Skip to Content

Xhance Side Effects

Generic Name: fluticasone nasal

Note: This document contains side effect information about fluticasone nasal. Some of the dosage forms listed on this page may not apply to the brand name Xhance.

For the Consumer

Applies to fluticasone nasal: nasal spray

Along with its needed effects, fluticasone nasal (the active ingredient contained in Xhance) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking fluticasone nasal:

More common

  • Bloody nose
  • cough
  • fever
  • headache
  • muscle aches
  • pain or tenderness around the eyes and cheekbones
  • sore throat
  • stuffy or runny nose
  • tightness of the chest
  • troubled breathing
  • unusual tiredness or weakness

Less common

  • Blurred vision
  • change in vision
  • loss of vision

Incidence not known

  • Difficulty with swallowing
  • dizziness
  • fast heartbeat
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • redness of the skin
  • skin rash, itching, hives or welts

Some side effects of fluticasone nasal may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  • Back pain
  • dizziness
  • pain in the mouth and nose
  • stomach discomfort
  • toothache
  • weight increased

For Healthcare Professionals

Applies to fluticasone nasal: nasal spray

Endocrine

Frequency not reported: Hypothalamic-pituitary-adrenal (HPA) axis effects (including growth reduction)[Ref]

Nervous system

Common (1% to 10%): Headache, unpleasant taste, unpleasant smell[Ref]

Gastrointestinal

Common (1% to 10%): Toothache, nausea, diarrhea, abdominal distension, vomiting, gastrointestinal gaseous symptoms
Frequency not reported: Gum signs and symptoms[Ref]

Hypersensitivity

Very rare (less than 0.01%): Hypersensitivity reactions (including anaphylaxis, angioedema, rash, urticaria, bronchospasm)[Ref]

Ocular

Common (1% to 10%): Conjunctivitis
Very rare (less than 0.01%): Cataracts, glaucoma, raised intraocular pressure
Frequency not reported: Transient ocular changes[Ref]

Immunologic

Frequency not reported: Candida albicans infection, immunosuppression[Ref]

Respiratory

Very common (10% or more): Nasopharyngitis (26%), epistaxis (20%)
Common (1% to 10%): Pharyngolaryngeal pain, nasal ulceration, cough, pharyngitis, bronchitis, nasal dryness, throat irritation, throat dryness, blood in nasal mucosa, nasal irritation
Uncommon (0.1% to 1%): Rhinalgia, nasal discomfort (including nasal burning, nasal soreness)
Postmarketing reports: Nasal septal perforation[Ref]

General

The most commonly reported side effects were nasopharyngitis, epistaxis, and pyrexia.[Ref]

Musculoskeletal

Common (1% to 10%): Back pain[Ref]

Other

Very common (10% or more): Pyrexia
Frequency not reported: Impaired wound healing[Ref]

References

1. Cerner Multum, Inc. "Australian Product Information." O 0

2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

3. "Product Information. Flonase (fluticasone)." Glaxo Wellcome, Research Triangle Park, NC.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Hide