food section - I would definitely consider it a natural drug you should do your research on. If the dose is too high it will cause worse anxiety issues. This drug can also interact with other medications and alcohol, so just be aware. Buy a brand with good reviews and figure out what time of day taking it works best for you. It made me a bit too relaxed to take it in the morning, but taking it right before bed caused crazy dreams - so taking it with dinner at least a few hours before bed worked best for me personally."

7 / 10
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87 Report
  • Hotel...
  • April 7, 2017

For Anxiety "I've usually been able to pull myself out of episodes of anxiety/depression through CBT and other non-drug strategies but this was becoming harder and harder to do, especially after the death of my dad. Long story short - I looked into non-pharmaceutical supplements because I'd sooner be sad and anxious than foggy and addicted. 5HTP helped me and I have experienced no side effects. I take it at night, am able to sleep well with no residual grogginess in the morning. Am I a happy person now? No, but I'm not miserable and my interest in life is increasing. I'm more optimistic which in itself is a big deal and I'm finding that I'm not going down the 'dark path' of negative thoughts as often or for as long."

7 / 10
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122 Report
  • Red...
  • Taken for less than 1 month
  • May 24, 2017

For Anxiety "5htp has changed my life ! After trying tons of antidepressant medications none of them are working so I decided to try something natural five HTP is amazing and helps with sleep, helps with stress and just makes you feel like a wonderful kind of you. A good feeling all the time, I love it and I recommend it to everybody"

10 / 10
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116 Report
  • robnz
  • October 19, 2016

For Anxiety "for those who may not be aware Could a Gene Mutation be causing your depression or bipolar? i highly recommend researching this -With the MTHFR gene mutation you may not be able to make the enough of the active form of the vitamin folate/ vit b9 needed to make the neurotransmitters serotonin and dopamine causing mental health problems- google: balancingbrainchemistry the treatment for this gene mutation is taking mentholated b12 and and methyl folate/b9"

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120 Report
  • T G
  • Taken for less than 1 month
  • July 1, 2019

For Anxiety "33 year old male. Started having nocturnal anxiety attacks. Happened for a couple weeks. Would wake up after falling asleep (usually with a late meal) not being able to breath, chest pain, feeling heavy, and weak. I actually went to the ER the first night it happened because I thought I was dying. Doctor originally thought the issue was caused by stomach acid getting into lungs but antacids did nothing. Doctor then suggested 5 HTP a week later. No more attacks (other than the one night I forgot to take the pill) after I started taking 100mg before bed. If you plan on taking 5HTP, get quality product (don’t go cheap trying to save a dollar). Some of the lower quality stuff can have its own side effects. Good luck."

10 / 10
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82 Report

Are you taking this medicine?

  • Solveig
  • February 2, 2017

For Anxiety "I am 24 and have suffered from depression and severe anxiety since I was a young teenager. I've attempted suicide and been on tons of antidepressants which didn't help. My brother researched natural medicine and found this to treat his depression plus st johns wort in the mornings, and I decided to try it per his recommendation. So glad I found this. I finally feel like life is worth living and have hope in the future again. I take the 5-htp at night because it knocks me out and gives me vivid dreams. I only take 100mg daily."

10 / 10
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109 Report
  • Anonymous
  • Taken for 1 to 6 months
  • August 13, 2012

For Anxiety "Switched from Seroquel 50mg/Prozac 20mg/ to just 50mgs of 5-HTP at night. Works okay, no side effects, improves my concentration, mood has improved, unlike the effects of mood blunting SSRI's, appetite decreased, have lost 6kgs since starting treatment. Anxiety generally at bay, still need to take a morning dose of propranolol (20mg), works well for insomnia (especially rebound insomnia associated with anti-psychotic withdrawal, am usually asleep within an hour/hour and a half of dosing, no withdrawal symptoms on cessation. Haven't felt this good in years!"

10 / 10
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155 Report
  • Carbear
  • November 6, 2017

For Anxiety "I have been on anxiolytics and antidepressants for 15 years. I wanted to give them up and go natural. I must say, I can not believe it has not been recommended to me before! I guess it's because it takes away from their business. My first 200 mg dose, I became a little nauseous but I hadn't eaten before taking it. I am amazed at how my mood has improved. I also used to smoke marijuana and when I stopped, I missed the way it gave me patience with my children. I would smoke and all of the sudden, the messes and yelling didn't bother me. Unfortunately it's not legal in texas so I needed to stop. After two months of irritability, I have now found some thing natural and legal that gave me my patience back and my children their loving mother back!"

