Skip to main content

Eprecis (Canada)

This treatment applies to the following species:
Company: Ceva Animal Health

Eprinomectin Pour-On Solution

for Beef, Dairy Cattle, and Deer

VETERINARY USE ONLY

DIN 02527057

For the treatment of parasitic infections due to gastrointestinal roundworms (including inhibited Ostertagia ostertagi), lungworms, cattle grubs, and infestations due to sucking and biting lice, chorioptic and sarcoptic mange mites and horn flies in beef and dairy cattle; and for the treatment of parasitic infections due to gastrointestinal roundworms and lungworms in deer.

Product Description

Eprecis Pour-On for Beef and Dairy Cattle is a pale yellow to clear yellow solution, containing 5 mg of eprinomectin per mL. The active ingredient, eprinomectin, is an antiparasitic agent from the macrocyclic lactone family of compounds. Eprecis Pour-On is formulated for external use in beef cattle, dairy cattle and deer.

Note To Users

Consult your veterinarian for the diagnosis, treatment and control of parasitism in cattle and deer. For best results, Eprecis Pour-On should be used in a planned program to control both internal and external parasites.

Eprecis Indications

1. BEEF and DAIRY CATTLE:

Eprecis Pour-On is indicated for the treatment of parasitic infections and infestations due to the following gastrointestinal roundworms, lungworms, grubs, sucking and biting lice, mange mites and horn flies in beef and dairy cattle (including lactating dairy cattle):

 

Adults

L4

Inhibited L4

Gastrointestinal roundworms

Ostertagia ostertagi

O. lyrata

 

 

Haemonchus placei

 

Trichostrongylus axei

 

T. colubriformis

 

T. longispicularis

 

 

Cooperia oncophora

C. punctata

C. pectinata

C. surnabada (mcmasteri)

Nematodirus helvetianus

 

Oesophagostomum radiatum

 

Trichuris ovis

 

 

T. discolor

 

 

Bunostomum phlebotomum

 

Strongyloides papillosus

 

 

Lungworms

Dictyocaulus viviparus

 

Cattle Grubs (internal parasitic stages)

Hypoderma bovis

H. lineatum

Biting And Sucking Lice

Damalinia bovis

Linognathus vituli

Haematopinus eurysternus

Solenopotes capillatus

Mange Mites

Chorioptes bovis

Sarcoptes scabiei var bovis

Horn Flies

Haematobia irritans

2. DEER:

Eprecis Pour-On is indicated for the treatment of parasitic infections due to the following gastrointestinal roundworms and lungworms in deer:

 

Adults

L4

Gastrointestinal roundworms

Ostertagia-like spp.*

 

Trichostrongylus spp.

Oesophagostomum spp.

 

Mazamastrongylus spp.

 

Lungworms

Dictyocaulus viviparus

*(Includes O. mossi/dikmansi, O. lyrata, O. leptospicularis, Spiculopteratia spiculoptera and S. asymmetrica.)

Eprecis Dosage And Administration

Eprecis Pour-On is formulated to deliver the recommended dose level of 500 μg of eprinomectin per kg of body weight in target animals, at the rate of 1 mL per 10 kg body weight. The formulation should be applied topically along the backline, in a narrow strip extending from the withers to the tail head.

Backpack (1 L, 2.5 L, and 5 L):

To be used with an appropriate dosing system such as a dosing gun and coupling vented cap. Unscrew the cap. Remove the protective seal from the bottle. Screw a coupling vented cap on the bottle and make sure it is tightened. Connect the other side to a dosing gun. Follow the gun manufacturer’s instructions for adjusting the dose and proper use and maintenance of the dosing gun and vented cap. After use, the coupling vented cap should be removed and replaced by the non-vented cap.

CAUTIONS

1. For topical application only: do not administer orally or by injection.

2. Do not apply to areas of the backline covered with mud or manure.

3. To prevent potential adverse reactions when treating infections with cattle grubs, consult your veterinarian on the correct timing of treatment.

4. No data are available on the effect of this product on the breeding performance of male and female deer.

WARNINGS

● No withdrawal period is required for cattle and deer when treated according to the label.

