Gamma-Check-E (Canada)This page contains information on Gamma-Check-E for veterinary use.
The information provided typically includes the following:
- Gamma-Check-E Indications
- Warnings and cautions for Gamma-Check-E
- Direction and dosage information for Gamma-Check-E
Gamma-Check-EThis treatment applies to the following species:
WHEN TO TEST:
Foals ingesting good quality colostrum usually have > 800 mg IgG/dl by 4-8 hr old. Early testing allows oral supplementation with colostrum or plasma. After 16-24 hr of age immunoglobulin supplementation must occur parenterally.
A. WHOLE BLOOD
1. Add 1.5 ml to fill red line on GAMMA-CHECK tube (fresh or EDTA blood).
2. Swirl tube to ensure mixing & note time.
3. Tilt tube at 2 and 5 min - when blood no longer flows invert tube and gently tap - clot should remain firmly in place.
4. END POINT IS FORMATION OF A FIRM CLOT - IF THIS OCCURS IN LESS THAN 5 MIN THE IgG IS ABOVE 800 MG/DL
A jelly like clot that slips down the side is usually positive but should be retested using serum or a different type of test such as the Equine RID.
Sick foals (with elevated fibrinogen), dehydrated foals or hemolyzed samples may give false positive results. In these cases the Gamma-Check test should be run using serum or another test type.
1. Collect blood into a red top tube, allow to clot (30 min), then centrifuge to remove serum.
2. Repeat steps A 1-4 using serum.
On occasion a false negative can occur - we recommend retesting the foal with an other test, such as the Equine RID prior to a plasma transfusion.
The glutaraldehyde reagent is caustic, if skin or eye contact occurs wash with copious amount of water & consult physician.
DO NOT LEAVE TUBES LYING IN HOT SUN
Store at 4°C to prolong shelf life
1. Beetson, SA et al. The use of glutaraldehyde coagulation test for the detection of hypogammaglobulinemia in neonatal foals. Aust Vet J 62: 279-281, 1985.
2. Clabough DL et al. Comparison of four screening techniques for the diagnosis of equine neonatal hypogammaglobulinemia. JAVMA 194: 1717-1720, 1989.
3. Massey RE et al. Colostrum feeding of foals and colostrum banking. AAEP Proceedings 37: 1-15, 1991.
PLASSVACC®, 1535 Templeton Road, Templeton, CA 93465
Distributed by: Centaur V.A.
Presentation: 10 and 25 tests per kit.
1535 TEMPLETON ROAD, TEMPLETON, CA, 93465
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