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Tetanus Antitoxin, Equine Origin

This page contains information on Tetanus Antitoxin, Equine Origin for veterinary use.
The information provided typically includes the following:
  • Tetanus Antitoxin, Equine Origin Indications
  • Warnings and cautions for Tetanus Antitoxin, Equine Origin
  • Direction and dosage information for Tetanus Antitoxin, Equine Origin

Tetanus Antitoxin, Equine Origin

This treatment applies to the following species:
Company: Colorado Serum

Tetanus antitoxin is prepared from the blood of healthy horses that have been specifically hyperimmunized. It is recommended for use as an aid in the prevention and treatment of tetanus in animals.

Tetanus is caused by a neurotoxin (poison) produced by the growth of Clostridium tetani, an anaerobic microorganism, in necrotic tissue.

Tetanus Antitoxin is recommended for use when a non-immunized animal suffers a deep wound that may have been contaminated with soil, following castration or docking, and other situations where tetanus infection has been a problem.

This product was licensed prior to the requirement to establish a minimum age for use. The exact duration of passive immunity is unknown but literature states 7-14 days. Safety in pregnant animals is unknown.

Directions For Use

Do not vaccinate within 21 days before slaughter. Shake well before use. Use entire contents when first opened. Store at 2°-8° C. Do not freeze. Do not mix with other products.

DOSAGE & ADMINISTRATION: 1500 units administered subcutaneously or intramuscularly is the recommended preventive dose.

5 ml equals 1500 units.

Large doses of Tetanus Antitoxin may provide a beneficial response in animals already infected with tetanus, but success of treatment is not assured. For treatment, administer 10,000 to 50,000 units to horses and cattle, 3,000 to 15,000 units to sheep and swine.

Animals suffering slow healing puncture wounds or deep abrasions should be given a second dose of antitoxin in 7 days and additionally as considered necessary. Consult a veterinarian for vaccination program.

Vaccination with tetanus toxoid is recommend for healthy domestic animals not infected with tetanus to establish an active immunity for prevention against disease.


Anaphylactoid reaction may occur following administration of products of this nature. If noted, administer adrenalin or equivalent.

The use of equine serum has been associated with hepatitis (Theiler’s Disease). If user has questions, consult a veterinarian.

In case of human exposure, consult a physician.

Contains phenol and thimerosal as preservatives.

Conveniently packaged in 1,500 and 15,000 unit vials, and packages containing 10 x 1,500 unit vials.


VLN: 188 / PCN: 6302.00

COLORADO SERUM COMPANY, 4950 York Street, Denver, Colorado 80216





Order #

1 dose (5 ml)

1,500 units


10 - 1 dose (5 ml) vials

10 - 1,500 units


10 dose (50 ml)

15,000 units


CPN: 1101032.3

4950 YORK STREET, P.O. BOX 16428, DENVER, CO, 80216-0428
Telephone:   303-295-7527
Order Desk:   800-525-2065
Fax:   303-295-1923
Every effort has been made to ensure the accuracy of the Tetanus Antitoxin, Equine Origin information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert.

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