Concerta

Generic Name: methylphenidate (oral) (METH il FEN i date)
Brand Names: Concerta, Metadate, Methylin, Ritalin

What is Concerta?

Concerta (methylphenidate) is a central nervous system stimulant. It affects chemicals in the brain and nerves that contribute to hyperactivity and impulse control.

Concerta is used to treat attention deficit disorder (ADD) and attention deficit hyperactivity disorder (ADHD). It is indicated for use in children 6 years of age and older, adolescents, and adults up to the age of 65. Concerta should be used as an integral part of a treatment program that includes psychological, educational, and social measures.

Concerta may also be used for other purposes not listed here.

Important information about Concerta

Do not use Concerta if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you use Concerta before the MAO inhibitor has cleared from your body. Do not use Concerta if you are allergic to methylphenidate or if you have glaucoma, overactive thyroid, severe high blood pressure, tics or Tourette's syndrome, angina, heart failure, heart rhythm disorder, recent heart attack, a hereditary condition such as fructose intolerance, glucose-galactose malabsorption, or sucrase-isomaltase deficiency, or severe anxiety, tension, or agitation.

Concerta may be habit-forming and should be used only by the person it was prescribed for. Never share Concerta with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.

Before taking Concerta

Do not take Concerta if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you use Concerta before the MAO inhibitor has cleared from your body.

Do not use Concerta if you are allergic to methylphenidate or if you have:

• glaucoma;

• overactive thyroid;

• severe high blood pressure;

• angina (chest pain), heart failure, heart rhythm disorder, or recent heart attack;

• a personal or family history of tics (muscle twitches) or Tourette's syndrome;

• severe anxiety, tension, or agitation (methylphenidate can make these symptoms worse); or

• a hereditary condition such as fructose intolerance, glucose-galactose malabsorption, or sucrase-isomaltase insufficiency.

Some stimulants have caused sudden death in children and adolescents with serious heart problems or congenital heart defects. Tell your doctor if you have a congenital heart defect.

If you have any of these other conditions, your doctor may need to adjust your Concerta dose or order special tests:

• a congenital heart defect;

• a personal or family history of mental illness, psychotic disorder, bipolar illness, depression, or suicide attempt;

• epilepsy or other seizure disorder; or

• a history of drug or alcohol addiction.

FDA pregnancy category C. It is not known whether Concerta will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether methylphenidate passes into breast milk or if it could harm a nursing baby. Do not use Concerta without telling your doctor if you are breast-feeding a baby.

See also: Concerta pregnancy and breastfeeding warnings (in more detail)

Long-term use of Concerta can slow a child's growth. Tell your doctor if the child using this medication is not growing or gaining weight properly.

Do not give Concerta to a child younger than 6 years old without the advice of a doctor.

How should I take Concerta?

Take Concerta exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Concerta can be taken with or without food.

Do not crush, chew, or break an extended-release Concerta tablet. Swallow it whole. Breaking the pill may cause too much of the drug to be released at one time.

To prevent sleep problems, take Concerta early in the day, no later than 6:00 pm.

If you need to have any type of surgery, tell the surgeon ahead of time that you are using Concerta. You may need to stop using the medicine the day of your surgery.

Store Concerta at room temperature away from moisture and heat. Keep track of the amount of medicine used from each new bottle. Methylphenidate is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

See also: Concerta dosage (in more detail)

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is later than 6:00 p.m. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of Concerta can be fatal.

Overdose can cause vomiting, agitation, tremors, muscle twitching, seizure (convulsions), confusion, hallucinations, sweating, fast or pounding heartbeat, blurred vision, dry mouth and nose, and fainting.

What should I avoid while taking Concerta?

Concerta may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Concerta side effects

Get emergency medical help if you have any of these signs of an allergic reaction to Concerta: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop taking Concerta and call your doctor at once if you have a serious side effect such as:

• fast, pounding, or uneven heartbeats;

• feeling like you might pass out;

• fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;

• aggression, restlessness, hallucinations, unusual behavior, or motor tics (muscle twitches);

• easy bruising, purple spots on your skin; or

• dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure).

Less serious Concerta side effects may include:

• stomach pain, nausea, vomiting, loss of appetite;

• vision problems, dizziness, mild headache;

• sweating, mild skin rash;

• numbness, tingling, or cold feeling in your hands or feet;

• nervous feeling, sleep problems (insomnia); or

• weight loss.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Concerta side effects (in more detail)

What other drugs will affect Concerta?

Tell your doctor about all other medicines you use, especially:

• a blood thinner such as warfarin (Coumadin);

• clonidine (Catapres);

• dobutamine (Dobutrex), epinephrine (EpiPen), or isoproterenol (Isuprel);

• cold/allergy medicine that contains phenylephrine (a decongestant);

• potassium citrate (Urocit-K, Twin-K), sodium acetate, sodium bicarbonate (Alka-Seltzer), citric acid and potassium citrate (Cytra-K, Poly-Citra), or sodium citrate and citric acid (Bicitra, Oracit);

• medications to treat high or low blood pressure;

• stimulant medications or diet pills;

• seizure medicine such as phenytoin (Dilantin), phenobarbital (Luminal), primidone (Mysoline); or

• an antidepressant such as amitriptyline (Elavil, Vanatrip), citalopram (Celexa), doxepin (Sinequan), fluoxetine (Prozac, Sarafem), nortriptyline (Pamelor) paroxetine (Paxil), sertraline (Zoloft), and others.

This list is not complete and other drugs may interact with Concerta. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about Concerta.

• Every effort has been made to ensure that the information provided is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects.

Copyright 1996-2010 Cerner Multum, Inc. Version: 11.01. Revision Date: 07/07/2010 4:26:01 PM.