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Bovilis Guardian (Canada)

This page contains information on Bovilis Guardian for veterinary use.
The information provided typically includes the following:
  • Bovilis Guardian Indications
  • Warnings and cautions for Bovilis Guardian
  • Direction and dosage information for Bovilis Guardian

Bovilis Guardian

This treatment applies to the following species:
Company: Merck Animal Health

Bovine Rotavirus-Coronavirus Vaccine, Killed Virus, Clostridium Perfringens Type C & D-Escherichia Coli Bacterin-Toxoid

Cattle Vaccine

Bovilis® Guardian™ vaccine is a multiple antigen product which includes a cell-free extract of K99 pilus type of Escherichia coli, a unique combination of two inactivated coronaviruses, two G-types of inactivated rotaviruses and a bacterin-toxoid from Clostridium perfringens Types C and D. It is recommended for use in healthy pregnant heifers and cows as an aid in the prevention of neonatal calf diarrhea caused by bovine Group A Serotype G6 rotaviruses, enterotoxigenic E. coli pilus type K99, and enterotoxemia caused by C. perfringens Types C & D, and as an aid in the control of neonatal calf diarrhea caused by bovine coronavirus.

DOSAGE: Using aseptic technique, inject healthy pregnant cattle with 2 mL subcutaneously 3 months prior to calving. Repeat in 3 - 6 weeks following initial vaccination. For subsequent calvings, revaccinate with a single 2 mL dose 5 - 7 weeks before calving. For E. Coli, protection was shown when the first dose was given as early as six months prior to calving.

Bovilis Guardian Caution

Store at 2° to 7°C (35° to 45°F). Do not freeze. Shake well before use. Use entire contents when first opened. Do not vaccinate within 60 days prior to slaughter. Transient local reaction may occur at the injection site. If allergic response occurs, administer epinephrine.

PRESERVATIVES: Gentamicin and thimerosal. FOR ANIMAL USE ONLY.

Intervet Inc. d/b/a Merck Animal Health, Omaha, NE 68103, USA

VLN 165A/PCN 4575.20

1 800 521-5767 (USA)

1 866 683-7838 (CAN)

For Patent info.:





10 Doses

20 mL




50 Doses

100 mL




CPN: 1208297.0

Intervet Canada Corp.

Order Desk:   514-428-7013
Toll-Free:   866-683-7838
Fax:   Toll-free 888-498-4444; local 514-428-7014
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