Generic Name: tolterodine (tol-TER-oh-deen)
Brand Name: Detrol
Tolterodine is used for:
Treating overactive bladder with symptoms of urinary frequency, urgency, and leakage. It may also be used for other conditions as determined by your doctor.
Tolterodine is an antimuscarinic (anticholinergic) agent. It works by blocking a chemical that causes contractions of the bladder.
Do NOT use tolterodine if:
- you are allergic to any ingredient in tolterodine or to fesoterodine
- you have uncontrolled narrow-angle glaucoma, trouble urinating, or have slowed emptying of your stomach
- you are taking a solid oral potassium product (eg, tablet)
Contact your doctor or health care provider right away if any of these apply to you.
Before using tolterodine:
Some medical conditions may interact with tolterodine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have glaucoma; a blockage of the bladder, stomach, or bowel; stomach or bowel problems (eg, slowed moving of the bowel, constipation); spinal cord injury; dementia; liver or kidney problems; or myasthenia gravis (muscle weakness)
- if you or a family member have a history of irregular heartbeat (eg, prolonged QT, long QT syndrome)
Some MEDICINES MAY INTERACT with tolterodine. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Antiarrhythmics (eg, amiodarone, quinidine) because the risk of irregular heartbeat may be increased
- Solid oral potassium products (eg, tablets) because the risk of stomach or bowel irritation may be increased by tolterodine
- Other anticholinergics (eg, scopolamine), azole antifungals (eg, itraconazole, ketoconazole, miconazole), cyclosporine, HIV protease inhibitors (eg, ritonavir), macrolide antibiotics (eg, clarithromycin, erythromycin), nefazodone, or vinblastine because they may increase the risk of tolterodine's side effects
This may not be a complete list of all interactions that may occur. Ask your health care provider if tolterodine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use tolterodine:
Use tolterodine as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- An extra patient leaflet is available with tolterodine. Talk to your pharmacist if you have questions about this information.
- Take tolterodine by mouth with or without food.
- Tolterodine works best if it is taken at the same time each day.
- If you miss a dose of tolterodine, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use tolterodine.
Important safety information:
- Tolterodine may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use tolterodine with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Do NOT change your dose of tolterodine without checking with your doctor.
- Tolterodine should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
- Caution is advised when using tolterodine in CHILDREN; they may be more sensitive to its effects, especially an increased risk of urinary tract infection or behavior or attention problems.
- PREGNANCY and BREAST-FEEDING: If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using tolterodine while you are pregnant. It is not known if tolterodine is found in breast milk. Do not breast-feed while taking tolterodine.
Possible side effects of tolterodine:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Blurred vision; constipation; dizziness; drowsiness; dry eyes; dry mouth; headache; indigestion; stomach pain.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, throat, or tongue; unusual hoarseness); chest pain; confusion; difficult or painful urination; disorientation; fainting; fast or irregular heartbeat; hallucinations; memory problems; severe dizziness; swelling of the hands, ankles, or feet.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include difficulty breathing; difficulty urinating; dilated pupils; dry mouth; excitation; fast heartbeat; hallucinations; seizures.Proper storage of tolterodine:
Store tolterodine at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep tolterodine out of the reach of children and away from pets.
- If you have any questions about tolterodine, please talk with your doctor, pharmacist, or other health care provider.
- Tolterodine is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take tolterodine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about tolterodine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to tolterodine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using tolterodine.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.