VibrinThis page contains information on Vibrin for veterinary use.
The information provided typically includes the following:
- Vibrin Indications
- Warnings and cautions for Vibrin
- Direction and dosage information for Vibrin
VibrinThis treatment applies to the following species:
Campylobacter Fetus Bacterin
U.S. Vet. Lic. No.: 190
VIBRIN® is prepared from an inactivated, concentrated suspension of Campylobacter fetus, bovine isolate, in a patented repository base.1
VIBRIN® is for vaccination of healthy cows and heifers as an aid in preventing campylobacteriosis (vibriosis) caused by Campylobacter fetus.
Directions For Use
1. General Directions: Vaccination of healthy cows and heifers is recommended. Shake well. Aseptically administer 2 mL subcutaneously in the upper part of the neck. In accordance with Beef Quality Assurance guidelines, this product should be administered subcutaneously (SC) under the skin.
2. Primary Vaccination: Administer a single 2-mL dose to all breeding cows and heifers between 30 days and 7 months before breeding. Pregnant animals can be safely vaccinated.2,4
3. Revaccination: Annual revaccination with a single dose is recommended between 30 days and 7 months before breeding.
4. Good animal husbandry and herd health management practices should be employed.
Precaution(s): Store at 2°-7°C. Prolonged exposure to higher temperatures may adversely affect potency. Do not freeze.
Use entire contents when first opened.
Sterilized syringes and needles should be used to administer this vaccine.
Caution(s): As with many vaccines, anaphylaxis may occur after use. Initial antidote of epinephrine is recommended and should be followed with appropriate supportive therapy.
This product has been shown to be efficacious in healthy animals. A protective immune response may not be elicited if animals are incubating an infectious disease, are malnourished or parasitized, are stressed due to shipment or environmental conditions, are otherwise immunocompromised, or the vaccine is not administered in accordance with label directions.
Warning(s): To avoid vaccination site trim-out, do not vaccinate within 60 days before slaughter.
For veterinary use only.
Discussion: Disease Description: Campylobacteriosis is a venereal disease of cattle transmitted during breeding, either through coitus or artificial insemination with contaminated semen. Although the disease is often subclinical, in cows it causes temporary infertility, irregular estrus cycles, delayed conception, and occasionally, abortion.
Trial Data: Safety and Efficacy: Chemical inactivation renders VIBRIN® incapable of causing or spreading infectious disease. The special adjuvant base enhances and prolongs antigenic stimulation and may produce a localized vaccine granuloma. These are noninflammatory, however, and usually disappear in several weeks. Field use and extensive, controlled tests in breeding cattle under experimental conditions demonstrated that the serotype of Campylobacter fetus used in VIBRIN® was effective in prevention of campylobacteriosis.2,3 Pregnancy rates in vaccinated heifers were up to 44% higher than in nonvaccinated control heifers. All research conducted on VIBRIN® indicated a single dose is effective and there is no advantage in using 2 injections.2,4,5
ReferencesAvailable upon request.
Presentation: 10 dose and 50 dose vials.
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