Adderall XR

Pronunciation

Generic Name: amphetamine and dextroamphetamine (am FET a meen and DEX troe am FET a meen)
Brand Name: Adderall, Adderall XR

What is Adderall XR (amphetamine and dextroamphetamine)?

Amphetamine and dextroamphetamine are central nervous system stimulants that affect chemicals in the brain and nerves that contribute to hyperactivity and impulse control.

Amphetamine and dextroamphetamine is a combination medicine used to treat narcolepsy and attention deficit hyperactivity disorder (ADHD).

Amphetamine and dextroamphetamine may also be used for purposes not listed in this medication guide.

What is the most important information I should know about Adderall XR (amphetamine and dextroamphetamine)?

You should not use this medication if you have glaucoma, severe anxiety or agitation, or a personal or family history of tics (muscle twitches) or Tourette's syndrome.

Do not use this medicine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

Slideshow: Does Your Child Have ADHD? Recognizing Signs & Treatment Options

Amphetamine and dextroamphetamine may be habit forming. Never share this medicine with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it. Using this medication improperly can cause death or serious side effects on the heart.

What should I discuss with my doctor before taking Adderall XR (amphetamine and dextroamphetamine)?

Do not use this medicine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

You should not use amphetamine and dextroamphetamine if you are allergic to amphetamine or dextroamphetamine or if you have:

  • glaucoma;

  • severe anxiety, tension, or agitation; or

  • a personal or family history of tics (muscle twitches) or Tourette's syndrome.

Some stimulants have caused sudden death in people with serious heart problems or congenital heart defects. Tell your doctor if you have:

  • heart disease, heart rhythm disorder;

  • coronary artery disease (hardened arteries); or

  • history of heart attack.

To make sure this medicine is safe for you, tell your doctor if you have:

  • high blood pressure;

  • a history of mental illness or psychosis;

  • peripheral vascular disease such as Raynaud's syndrome;

  • epilepsy or other seizure disorder; or

  • if you have a history of drug or alcohol addiction.

Amphetamine and dextroamphetamine may be habit forming. Never share this medicine with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.

FDA pregnancy category C. It is not known whether this medication will harm an unborn baby. Amphetamine and dextroamphetamine could cause premature birth, low birth weight, or withdrawal symptoms in a newborn if the mother takes the medicine during pregnancy. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

Amphetamine and dextroamphetamine can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are using this medication.

Long-term use of amphetamine and dextroamphetamine can slow a child's growth. Tell your doctor if the child using this medication is not growing or gaining weight properly.

How should I take Adderall XR (amphetamine and dextroamphetamine)?

Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Do not crush, chew, break, or open an extended-release capsule. Swallow it whole.

Your doctor will need to check your progress while you are using amphetamine and dextroamphetamine.

This medication can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using amphetamine and dextroamphetamine.

Store at room temperature away from moisture, heat, and light.

Keep track of the amount of medicine used from each new bottle. Amphetamine and dextroamphetamine is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription. Using this medication improperly can cause death or serious side effects on the heart.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of amphetamine and dextroamphetamine can be fatal.

What should I avoid while taking Adderall XR (amphetamine and dextroamphetamine)?

This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Do not take amphetamine and dextroamphetamine late in the day. A dose taken too late in the day can cause sleep problems (insomnia).

Avoid drinking fruit juices or taking vitamin C at the same time you take amphetamine and dextroamphetamine. These can make your body absorb less of the medicine.

Adderall XR (amphetamine and dextroamphetamine) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have:

  • fast, pounding, or uneven heartbeats;

  • pain or burning when you urinate;

  • talking more than usual, feelings of extreme happiness or sadness;

  • numbness, tingling, or strange sensations under your skin;

  • numbness, pain, cold feeling, unexplained wounds, or skin color changes (pale, red, or blue appearance) in your fingers or toes;

  • tremors, hallucinations, unusual behavior, or motor tics (muscle twitches);

  • penis erection that is painful or lasts 4 hours or longer (rare); or

  • dangerously high blood pressure (severe headache, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure).

Common side effects may include:

  • nausea, loss of appetite, stomach pain;

  • dry mouth;

  • anxiety, agitation, mood changes, feeling nervous;

  • sleep problems (insomnia); or

  • headache, weakness, dizziness.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect Adderall XR (amphetamine and dextroamphetamine)?

Ask your doctor before using an antacid or other stomach acid reducer (Nexium, Pepcid, Prevacid, Prilosec, Protonix, Tagamet, Zantac, and others). Some of these medicines can change the way your body absorbs amphetamine and dextroamphetamine, and may increase side effects.

Other drugs may interact with amphetamine and dextroamphetamine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Where can I get more information?

  • Your pharmacist can provide more information about amphetamine and dextroamphetamine.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2012 Cerner Multum, Inc. Version: 9.01. Revision Date: 2014-01-13, 2:29:00 PM.

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