● No milk withholding time is required for cattle when used according to the label.

● Avoid contact with skin and eyes. If accidental skin contact occurs, wash the affected area immediately with soap and water. If accidental eye exposure occurs, flush eyes immediately with water.

● Keep out of reach of children.

Mode Of Action

Eprinomectin is a member of the macrocyclic lactone class of endectocides which have a unique mode of action. Compounds of the class bind selectively and with high affinity to glutamate-gated chloride ion channels which occur in invertebrate nerve and muscle cells. This leads to an increase in the permeability of the cell membrane to chloride ions with hyperpolarization of the nerve or muscle cell, resulting in paralysis and death of the parasite. Compounds of this class may also interact with other ligand-gated chloride channels, such as those gated by the neurotransmitter gamma-aminobutyric acid (GABA).

The margin of safety for compounds of this class is attributable to the fact that mammals do not have glutamate-gated chloride channels; the macrocyclic lactones have a low affinity for other mammalian ligand-gated chloride channels and they do not readily cross the blood-brain barrier.

Safety

Studies have demonstrated a wide safety margin in target animals. Three times the recommended dose level had no adverse effect on breeding performance of cows or bulls. Treatment at five times the recommended therapeutic dose had no adverse effect on deer.

Efficacy

Eprecis Pour-On administered at the recommended dosage of 500 μg of eprinomectin per kg of body weight, effectively controls parasitic infestations with Haematobia irritans (horn flies) for up to 7 days after treatment. For optimal control of horn flies, Eprecis Pour-On should be used as part of an integrated control program. Consult your veterinarian for the most effective timing of applications.

Persistent Activity

Eprecis Pour-On administered at the recommended dosage of 500 μg of eprinomectin per kg of body weight, effectively controls parasitic infections with Ostertagia ostertagi, Nematodirus helvetianus, and Dictyocaulus viviparus for 28 days after treatment, Cooperia oncophora, C. punctata and C. surnabada (mcmasteri) for 21 days after treatment and Haemonchus placei, Trichostrongylus axei, T. colubriformis and Oesophagostomum radiatum for 14 days after treatment.

Rainfall anytime before or after treatment will not affect the efficacy of the product.

Storage

Store between 15°C to 30°C.

Use within 6 months of first opening the container.

Environmental Safety

Studies indicate that when eprinomectin comes in contact with the soil, it readily and tightly binds to the soil and becomes inactive. Drug containers and any residual contents should be disposed of safely (e.g. by burying or incinerating) as free eprinomectin may adversely affect fish and certain aquatic organisms.

PACKAGING

Eprecis Pour-On for beef cattle, dairy cattle, and deer, is available in three ready to use sizes: 1 L, 2.5 L and 5 L.

1 L - is supplied in a multiple-dose pack designed for use with appropriate dosing equipment.

Each pack contains enough solution to treat 40 x 250 kg of body weight (one mL per 10 kg).

2.5 L - is supplied in a multiple-dose pack designed for use with appropriate dosing equipment.

Each pack contains enough solution to treat 100 x 250 kg of body weight (one mL per 10 kg).

5 L -is supplied in a multiple-dose pack designed for use with appropriate dosing equipment.

Each pack contains enough solution to treat 200 x 250 kg of body weight (one mL per 10 kg).

Ceva Animal Health Inc., 150 Research Lane, Suite 225, Guelph ON N1G 4T2

1-800-510-8864

C7135-3120105

CPN: 1221168.0

CEVA ANIMAL HEALTH INC.
150 RESEARCH LANE, SUITE 225, GUELPH, ON, N1G 4T2
Telephone:   519-650-9570
Toll-Free:   800-510-8864
Fax:   519-650-9576
Website:   www.ceva-canada.ca
Email:   service.canada@ceva.com
THIS SERVICE AND DATA ARE PROVIDED "AS IS". Animalytix assumes no liability, and each user assumes full risk, responsibility, and liability, related to its use of the Animalytix service and data. See the Terms of Use for further details.

Animalytix

Copyright © 2025 Animalytix LLC. Updated: 2025-03-02