AviPro Thymovac (Canada)

Directions For Use

CHICKEN ANEMIA VIRUS VACCINE, MODIFIED LIVE VIRUS

For use in animals only

This product has been shown to be effective for active immunization of chickens against viremia, excretion and transmission of the chicken anemia virus to eggs. Onset of immunity occurs within 4 weeks of vaccination and the duration of immunity is 43 weeks after vaccination.

This product has been shown to be effective for passive protection conferred to the progeny against clinical signs and lesions of the chicken infectious anemia. Protection of progeny is established for up to 51 weeks after vaccination of the breeder, and chicks are protected from one day of age (as demonstrated by challenge).

AviPro™ Thymovac is a lyophilisate for administration via drinking water. It is recommended for use in chickens (breeders) from 8 weeks of age to a maximum of 6 weeks before onset of lay.

Administration in drinking water:

For administration via drinking water after reconstitution. Carefully follow the instructions below for correct administration so that all birds receive the correct dose.

1. All equipment used for vaccination (tubes, drinkers, etc.) should be thoroughly cleaned and free from detergent or disinfectant residues. The drinking water system should be emptied before vaccination.

2. Estimate the amount of water according to the number of birds to be vaccinated. Prepare only the amount of vaccine that can be consumed within 2 hours. In case of doubt, the uptake of water should be estimated before vaccination.

3. Ensure that water is cold, clean, non-chlorinated and free from detergents, disinfectants and metal ions. Low-fat skimmed milk powder (i.e., <1% fat) may be added to the water (2 - 4 grams per litre) or skimmed milk (20 - 40 mL per litre of water) to improve the water quality and to increase the stability of the virus. This, however, has to be done at least 10 minutes prior to reconstitution of the vaccine.

4. For easy handling the vaccine should be resuspended in a small container (about 1 L). Rinse the vial carefully and empty it completely. The vaccine suspension is then diluted in a larger vessel (5 - 10 L) and mixed well again. Once resuspended, administer the ready-to-use vaccine immediately.

The complete content of the vaccine vial should be used for one flock or drinking water system only. Splitting of the diluted vaccine may lead to dosage errors.

5. Ideally the vaccine should be administered in the volume of water consumed by the birds in up to 2 hours. Apply diluted vaccine to cold and fresh water at a rate of 1000 doses of vaccine to 20 - 40 L of water for 1000 chickens.

Since drinking behaviour of chickens can vary, it might be necessary to withdraw the drinking water for 2 - 3 hours before vaccination to ensure that all birds will drink during the vaccination phase.

Warnings

Vaccinate only healthy birds.

Do not use in birds in lay and no later than six weeks before the onset of lay.

Avoid contact with day-old chicks.

Vaccinated chickens may excrete the virus in feces for 14 days up to 4 weeks. Avoid contact of vaccinated and unvaccinated animals. Care should be taken to avoid contamination (i.e., by sprinkling or spilling) by wearing personal protective equipment like gloves, protecting eyes, and washing and disinfecting hands after handling the vaccine.

Do not mix with other products, except as specified on the labelling.

Withdrawal period: 21 days

Keep out of reach of children.

Storage Conditions:

Store in refrigerator at 2°C to 8°C. Protect from light and frost. Do not freeze.

Shelf-life after reconstitution according to directions: 2 hours. Protect reconstituted vaccine from direct sunlight and from temperatures above 25°C.

Presentation:

AviPro™ Thymovac is available in boxes containing one or ten type 1 glass bottles with 1000 doses per bottle, and in boxes containing one or ten type 1 glass bottles with 2500 doses per bottle. Not all pack sizes may be marketed.

Manufactured in Germany by:

Lohmann Animal Health GmbH, Heinz-Lohmann-Strasse 4, 27472 Cuxhaven, Germany

AviPro, Elanco and the diagonal bar logo are trademarks of Elanco or its affiliates.

© 2024 Elanco or its affiliates.

PA950011X 240926 49

CPN: 1231252.0