10 / 10
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97 Report
  • Anonymous
  • August 24, 2018

For Anxiety "5HTP has helped me manage my anxiety and after years of PTSD related nightmares, I'm finally sleeping properly. It's helped massively with suicidal ideation, even during better times the intrusive thoughts were always lurking. For the first 7-10 days I did have quite noticeable side effects, headaches, feeling nauseous and shaking a little but I continued to take it as TBH it was better than side effects of prescribed anti depressants I've experienced in the past , which is probably not the most sensible but now I'm happy I did. I take this with a combination of L-tyrosine and B vitamins and magnesium. Probably also worth mentioning is the ease I've managed to sort out my binge eating, I've lost 13kg in the last 4 months which has been a fantastic thing for me and now my BMI is back in the healthy range."

9 / 10
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86 Report
  • David...
  • February 2, 2015

For Anxiety "I took 5-HTP for depression, anxiety and insomnia and it worked like a charm for the first night. I took another one the next morning and I felt really weird and worsened my symptoms. I took another one the same night and ended up with serotonin syndrome. Be careful whilst taking this. Make sure you space out your intake as it's terrifying if it goes wrong. I didn't have to go to a hospital, however I had mood changes every 5 mins, heavy brain fog, heavy depression and suicidal thoughts. Took me around a week to clear up again. I'm scared to take another one fearing the outcome."

8 / 10
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123 Report
  • Hugh...
  • June 21, 2015

For Anxiety "Supplements vary wildly in potency and quality from brand to brand. The way this stuff works for me is to put 50 mg of powder into a quart of water and drink it throughout the day. You do not want to get a huge spike of this stuff into your blood stream that later shoots down. I have great results for several months this way."

8 / 10
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114 Report
  • Nutty...
  • Taken for 10 years or more
  • April 9, 2020

For Anxiety "5-HTP in my experience of taking it (10yrs+) It has absolutely been down to dosage.. I have had terrible side effects with the lowest "Recommended Dosages". Sweats/Shakes/Anxiety through the roof/Nightmares/Insomnia... Until I started at the lowest dose I could buy 50mg Slow/Timed Release type in the morning & had no unwanted side effects.. I have increased my dosage to 100mg daily if having a bad episode & usually after say 6wks- 3 months I have gradually reduced back down to 50mg over 2-3wks- ie: Taking 100mg Mon-Wed-Fri-Sun & 50mg on the other day's then 50mg for 2 days & 100mg on the 3rd day & so on...Obviously I am not a medical professional I am just sharing my experience here...I suffer from PTSD/Depression/Anxiety & 2 out of my 3 pregnancies ended in serious episodes of PND..(Suicidal Psychosis) I self medicated for many years & been prescribed many Anti-Depresants/Anti-Psychotics all of which have given me the worst side effects listed."

10 / 10
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63 Report
  • Hillccs
  • August 1, 2015

For Anxiety "5- HTP has really helped me after being unable to tolerate side effects from Zoloft. I tapered off Zoloft and once I stopped I switched directly to 50 mg of 5-HTP in morning and 50 at night. I have had little to no side effects switching to the supplement. Very thankful to find 5 htp"

10 / 10
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106 Report
  • w1ll1...
  • Taken for 1 to 6 months
  • February 17, 2019

For Anxiety "Was diagnosed with anxiety and depression about 4 years ago, went down the SSRI route on and off. With SSRI you felt like I was just going with the motions like being on auto pilot with no real get up and go. I switched to 5HTP at 50mg for a few weeks and noticed a difference, no side effects, eating healthy, getting up early, getting out and about and just feeling better about myself, mistakes that I used to think about are now in the past. Only negative I noticed was that the effects seem to differ from different brands of 5HTP. I don’t go for a cheaper option that offered twice the strength, go for a smaller quantity and try different brands until you find the most effective"

8 / 10
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69 Report
  • Anony...
  • Taken for less than 1 month
  • April 3, 2018

For Anxiety "I switched to this from Zoloft. I am doing so much better. The zoloft caused pretty severe side effects, but this has no side effects for me. My mood is better, my sleep is better. I am under the careful watch of a naturopath. This in combination with a B-complex (to help natural serotonin production) has made me a completely different person. Hallelujah!!"

10 / 10
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76 Report
  • nicola
  • July 26, 2017

For Anxiety "I started to feel its effects fully after about a week. At first I didn't think it helped with my mood much, that my mood had improved on its own. However, when I stopped taking it my mood dropped to how it had been before. I take 400mg in the evenings and feel calmer and sleepier. Haven't noticed any side effects. Give 5-HTP some time to work, at least a few days or maybe a week. It is a great alternative medicine, in my opinion."

9 / 10
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81 Report
  • Ton-toe
  • March 31, 2015

For Anxiety "I took this to try to counteract depression & anxiety. After the first dose I slept well and felt really good the next morning; I thought that, at long last, I had found an answer to my prayers. After the second dose my symptoms came back and were magnified many times. I felt so bad I worried I was going to need hospitalisation. It clearly works for some people, but for a few it produces extremely rapid and horrible effects."

