Zovirax Ointment Side Effects

Generic name: acyclovir topical

Medically reviewed by Drugs.com. Last updated on Oct 24, 2023.

Note: This document provides detailed information about Zovirax Ointment Side Effects associated with acyclovir topical. Some dosage forms listed on this page may not apply specifically to the brand name Zovirax Ointment.

Applies to acyclovir topical: topical cream, topical ointment.

Precautions

Women with genital herpes may be more likely to get cancer of the cervix (opening to the womb). Therefore, it is very important that Pap tests be taken at least once a year to check for cancer. Cervical cancer can be cured if found and treated early.

If your symptoms do not improve within 1 week, or if they become worse, check with your doctor.

Consider the possibility of viral resistance to acyclovir if little or no improvement in symptoms during therapy.

The areas affected by herpes should be kept as clean and dry as possible. Also, wear loose-fitting clothing to avoid irritating the sores (blisters).

Herpes infection of the genitals can be caught from or spread to your partner during any sexual activity. Although you may get herpes even though your sexual partner has no symptoms, the infection is more likely to be spread if sores are present. This is true until the sores are completely healed and the scabs have fallen off. The use of a condom (prophylactic) may help prevent the spread of herpes. However, spermicidal (sperm-killing) jelly or a diaphragm will not help prevent the spread of herpes. Therefore, it is best to avoid any sexual activity if either you or your partner has any symptoms of herpes. It is also important to remember that acyclovir will not keep you from spreading herpes to others.

Common side effects of Zovirax Ointment

Some side effects of acyclovir topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Serious side effects of Zovirax Ointment

Along with its needed effects, acyclovir topical (the active ingredient contained in Zovirax Ointment) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

For healthcare professionals

Applies to acyclovir topical: topical cream, topical ointment.

General adverse events

The more commonly reported adverse effects have included local application site reactions including transient stinging and burning.^[Ref]

Dermatologic

• Very common (10% or more): Mild pain including transient burning and stinging (30%) at application site
• Common (1% to 10%): Local pruritus
• Rare (less than 0.1%): Erythema
• Frequency not reported: Dry lips, desquamation, dryness of skin, cracked lips, burning skin, flakiness of skin
• Postmarketing reports: Contact dermatitis, eczema^[Ref]

The incidence of events between the drug and placebo group appears to be similar. Where sensitivity tests have been conducted, the reactive substance has often been the component of the cream rather than the active drug.^[Ref]

Hypersensitivity

• Postmarketing reports: Angioedema, anaphylaxis

Cardiovascular

• Postmarketing reports: Edema

See also:

Further information

Zovirax Ointment side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer