Neosol Soluble Powder

Neomycin Sulfate

Antibacterial

CAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Restricted Drug - Use Only as Directed (California)

For Oral Use in Animals Only

ANADA #200-235, APPROVED BY FDA

For the treatment and control of colibacillosis (bacterial enteritis) caused by Escherichia coli susceptible to neomycin sulfate in cattle (excluding veal calves), swine, sheep and goats.

Add to drinking water - Not for use in liquid supplements.

3.5 oz (100 Gram) Packet:

Each packet contains: 71.5 gm neomycin sulfate equivalent to 50 gm neomycin.

Neosol Soluble Powder Dosage And Administration

Administer to cattle (excluding veal calves), swine, sheep and goats at a dose of 10 mg neomycin sulfate per pound of body weight per day in divided doses for a maximum of 14 days:

Herd Treatment: Each packet will treat 7150 pounds body weight. Therefore, estimate the total number of pounds of body weight of the animals to be treated and administer one (1) packet (or portion thereof) for each 7150 pounds. The product should be added to the amount of drinking water estimated to be consumed in 12 - 24 hours. Provide medicated water as the sole source of water each day until consumed, followed by non-medicated water as required. Fresh medicated water should be prepared each day.

Individual Animal Treatment: To provide 10 mg neomycin sulfate per pound of body weight, mix one (1) level teaspoon in water or milk for each 160 pounds body weight. Administer daily either as a drench in divided doses or in the drinking water to be consumed in 12 - 24 hours.

Drinking Water: Swine - Use the number of packets indicated below in 256 gallons of water, or in two gallons of stock solution used in proportioner set to meter one ounce per gallon.

50 lb. (22.6 kg) Drum:

Contains per pound: 325 gm neomycin sulfate equivalent to 227.5 gm neomycin.

Neosol Soluble Powder Dosage And Administration

Administer 10 mg neomycin sulfate per pound of body weight per day in divided doses for a maximum of 14 days. Using measuring spoons, the recommended dosage can be determined as follows:

Daily Schedule for Drinking Water

*Level Tablespoonful - US Standard Measure

The product should be added to the amount of drinking water estimated to be consumed in 12 - 24 hours. Provide medicated water as the sole source of water each day until consumed, followed by non-medicated water as required. Fresh medicated water should be prepared each day. For a stock solution, add six level tablespoonfuls to one gallon of water. Each pint of this stock solution will medicate 5 gallons of drinking water. For use in Automatic Proportioners delivering 2 ounces of stock solution per gallon of drinking water, dissolve 9 level tablespoonfuls in a gallon of water to make the stock solution.

Individual Animal Treatment - To provide 10 mg neomycin sulfate per pound of body weight, mix one (1) level teaspoon in water or milk for each 160 pounds of body weight. Administer daily either as a drench in divided doses or in the drinking water to be consumed in 12 - 24 hours.

3.5 oz (100 Gram) Packet and 50 lb. (22.6 kg) Drum:

Neosol Soluble Powder Caution

To administer the stated dosage, the concentration of neomycin required in medicated water must be adjusted to compensate for variation in age and weight of animal, the nature and severity of disease signs, and environmental temperature and humidity, each of which affects water consumption. If symptoms persist after using this preparation for 2 or 3 days, consult a veterinarian. If symptoms such as fever, depression, or going off feed develop, oral neomycin is not indicated as the sole treatment since systemic levels of neomycin are not obtained due to low absorption from the gastrointestinal tract.

Important: Treatment should continue 24 to 48 hours beyond remission of disease symptoms, but not to exceed a total of 14 consecutive days. Animals not drinking or eating should be treated individually by drench.

Warning Not for human use. Keep out of reach of children. Discontinue treatment prior to slaughter by at least the number of days listed below for appropriate species. Cattle 1 day Swine and goats 3 days Sheep 2 days A withdrawal period has not been established for this product in pre-rumination calves. Do not use in calves to be processed for veal. A milk discard period has not been established for this product in lactating dairy cattle. Do not use in female dairy cattle 20 months of age or older. Use of more than one product containing neomycin or failure to follow withdrawal times may result in illegal drug residues.

Important: Store in a dry place. When storing partially used containers, securely close bags to prevent contents from caking.

KEEP CONTAINER TIGHTLY CLOSED

STORE AT ROOM TEMPERATURE

MED-PHARMEX INC., Pomona, CA 91767

CPN: 1027009.1