1 / 10
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99 Report
  • Dizzie-
  • Taken for less than 1 month
  • February 26, 2016

For Anxiety "Don't take this with benzos, made me extra drowsy and anxious. One pill, I only took half of one pill (50mg!). I got some kind of adverse reaction. My insomnia got worse, I got panic attacks, shivering, tremor, felt disorientated and seriously more depressed. Now I have woken up in the middle of the night for many nights to same feeling: anxious, cant fall asleep again. I regret taking this. And I said once again: DONT MIX THIS WITH BENZOS and be careful if your nervous system is sensitive, you are sensitive to supplements or you suffer from bad insomnia cause it can cause paradoxical reaction. Start with tiny doses to find out, whether this is the right supplement to you. For me it definately is NOT. This supplement also has many side effects"

1 / 10
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89 Report
  • zeden
  • Taken for 1 to 6 months
  • September 28, 2015

For Anxiety "Just want to add this has been great. I was on citalopram but became too much of a problem for me having to go to the doctors every month and having work. Getting this delivered to my door was so much easier. Been taking 100mg every night before bed, its reduced my anxiety quite a bit. I'm still on a benzo for the time being but what people here have to understand this drug works with chemicals in you brain. This is the reason you get increased anxiety. When I started citalopram my anxiety went through the roof before improving my condition after about 8 weeks. Let it ride through and take it at night at first, it will increase your anxiety at first and may increase your depression in some people at first but afterwards it works wonders."

10 / 10
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92 Report
  • Cas
  • April 24, 2018

For Anxiety "Took 100mg about an hour and a half ago and I feel so comfortable like I the air is giving me a hug, almost like I am lightly stoned. his could be a total placebo effect, as it’s the first time taking it but I hope not. I’m also very content, nice long deep breaths, extremely calm. I look forward to the next couple of days/ weeks taking this and will keep you posted. I usually have social anxiety but couldn’t tell you if it has any effect on the severity of my anxiety as of yet as I’m in my home (I never get anxiety in my home) , will go to work and see... :)"

9 / 10
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70 Report
  • marti...
  • January 10, 2017

For Anxiety "DANGER!! DANGER!! Do your research before you take this drug. There is a potential contaminant that could lead to serious health conditions. I took this garbage for 1 month and my face swelled up and my breathing became restricted before I looked into it more and discovered the possibility of a condition called esonophilic mylagia which is correlated with improper production techniques. I stopped taking it but the side effects still linger."

1 / 10
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80 Report
  • Aldoyle
  • Taken for less than 1 month
  • March 1, 2017

For Anxiety "This stuff works great! For people that get sick or anything I'm just going to tell you, most likely you got serotonin syndrome from it because of too much of the chemical in your system and that is dangerous so be careful. I do note that it makes me sleep super well but the grogginess tends to linger around and I need a couple cups of coffee to cut through it. That being said I have that niarvana feeling of calmness and clarity. My mood and motivation is improved massively as well. I had especially hard times with waking up and getting started in anything that includes things I love doing and finishing things, after taking this it right away really sparked up my missing link. I will probably get st. Joins wort for tolerance breaks."

10 / 10
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74 Report
  • blue-...
  • Taken for less than 1 month
  • May 25, 2020

For Anxiety "Took a 50mg pill for the 2nd time. (1st time I took it, I felt weird but wasn't sure). This medicine actually increases my anxiety a lot and I feel very anxious and nervous. It also feels like my heart is racing. I do feel like I have a ton of energy but I didn't need energy, I needed to be less anxious. I will never take this again."

1 / 10
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47 Report
  • Snoopy
  • Taken for 1 to 6 months
  • June 1, 2015

For Anxiety "I'm taking 5-HTP with quite a few other supplements (all prescribed by a naturopathic doctor) so it's hard to say what is doing what but I added the 5-HTP after a week on the other supplements and it seemed to make a noticeable difference in my feeling of calm. I have been on every pharmaceutical AD out there plus benzodiazepines and I will tell you 5-HTP is different in a good way. If you have reached the end of the line with pharmaceuticals like I did it's worth giving supplements a try but I would recommend approaching it with a naturopathic doctor."

8 / 10
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83 Report
  • Summer
  • Taken for 1 to 6 months
  • May 10, 2020

For Anxiety "I have had great results using 5HTP for anxiety and panic. I have a couple different blends with the 5HTP, B6, L Theanine and one for night with melatonin they are both 50 mg and I usually only take 1/2. It tends to make me calm and tired so I prefer night dose but that night dose seems to keep me calm and in a much better mood all of the next day. I have had no side effects other than needing a nap after taking 100mg. It starts working quickly like 1/2 hour. I do find that after 2-3 weeks it tends to quit working so I take a week off then start again. I definitely recommend trying it. I have had a few bad experiences trying SSRI and I believe 5HTP actually works to increase seratonin."

9 / 10
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44 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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