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Ovine Ecthyma Vaccine

This page contains information on Ovine Ecthyma Vaccine for veterinary use.
The information provided typically includes the following:
  • Ovine Ecthyma Vaccine Indications
  • Warnings and cautions for Ovine Ecthyma Vaccine
  • Direction and dosage information for Ovine Ecthyma Vaccine

Ovine Ecthyma Vaccine

This treatment applies to the following species:
Company: Colorado Serum

Live Virus

GENERAL INFORMATION: This product has been shown to be effective for the vaccination of healthy sheep and goats against contagious Ecthyma (Sore Mouth Disease). This product was licensed prior to the requirement to establish a minimum age for use. The duration of immunity is unknown. For information regarding efficacy and safety data, see

Ovine Ecthyma (Sore Mouth) is a contagious disease of sheep and goats caused by a virus. It is characterized by vesicular, pustular lesions that progress to the formation of thick scabs on the lips or the skin.

Infected sucklings may transmit the infection to the udder of susceptible ewes, which limits nursing, leading to severe economic impact from loss of weight and condition. Spontaneous healing in 4-5 weeks may occur without treatment; however, if secondary bacterial infection develops, fatalities can range from 10-50 percent.

Treatment is difficult. In small flocks, scabs can be removed and the lesions cleansed. A penetrating antiseptic may be of limited value regarding bacterial infections; however, preventative vaccination is the best procedure.

WHEN TO VACCINATE: Because dried scabs retain the infective virus which is resistant to heat and cold and can survive from year to year, vaccinating new lambs and kids is advisable. Range lambs moving into feedlots should be vaccinated at least 14 days before shipment to prevent possible spread of virus after arrival.

DOSAGE & ADMINISTRATION: The recommended single dose for both sheep and goats is one drop of vaccine, approximately 0.04 ml. There are 100 doses per bottle of vaccine, approx. 0.04 ml per dose (one drop). Rehydrate vaccine with accompanying diluent immediately before use. Shake well until completely dissolved.

Select a wool free area of skin such as inside the flank and scarify the outer layer by scratching with the notched handle of the applicator furnished as a part of the package. Scratching should not be deep enough to cause bleeding but should be sufficient to roughen the skin. Scarified area should be at least one square inch. The brush end of the applicator should be dipped into the bottle and the vaccine then vigorously brushed into the prepared scarified area.

Reddening and a slight swelling of the site of administration should be observed a few days after vaccination. The area will raise, rupture, and scab over representing a “take”, indicating a successful vaccination. Scabs will dry and fall off in about 2 to 4 weeks.

Historically, annual revaccination is recommended. Contact veterinarian for advice.


Brushes and scarifiers should be used only in a single flock of sheep. If the scarifier/applicator is needed a second time, it should be sterilized by boiling in water for several minutes. Do not use disinfectants to sterilize equipment. In the event of human exposure, contact a physician. Safety in pregnant animals is unknown.

OTHER INFORMATION: Do not vaccinate within 21 days before slaughter or within 24 hours of dipping or spraying. Store at 2-8° C. Use entire contents when first opened. Do not freeze. Do not mix with other products other than enclosed diluent. Inactivate unused contents before disposal.

Contains Penicillin G and Streptomycin Sulfate as preservatives. Packaged in 100 dose size.



VLN: 188 / PCN: 1821.00

COLORADO SERUM COMPANY, 4950 York Street, Denver, Colorado 80216


100 doses

Rehydrate with accompanying diluent (5 ml)

CPN: 1101027.1

4950 YORK STREET, P.O. BOX 16428, DENVER, CO, 80216-0428
Telephone:   303-295-7527
Order Desk:   800-525-2065
Fax:   303-295-1923
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