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Tylosin 100 (Canada)

This treatment applies to the following species:
Company: Bio Agri Mix

Tylosin Granular USP

FOR VETERINARY USE ONLY

Antibiotic

DIN 02472058

FOR USE IN SWINE, BEEF CATTLE AND BROILER CHICKEN FEEDS ONLY

Active Ingredient

tylosin (as tylosin phosphate)

220 g per kilogram of premix

Tylosin 100 Indications

A. Swine

I. For use as an aid in the treatment and the prevention of cyclic recurrence of swine dysentery (bloody scours, bloody diarrhea, black scours, hemorrhagic colitis, vibrio).

II. For use as an aid in the prevention of porcine proliferative enteropathy (PPE) or ileitis associated with Lawsonia intracellularis.

III. As an aid in the treatment of porcine proliferative enteropathy (PPE) or ileitis associated with Lawsonia intracellularis when used following treatment with TYLOSIN Soluble Powder.

IV. For the treatment of porcine proliferative enteropathy (PPE) or ileitis associated with Lawsonia intracellularis.

V. For the treatment of porcine proliferative enteropathy (PPE) or ileitis associated with Lawsonia intracellularis in the presence of persistent or recurring infection.

B. Beef Cattle

To reduce the incidence of liver abscesses caused by Trueperella pyogenes (formerly Arcanobacterium pyogenes) and Fusobacterium necrophorum in beef cattle (steers and heifers) fed in confinement for slaughter.

C. Broiler Chickens

As an aid in the treatment of necrotic enteritis caused by Clostridium perfringens in broiler chickens.

Dosage and Administration

To reduce the development of antimicrobial resistance and maintain effectiveness, use this antibiotic prudently and for the shortest duration required to achieve the desired clinical outcome.

IMPORTANT: Must be thoroughly mixed in feeds before use.

Mixing Directions For Swine

Tylosin 100 Indication I: for Treatment

Concurrent with TYLOSIN Soluble Powder treatment of the disease, administer TYLOSIN 100 at the rate of 500 g (110 g tylosin) per 1000 kg of complete feed for three (3) weeks. The medicated drinking water, containing one gram of tylosin tartrate per U.S. gallon (3.785 litres) should be provided for the first three (3) days of treatment, or until symptoms disappear.

Tylosin 100 Indication I: For Prevention Following Treatment

To prevent recurrence of swine dysentery, the level of premix should be reduced to 200 g (44 g tylosin) per 1000 kg of complete feed until market weight. Feed as the sole ration.

Indication II: Administer TYLOSIN 100 at a rate of 500 g (110 g tylosin) per 1000 kg of complete feed. Feed as the sole ration for 21 days, commencing prior to an anticipated outbreak of disease.

Tylosin 100 Indication Iii: For Treatment Following Tylosin Soluble Powder

As an aid in the treatment of porcine proliferative enteropathy (PPE) or ileitis associated with Lawsonia intracellularis, treat by way of drinking water with Tylosin Soluble Powder for 7 days at 1 gram per 12 litres (83 mg per litre) followed by TYLOSIN 100 in the feed at a rate of 500 g (110 g tylosin) per 1000 kg of complete feed for 7 days.

Tylosin 100 Indication Iv: For Treatment

To treat porcine proliferative enteropathy (PPE) or ileitis associated with Lawsonia intracellularis, administer TYLOSIN 100 at a rate of 500 g (110 g tylosin) per 1000 kg of complete feed for 3 weeks.

Tylosin 100 Indication V: For Treatment In The Presence Of Persistent Or Recurring Infection

To treat porcine proliferative enteropathy (PPE) or ileitis associated with Lawsonia intracellularis in the presence of persistent or recurring infection, administer TYLOSIN 100 at a rate of 500 g (110 g tylosin) per 1000 kg of complete feed for 3 weeks. Follow with TYLOSIN 100 at a rate of 200 g (44 g tylosin) per 1000 kg of complete feed for 3 weeks.

Mixing Directions For Beef Cattle

Administer TYLOSIN 100 at the rate of 50 g (11 g tylosin) per 1000 kg of complete diet including roughage (100% dry matter basis). Feed continuously as the sole ration.

NOTE: Not for use in thixotropic liquid supplements.

Mixing Directions For Broiler Chickens

Administer TYLOSIN 100 at a rate of 910 g (200 g tylosin) per 1000 kg of complete feed for the treatment of necrotic enteritis in broiler chickens. Feed as the sole ration for 7 days.

CAUTIONS:

1. Do not use in replacement, breeding, or lactating cattle.

2. Not to be used in feeds containing pellet binding agents with the exception of Lignosol (4%) and Agri-Colloid (0.3%). Do not use in any supplement, concentrate or complete feed containing bentonite. Not for use in thixotropic liquid supplements.

3. When treating swine dysentery or necrotic enteritis, the diagnosis should be re-determined in cases of lack of response within 3 to 5 days of treatment commencement.

4. When treating porcine proliferative enteropathy (PPE) or ileitis, the diagnosis should be re-evaluated when results are not satisfactory.

Warnings

1. Swine treated concurrently with this drug in complete feed and with tylosin tartrate in drinking water must not be slaughtered for use in food for at least 48 hours after the latest treatment with tylosin in drinking water.

2. No withdrawal period is required when swine are treated with this drug at a level of 110 grams of tylosin per 1000 kg of complete feed.

3. No withdrawal period is required for beef cattle and broiler chickens when treated according to the label.

4. Do not use in laying hens.

5. This product may be irritating to human skin and mucous membranes. When mixing and handling TYLOSIN 100, avoid inhalation, oral exposure and direct contact with skin or eyes. Use protective clothing, impervious gloves, and a dust mask.

6. Keep out of reach of children.

Adverse Reactions

In rare cases, edema of the rectal mucosa and mild anal protrusion with pruritis, erythema and diarrhea have been reported in pigs consuming this drug in feed.

Storage

Store in a cool dry place below 30°C.

PRESENTATION:

TYLOSIN 100 is supplied in a 25 kg multi-wall paper bag.

NET WEIGHT: 25 kg

MANUFACTURED AND DISTRIBUTED BY:

Bio Agri Mix LP, PO Box 399, Mitchell, ON, N0K 1N0

CONTAINS ANTIMICROBIAL

USE RESPONSIBLY

MADE IN CANADA

DATE

1652-00, SEP/17

CPN: 1161055.1

BIO AGRI MIX LP
P.O. BOX 399, 11 ELLENS STREET, MITCHELL, ON, N0K 1N0
Telephone:   519-348-9865
Order Desk:   800-265-1763
Technical Information:   226-303-2503
Fax:   519-348-4100
Website:   www.bioagrimix.com
Email:   info@bioagrimix.com
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