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M-Eloxyn (Canada)

This page contains information on M-Eloxyn for veterinary use.
The information provided typically includes the following:
  • M-Eloxyn Indications
  • Warnings and cautions for M-Eloxyn
  • Direction and dosage information for M-Eloxyn


This treatment applies to the following species:
Company: Zoetis

Meloxicam 1.5 mg/mL Oral Suspension for Dogs

Veterinary Use Only

DIN 02406403


Each mL contains 1.5 mg of meloxicam in a yellowish suspension with an odour of honey. Meloxicam acts by inhibition of prostaglandin synthesis.

Therapeutic classification: M-Eloxyn 1.5 mg/mL oral suspension for dogs is a nonsteroidal anti-inflammatory drug (NSAID) of the oxicam group.

M-Eloxyn Indications

M-Eloxyn 1.5 mg/mL oral suspension for dogs is indicated in dogs only, for the alleviation of inflammation and pain in both acute and chronic musculo-skeletal disorders.

Dosage and Administration

M-Eloxyn 1.5 mg/mL oral suspension for dogs should be administered mixed with food. On the first day of treatment, a single dose of 0.2 mg meloxicam/kg body weight should be given. Treatment is to be continued once daily by oral administration (at 24-hour intervals) at a maintenance dose of 0.1 mg meloxicam/kg body weight.

Particular care should be given with regard to the accuracy of dosing. The suspension can be given using the measuring syringe provided in the package (see below). The syringe has a kg-body weight scale which corresponds to the volume required for the maintenance dose (i.e., 0.1 mg Meloxicam per kg body weight). Twice the volume should be administered on the first day as the initial dose.

The following dosing table indicates what volume to administer depending on the weight of the dog:


Maintenance Dosage

7.5 kg

0.5 mL

15 kg

1 mL

22.5 kg

1.5 mL

30 kg

2 mL

37.5 kg

2.5 mL

45 kg

3 mL

52.5 kg

3.5 mL

60 kg

4 mL

Shake well before use. Please follow carefully the instructions of the veterinarian.

Dosing Procedure using the measuring syringe:

Please follow these steps:

Step 1. Before using M-Eloxyn 1.5 mg/mL oral suspension for dogs for the very first time ensure that you have the bottle, circular plastic insert and syringe.

Step 2. Place the circular plastic insert into the neck of the bottle and push down until securely in place. Once in place the insert will not need to be removed.

Step 3.

Replace the cap onto the bottle and shake it well. Take off the bottle cap and attach the dosing syringe to the bottle by gently pushing the end into the hole.

Step 4.

Turn the bottle with the syringe in place upside down and slowly withdraw the plunger until the required dose is evident.

Step 5. Turn the bottle/syringe the right way up and with a twisting movement separate the syringe from the bottle.

Step 6. Push the plunger until all contents of the syringe have been dispensed onto the food.

A clinical response is normally seen within 3 to 4 days. Treatment should be discontinued after 10 days at the latest if no clinical improvement is apparent.


M-Eloxyn 1.5 mg/mL oral suspension for dogs should not be administered if gastric or intestinal ulceration or bleeding is suspected; if there is evidence of cardiac, hepatic or renal disease; or if there is evidence of a haemorrhagic disorder or individual hypersensitivity to the product. Do not administer concurrently, other steroidal or nonsteroidal anti-inflammatory drugs (NSAIDs), aminoglycoside antibiotics or anti-coagulant agents. Pre-treatment with other steroidal or nonsteroidal anti-inflammatory drugs (NSAIDS) may result in additional or increased effects. Depending on the pharmacokinetic properties of the products used previously, an appropriate treatment-free period with such drugs should be observed before commencement of treatment.

M-Eloxyn Caution

Not approved for use in cats. M-Eloxyn 1.5 mg/mL oral suspension for dogs should not be administered to breeding, pregnant or lactating dogs. Do not exceed the stated dose. In case of overdosing, symptomatic treatment should be initiated.

Animals being treated with meloxicam should be monitored for the occurrence of side effects as susceptibility varies with the individual.

If gastrointestinal or other adverse reactions occur, treatment should be discontinued.

As for all NSAIDs, use in debilitated aged animals may involve additional risk. If use in such animals cannot be avoided, a reduced dosage and careful clinical management may be required. Safety of meloxicam in very young puppies has not been evaluated.


Adverse Reactions

Typical adverse reactions of NSAIDs such as loss of appetite, vomiting, diarrhea, apathy and renal failure have occasionally been reported. These adverse reactions are in most cases transient and disappear following termination of the treatment but in very rare cases may be serious or fatal.

Although all adverse reactions are not reported, the following adverse reaction information is based on voluntary reporting by veterinarians and pet owners/caregivers. It should be noted that suspected adverse reactions listed here reflect reporting, not causality. The categories of adverse reactions are listed in decreasing order of frequency by body system. In rare cases, death has been associated with some of these adverse reactions:

Digestive tract: vomiting, diarrhea, melena, hematemesis, gastric ulcer.

Systemic: anorexia, lethargy, jaundice.

Renal and urinary: elevated creatinine, elevated BUN, acute renal failure.

Neurological: ataxia, seizure, sleepiness, trembling.

Behavioural: behavioural disorder, hyperactivity.

Skin and appendages: pruritus, eczema, alopecia local, moist dermatitis.

Immune system: urticaria, allergic dermatitis, immune mediated hemolytic anemia, immune mediated thrombocytopenia.

Hepato-biliary: Elevated liver enzymes.

Information for Pet Owners: M-Eloxyn 1.5 mg/mL oral suspension for dogs (Meloxicam) is a nonsteroidal anti-inflammatory drug (NSAID) and as with others in this class, adverse reactions may occur in treated dogs. The most common adverse reactions reported involve the gastrointestinal tract and usually occur within the first week of treatment. Typical symptoms include loss of appetite, vomiting, diarrhea, dark stools and depression. It is important in these situations to discontinue treatment and contact your veterinarian. In most cases, the adverse reactions are transient and disappear after termination of treatment but in rare instances may be serious or fatal especially if treatment is not discontinued. Dogs undergoing prolonged treatment with M-Eloxyn 1.5 mg/mL oral suspension for dogs should be monitored periodically. Consult your veterinarian. Shake well before use.

Safety: The safety profile of meloxicam has been evaluated in well controlled target animal safety studies in dogs. Dogs treated with placebo, 1X, 3X and 5X label dosages were closely monitored over a 180 day (26 week period). The study determined that there were no drug related adverse reactions on clinical observations, normal body weight gain, food consumption, physical and opthalmic examinations, clotting times, mucosal bleeding times or on a panel of clinical pathology parameters monitored throughout the study.


Store between 15-30°C.

Presentation: Plastic bottles of 15, 42, 100 or 200 mL supplied with a measuring syringe.

Zoetis® and M-Eloxyn are registered trademarks of Zoetis or its licensors.

Zoetis Canada Inc., Kirkland QC H9H 4M7

Date: 3 May 2013





15 mL



42 mL



100 mL



200 mL



CPN: 1198488.1

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