5-HTP Side Effects

Generic Name: 5-hydroxytryptophan

Note: This page contains information about the side effects of 5-hydroxytryptophan. Some of the dosage forms included on this document may not apply to the brand name 5-HTP.

Not all side effects for 5-HTP may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

Applies to 5-hydroxytryptophan: oral capsule

Get emergency medical help if you have any of these signs of an allergic reaction while taking 5-hydroxytryptophan (the active ingredient contained in 5-HTP) hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your healthcare provider at once if you have a serious side effect such as skin rash, bruising, severe tingling, numbness, pain, or muscle weakness.

Less serious side effects of 5-hydroxytryptophan may include:

  • stomach pain;

  • nausea, vomiting;

  • gas, heartburn; or

  • loss of appetite.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

More about 5-HTP (5-hydroxytryptophan)

Consumer resources

Professional resources

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